Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68384
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccnd1
Name: cyclin D1
Acc ID: CHEBI:82335
Term: Indeno[1,2,3-cd]pyrene
Definition: A pyrene that has formula C22H12.
Chemical ID: MESH:C041508
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccnd1increases expressionISOCCND1 (Homo sapiens)6480464CTDindeno(1,2,3-cd)pyrene results in increased expression of CCND1 mRNAPMID:35687267
Ccnd1multiple interactionsISOCCND1 (Homo sapiens)6480464CTD1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CCND1 protein]; 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CCND1 protein]; AHR protein promotes the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CCND1 protein]; epacadostat inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CCND1 protein]; U 0126 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CCND1 protein]PMID:35687267
Go Back to source page   Continue to Ontology report