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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620763
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccn1
Name: cellular communication network factor 1
Acc ID: CHEBI:5001
Term: fenofibrate
Definition: A chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring.
Chemical ID: MESH:D011345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccn1decreases expressionISOCCN1 (Homo sapiens)6480464CTDFenofibrate results in decreased expression of CCN1 mRNAPMID:25572481
Ccn1increases expressionISOCcn1 (Mus musculus)6480464CTDFenofibrate results in increased expression of CCN1 proteinPMID:39442682
Ccn1multiple interactionsISOCcn1 (Mus musculus)6480464CTD[Galactose co-treated with Fenofibrate] results in increased expression of CCN1 proteinPMID:39442682
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