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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620600
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nox4
Name: NADPH oxidase 4
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nox4decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of NOX4 mRNAPMID:25181051
Nox4increases expressionISONOX4 (Homo sapiens)6480464CTDbisphenol A results in increased expression of NOX4 mRNAPMID:36633214
Nox4increases expressionISONox4 (Mus musculus)6480464CTDbisphenol A results in increased expression of NOX4 mRNAPMID:36633214
Nox4multiple interactionsISONOX4 (Homo sapiens)6480464CTDMelatonin inhibits the reaction [bisphenol A results in increased expression of NOX4 mRNA]PMID:36633214
Nox4multiple interactionsISONox4 (Mus musculus)6480464CTDMelatonin inhibits the reaction [bisphenol A results in increased expression of NOX4 mRNA]PMID:36633214
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