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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68335
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Por
Name: cytochrome p450 oxidoreductase
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Porincreases expressionEXP 6480464CTDCadmium Chloride results in increased expression of POR mRNAPMID:33453195
Pordecreases expressionISOPor (Mus musculus)6480464CTDCadmium Chloride results in decreased expression of POR mRNAPMID:11958953
Porincreases activityISOPOR (Homo sapiens)6480464CTDCadmium Chloride results in increased activity of POR proteinPMID:20934533
Porincreases expressionISOPOR (Homo sapiens)6480464CTDCadmium Chloride results in increased expression of POR mRNA; Cadmium Chloride results in increased expression of POR proteinPMID:24527689 PMID:38568856
Pormultiple interactionsISOPOR (Homo sapiens)6480464CTDdiphenyleneiodonium inhibits the reaction [Cadmium Chloride results in increased activity of POR protein]PMID:20934533
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