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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62221
Species: Mus musculus
RGD Object: Gene
Symbol: Hif1a
Name: hypoxia inducible factor 1, alpha subunit
Acc ID: CHEBI:17833
Term: gentamycin
Definition: Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp.
Chemical ID: MESH:D005839
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hif1adecreases expressionISOHif1a (Rattus norvegicus)6480464CTDGentamicins results in decreased expression of HIF1A mRNAPMID:22061828
Hif1aincreases expressionISOHif1a (Rattus norvegicus)6480464CTDGentamicins results in increased expression of HIF1A mRNAPMID:18656965 PMID:22061828 PMID:23145036 PMID:33387578
Hif1amultiple interactionsISOHif1a (Rattus norvegicus)6480464CTD[Gentamicins co-treated with cobaltous chloride] results in increased expression of HIF1A proteinPMID:23145036
Hif1amultiple interactionsISOHIF1A (Homo sapiens)6480464CTD[Gentamicins co-treated with cobaltous chloride] results in increased expression of HIF1A proteinPMID:23145036
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