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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620103
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bad
Name: BCL2-associated agonist of cell death
Acc ID: CHEBI:79
Term: (-)-Arctigenin
Definition: A lignan that has formula C21H24O6.
Chemical ID: MESH:C071942
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baddecreases phosphorylationISOBAD (Homo sapiens)6480464CTDarctigenin results in decreased phosphorylation of BAD proteinPMID:25380086
Badincreases expressionISOBAD (Homo sapiens)6480464CTDarctigenin results in increased expression of BAD mRNAPMID:25922263
Badmultiple interactionsISOBAD (Homo sapiens)6480464CTDQuercetin promotes the reaction [arctigenin results in decreased phosphorylation of BAD protein]PMID:25380086
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