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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620857
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pla2g2a
Name: phospholipase A2 group IIA
Acc ID: CHEBI:31429
Term: colforsin daropate hydrochloride
Definition: The hydrochloride salt of colforsin daropate. It is a drug used for the treatment of acute heart failure. It directly stimulates adenylate cyclase and produces positive inotropic and vasodilator effects accompanied by the increase in cellular cAMP.
Chemical ID: MESH:D005576
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pla2g2amultiple interactionsISOPLA2G2A (Homo sapiens)6480464CTDColforsin inhibits the reaction [IFNG protein promotes the reaction [decitabine results in increased expression of PLA2G2A protein]]PMID:18953428
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