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Gene: KLF10 (Kruppel like factor 10) Homo sapiens
Symbol: KLF10
Name: Kruppel like factor 10
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: early growth response-alpha; EGR-alpha; EGRA; Krueppel-like factor 10; Kruppel-like factor 10; TGFB inducible early growth response; TGFB-inducible early growth response protein 1; TIEG; TIEG-1; TIEG1; transforming growth factor-beta-inducible early growth response protein 1; zinc finger transcription factor TIEG
Mus musculus (house mouse) : Klf10 (Kruppel-like factor 10)  MGI  Alliance
Rattus norvegicus (Norway rat) : Klf10 (Kruppel-like factor 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klf10 (Kruppel like factor 10)
Pan paniscus (bonobo/pygmy chimpanzee) : KLF10 (Kruppel like factor 10)
Canis lupus familiaris (dog) : KLF10 (Kruppel like factor 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klf10 (Kruppel like factor 10)
Sus scrofa (pig) : KLF10 (Kruppel like factor 10)
Chlorocebus sabaeus (African green monkey) : KLF10 (Kruppel like factor 10)
Heterocephalus glaber (naked mole-rat) : Klf10 (Kruppel like factor 10)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl8102,648,784 - 102,655,725 (-)Ensembl
GRCh388102,648,777 - 102,655,725 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378103,661,005 - 103,668,130 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368103,730,188 - 103,737,128 (-)NCBINCBI36hg18NCBI36
Build 348103,730,196 - 103,737,128NCBI
Celera899,848,329 - 99,855,302 (-)NCBI
Cytogenetic Map8q22.3NCBI
HuRef898,862,246 - 98,869,150 (-)NCBIHuRef
CHM1_18103,701,211 - 103,708,326 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KLF10
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1348365
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.