Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621652
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Klf10
Name: KLF transcription factor 10
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Klf10increases expressionEXP 6480464CTDEstradiol results in increased expression of KLF10 mRNAPMID:32145629 PMID:35192832
Klf10affects expressionISOKLF10 (Homo sapiens)6480464CTDEstradiol affects the expression of KLF10 mRNAPMID:14699072
Klf10affects expressionISOKlf10 (Mus musculus)6480464CTDEstradiol affects the expression of KLF10 mRNAPMID:15598610
Klf10decreases expressionISOKLF10 (Homo sapiens)6480464CTDEstradiol results in decreased expression of KLF10 mRNAPMID:11179685
Klf10increases expressionISOKLF10 (Homo sapiens)6480464CTDEstradiol results in increased expression of KLF10 mRNAPMID:31614463
Klf10multiple interactionsISOKLF10 (Homo sapiens)6480464CTD3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of KLF10 mRNA]; [Estradiol co-treated with TGFB1 protein] results in increased expression of KLF10 mRNA; Tetrachlorodibenzodioxin promotes the reaction [Estradiol results in decreased expression of KLF10 mRNA]PMID:11179685 PMID:30165855
Go Back to source page   Continue to Ontology report