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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62043
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Xdh
Name: xanthine dehydrogenase
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Xdhincreases activityEXP 6480464CTDCarbon Tetrachloride results in increased activity of XDH proteinPMID:30825423
Xdhmultiple interactionsEXP 6480464CTD12-tungstophosphoric acid inhibits the reaction [Carbon Tetrachloride results in increased activity of XDH protein]; Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased activity of XDH protein]; Carbon Tetrachloride results in increased expression of and results in increased activity of XDH protein; sodium tungstate(VI) inhibits the reaction [Carbon Tetrachloride results in increased activity of XDH protein]PMID:17727797 PMID:30825423
Xdhaffects expressionISOXdh (Mus musculus)6480464CTDCarbon Tetrachloride affects the expression of XDH mRNAPMID:17484886
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