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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621646
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vim
Name: vimentin
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vimdecreases expressionISOVIM (Homo sapiens)6480464CTDAcetylcysteine results in decreased expression of VIM proteinPMID:34687772
Vimmultiple interactionsISOVIM (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of VIM protein]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of VIM protein]; Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in decreased expression of VIM protein]PMID:28284859 PMID:32687844 PMID:33131013 PMID:34687772
Vimmultiple interactionsISOVim (Mus musculus)6480464CTDAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of VIM protein]; Acetylcysteine inhibits the reaction [SHC1 protein results in increased expression of VIM protein]PMID:32659284
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