GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk8 | decreases expression | ISO | Mapk8 (Mus musculus) | 6480464 | CTD | Silicon Dioxide results in decreased expression of MAPK8 mRNA | PMID:19073995 | Mapk8 | increases phosphorylation | ISO | MAPK8 (Homo sapiens) | 6480464 | CTD | Silicon Dioxide analog results in increased phosphorylation of MAPK8 protein; Silicon Dioxide results in increased phosphorylation of MAPK8 protein | PMID:24844442 PMID:26163174 PMID:31082419 PMID:34653535 PMID:35689653 | Mapk8 | increases phosphorylation | ISO | Mapk8 (Mus musculus) | 6480464 | CTD | Silicon Dioxide results in increased phosphorylation of MAPK8 protein | PMID:27616297 | Mapk8 | multiple interactions | ISO | MAPK8 (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Silicon Dioxide results in increased phosphorylation of MAPK8 protein] | PMID:35689653 | | ||||||||||||||||||||||
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