GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il12b | decreases expression | ISO | IL12B (Homo sapiens) | 6480464 | CTD | apilimod results in decreased expression of IL12B mRNA | PMID:21348542 | Il12b | multiple interactions | ISO | IL12B (Homo sapiens) | 6480464 | CTD | apilimod inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased secretion of [IL12A protein binds to IL12B protein]]; apilimod inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased secretion of [IL23A protein binds to IL12B protein]]; apilimod inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased secretion of IL12B protein] | PMID:17053051 PMID:23890009 | Il12b | multiple interactions | ISO | Il12b (Mus musculus) | 6480464 | CTD | apilimod inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased secretion of IL12B protein] | PMID:23890009 | |
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