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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620600
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nox4
Name: NADPH oxidase 4
Acc ID: CHEBI:3139
Term: bleomycin A2
Definition: A bleomycin that has formula C55H84N17O21S3.
Chemical ID: MESH:D001761
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nox4increases expressionISONox4 (Mus musculus)6480464CTDBleomycin results in increased expression of NOX4 mRNAPMID:35187969 PMID:37307957
Nox4multiple interactionsISONox4 (Mus musculus)6480464CTDgeranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of NOX4 mRNA]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of NOX4 mRNA]PMID:35187969 PMID:37307957
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