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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61959
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Txnrd1
Name: thioredoxin reductase 1
Acc ID: CHEBI:50866
Term: 3H-1,2-dithiole-3-thione
Definition: A 1,2-dithiole that has formula C3H2S3.
Chemical ID: MESH:C049325
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Txnrd1multiple interactionsISOTxnrd1 (Mus musculus)6480464CTD[1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of TXNRD1 mRNAPMID:22495766
Txnrd1multiple interactionsISOTXNRD1 (Homo sapiens)6480464CTD1,2-dithiol-3-thione results in increased expression of and results in increased activity of TXNRD1 proteinPMID:25179160
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