GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk8 | multiple interactions | EXP | | 6480464 | CTD | [Sodium Selenite co-treated with coenzyme Q10] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein] | PMID:37967787 | Mapk8 | decreases activity | ISO | MAPK8 (Homo sapiens) | 6480464 | CTD | Sodium Selenite results in decreased activity of MAPK8 protein | PMID:10644709 | Mapk8 | decreases expression | ISO | MAPK8 (Homo sapiens) | 6480464 | CTD | Sodium Selenite results in decreased expression of MAPK8 mRNA | PMID:18175754 | Mapk8 | increases phosphorylation | ISO | MAPK8 (Homo sapiens) | 6480464 | CTD | Sodium Selenite results in increased phosphorylation of MAPK8 protein | PMID:34520753 | Mapk8 | multiple interactions | ISO | MAPK8 (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [Sodium Selenite results in increased phosphorylation of MAPK8 protein]; Dithiothreitol inhibits the reaction [Sodium Selenite results in decreased activity of MAPK8 protein]; MAPK8 protein affects the reaction [Sodium Selenite results in decreased activity of JUN protein]; Mercaptoethanol inhibits the reaction [Sodium Selenite results in decreased activity of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK8 protein | PMID:10644709 PMID:18728404 PMID:34520753 | Mapk8 | multiple interactions | ISO | Mapk8 (Mus musculus) | 6480464 | CTD | Sodium Selenite inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein] | PMID:18481333 PMID:26522834 | | ||||||||||||||||||||||
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