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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620416
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dnm1l
Name: dynamin 1-like
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dnm1lmultiple interactionsEXP 6480464CTD[Cocaine co-treated with Cocaine deficiency] promotes the reaction [RUNX2 protein binds to DNM1L promoter]PMID:30158054
Dnm1lincreases phosphorylationISODnm1l (Mus musculus)6480464CTDCocaine results in increased phosphorylation of DNM1L proteinPMID:31494168
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