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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619951
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb1a
Name: ATP binding cassette subfamily B member 1A
Acc ID: CHEBI:32168
Term: sulpiride
Definition: A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Chemical ID: MESH:D013469
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb1aincreases transportISOABCB1 (Homo sapiens)6480464CTDABCB1 protein results in increased transport of SulpiridePMID:28597291
Abcb1amultiple interactionsISOABCB1 (Homo sapiens)6480464CTDVerapamil inhibits the reaction [ABCB1 protein results in increased transport of Sulpiride]PMID:28597291
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