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GENE - TERM ANNOTATION REPORT

RGD ID: 628658
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bmf
Name: Bcl2 modifying factor
Acc ID: GO:0090200
Term: positive regulation of release of cytochrome c from mitochondria
Definition: Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
Definition Source(s): GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:tb
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bmfinvolved_inISOBmf (Mus musculus)1624291RGDUniProtKB:P70444 MGI:5009775 PMID:21041309

MGI:5009775 PMID:21041309
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