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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620927
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc27a1
Name: solute carrier family 27 member 1
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc27a1decreases methylationEXP 6480464CTDCadmium Chloride results in decreased methylation of SLC27A1 promoterPMID:22457795
Slc27a1decreases expressionISOSlc27a1 (Mus musculus)6480464CTDCadmium Chloride results in decreased expression of SLC27A1 mRNA; Cadmium Chloride results in decreased expression of SLC27A1 proteinPMID:31152847
Slc27a1multiple interactionsISOSlc27a1 (Mus musculus)6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SLC27A1 mRNAPMID:29373603
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