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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hes1
Name: hes family bHLH transcription factor 1
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hes1decreases expressionISOHES1 (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of HES1 mRNAPMID:20458559 PMID:23497375 PMID:24685274
Hes1multiple interactionsISOHES1 (Homo sapiens)6480464CTDArsenic Trioxide inhibits the reaction [PROM1 protein results in increased expression of HES1 mRNA]PMID:23832679
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