3H-1,2-dithiole-3-thione - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	3H-1,2-dithiole-3-thione	go back to main search page
Accession:	CHEBI:50866	browse the term
Definition:	A 1,2-dithiole that has formula C3H2S3.
Synonyms:	related_synonym:	1,2-dithiol-3-thione; 1,2-dithiole-3-thione; Formula=C3H2S3; InChI=1S/C3H2S3/c4-3-1-2-5-6-3/h1-2H; InChIKey=LZENMJMJWQSSNJ-UHFFFAOYSA-N; SMILES=S=c1ccss1
	xref:	Beilstein:106380; CAS:534-25-8; LINCS:LSM-4759
	xref_mesh:	MESH:C049325

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Genes (853)

3H-1,2-dithiole-3-thione

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

increases expression

1,2-dithiol-3-thione results in increased expression of A2M mRNA

NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:154,897,877...154,947,786

G

ATP binding cassette subfamily B member 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of ABCB4 mRNA

NCBI chr 4:26,106,895...26,164,440
Ensembl chr 4:25,151,953...25,209,202

G

ATP binding cassette subfamily D member 3

increases expression

1,2-dithiol-3-thione results in increased expression of ABCD3 mRNA

NCBI chr 2:212,536,791...212,590,379
Ensembl chr 2:209,852,087...209,906,020

G

abhydrolase domain containing 13

decreases expression

1,2-dithiol-3-thione results in decreased expression of ABHD13 mRNA

NCBI chr16:86,203,851...86,218,843
Ensembl chr16:79,501,727...79,516,748

G

acetyl-CoA acyltransferase 1A

increases expression

1,2-dithiol-3-thione results in increased expression of ACAA1 mRNA

NCBI chr 8:127,956,126...127,966,348
Ensembl chr 8:119,079,775...119,088,624

G

acyl-CoA dehydrogenase, short/branched chain

decreases expression

1,2-dithiol-3-thione results in decreased expression of ACADSB mRNA

NCBI chr 1:195,619,088...195,660,564
Ensembl chr 1:186,188,987...186,230,379

G

acetyl-CoA acetyltransferase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of ACAT2 mRNA

NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:47,695,788...47,752,821

G

ATP citrate lyase

increases expression

1,2-dithiol-3-thione results in increased expression of ACLY mRNA

NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320

G

acyl-CoA thioesterase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of ACOT2 mRNA

NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:103,611,544...103,619,245

G

acyl-CoA synthetase long-chain family member 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of ACSL4 mRNA

NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427

G

acyl-CoA synthetase long-chain family member 5

decreases expression

1,2-dithiol-3-thione results in decreased expression of ACSL5 mRNA

NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:254,292,521...254,336,607

G

adhesion G protein-coupled receptor L2

decreases expression

1,2-dithiol-3-thione results in decreased expression of ADGRL2 mRNA

NCBI chr 2:237,696,055...238,327,141
Ensembl chr 2:237,696,056...238,327,141

G

adenosine A2B receptor

increases expression

1,2-dithiol-3-thione results in increased expression of ADORA2B mRNA

NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772

G

ADP-ribosylarginine hydrolase

increases expression

1,2-dithiol-3-thione results in increased expression of ADPRH mRNA

NCBI chr11:62,299,831...62,306,170
Ensembl chr11:62,299,793...62,306,931

G

adrenoceptor alpha 1B

decreases expression

1,2-dithiol-3-thione results in decreased expression of ADRA1B mRNA

NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919

G

adrenoceptor alpha 2C

increases expression

1,2-dithiol-3-thione results in increased expression of ADRA2C mRNA

NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846

G

aftiphilin

decreases expression

1,2-dithiol-3-thione results in decreased expression of AFTPH mRNA

NCBI chr14:94,871,429...94,925,625
Ensembl chr14:94,871,429...94,925,376

G

agrin

decreases expression

1,2-dithiol-3-thione results in decreased expression of AGRN mRNA

NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003

G

ATP/GTP binding carboxypeptidase 1

increases expression

1,2-dithiol-3-thione results in increased expression of AGTPBP1 mRNA

NCBI chr17:5,092,108...5,244,414
Ensembl chr17:5,120,609...5,238,869

G

angiotensin II receptor, type 1a

decreases expression

1,2-dithiol-3-thione results in decreased expression of AGTR1A mRNA

NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,174,429...34,226,946

G

alanine--glyoxylate aminotransferase

increases expression

1,2-dithiol-3-thione results in increased expression of AGXT mRNA

NCBI chr 9:101,122,793...101,132,746
Ensembl chr 9:93,675,384...93,685,336

G

allograft inflammatory factor 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of AIF1 mRNA

NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,646,777...3,652,668

G

adenylate kinase 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of AK3 mRNA

NCBI chr 1:236,151,012...236,178,689
Ensembl chr 1:226,739,318...226,764,625

G

A-kinase anchoring protein 12

decreases expression

1,2-dithiol-3-thione results in decreased expression of AKAP12 mRNA

NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886

G

A-kinase anchoring protein 8

decreases expression

1,2-dithiol-3-thione results in decreased expression of AKAP8 mRNA

NCBI chr 7:11,316,224...11,332,523
Ensembl chr 7:11,316,228...11,332,399

G

aldo-keto reductase family 1 member A1

increases expression

1,2-dithiol-3-thione results in increased expression of AKR1A1 mRNA

NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674

G

aldo-keto reductase family 1, member D1

increases expression

1,2-dithiol-3-thione results in increased expression of AKR1D1 mRNA

NCBI chr 4:67,121,288...67,154,543
Ensembl chr 4:66,154,248...66,186,372

G

aldo-keto reductase family 7, member A2

increases expression

1,2-dithiol-3-thione results in increased expression of AKR7A2 mRNA

NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909

G

aldo-keto reductase family 7 member A3

increases expression

1,2-dithiol-3-thione results in increased expression of AKR7A3 mRNA; 1,2-dithiol-3-thione results in increased expression of AKR7A3 protein

PMID:19162173 PMID:19168568 PMID:19695238

NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394

G

5'-aminolevulinate synthase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of ALAS2 mRNA

PMID:15302862 PMID:19162173

NCBI chr X:19,463,146...19,486,526
Ensembl chr X:19,463,171...19,486,519

G

albumin

increases expression

1,2-dithiol-3-thione results in increased expression of ALB mRNA

NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836

G

activated leukocyte cell adhesion molecule

decreases expression

1,2-dithiol-3-thione results in decreased expression of ALCAM mRNA

NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954

G

aldehyde dehydrogenase 1 family, member A1

increases expression

1,2-dithiol-3-thione results in increased expression of ALDH1A1 mRNA

PMID:19162173 PMID:19695238

NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 1 family, member L1

increases expression

1,2-dithiol-3-thione results in increased expression of ALDH1L1 mRNA

NCBI chr 4:124,617,182...124,663,674
Ensembl chr 4:123,060,008...123,106,465

G

adenosylmethionine decarboxylase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of AMD1 mRNA

NCBI chr20:45,250,289...45,324,939
Ensembl chr20:43,697,237...43,711,476

G

ankyrin repeat and FYVE domain containing 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ANKFY1 mRNA

NCBI chr10:57,312,246...57,383,964
Ensembl chr10:57,312,246...57,383,964

G

annexin A1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ANXA1 mRNA

NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:217,861,175...217,877,343

G

annexin A3

decreases expression

1,2-dithiol-3-thione results in decreased expression of ANXA3 mRNA

NCBI chr14:13,031,675...13,085,678
Ensembl chr14:12,719,795...12,781,617

G

annexin A4

decreases expression

1,2-dithiol-3-thione results in decreased expression of ANXA4 mRNA

NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161

G

annexin A5

decreases expression

1,2-dithiol-3-thione results in decreased expression of ANXA5 mRNA

NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:119,314,007...119,353,369

G

adaptor related protein complex 2 subunit sigma 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of AP2S1 mRNA

NCBI chr 1:86,545,601...86,557,007
Ensembl chr 1:77,417,477...77,428,905

G

adaptor related protein complex 3 subunit mu 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of AP3M1 mRNA

NCBI chr15:3,285,591...3,314,139
Ensembl chr15:3,246,926...3,264,844

G

amyloid beta precursor protein binding family B member 1

increases expression

1,2-dithiol-3-thione results in increased expression of APBB1 mRNA

NCBI chr 1:169,308,719...169,332,372
Ensembl chr 1:159,896,880...159,920,627

G

amyloid P component, serum

decreases expression

1,2-dithiol-3-thione results in decreased expression of APCS mRNA

NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298

G

apurinic/apyrimidinic endodeoxyribonuclease 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of APEX1 mRNA

NCBI chr15:26,618,146...26,620,330
Ensembl chr15:24,144,362...24,146,785

G

apolipoprotein E

increases expression

1,2-dithiol-3-thione results in increased expression of APOE mRNA

NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932

G

amyloid beta precursor protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of APP mRNA

NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561

G

aquaporin 6

increases expression

1,2-dithiol-3-thione results in increased expression of AQP6 mRNA

NCBI chr 7:130,732,216...130,735,149
Ensembl chr 7:130,633,579...130,735,194
Ensembl chr 7:130,633,579...130,735,194

G

aquaporin 8

increases expression

1,2-dithiol-3-thione results in increased expression of AQP8 mRNA

NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158

G

ARF GTPase 6

decreases expression

1,2-dithiol-3-thione results in decreased expression of ARF6 mRNA

NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114

G

ARF like GTPase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ARL1 mRNA

NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898

G

ARF like GTPase 5A

decreases expression

1,2-dithiol-3-thione results in decreased expression of ARL5A mRNA

NCBI chr 3:36,878,461...36,903,362
Ensembl chr 3:36,880,712...36,903,211

G

ARF like GTPase 6 interacting protein 6

decreases expression

1,2-dithiol-3-thione results in decreased expression of ARL6IP6 mRNA

NCBI chr 3:37,689,994...37,720,358
Ensembl chr 3:37,690,382...37,718,018

G

actin related protein 2/3 complex, subunit 1B

decreases expression

1,2-dithiol-3-thione results in decreased expression of ARPC1B mRNA

NCBI chr12:9,482,176...9,495,772
Ensembl chr12:9,480,831...9,495,747

G

N-acylsphingosine amidohydrolase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ASAH1 mRNA

NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233

G

ATCAY kinesin light chain interacting caytaxin

decreases expression

1,2-dithiol-3-thione results in decreased expression of ATCAY mRNA

NCBI chr 7:8,487,763...8,511,527
Ensembl chr 7:8,487,763...8,512,663

G

arginyltransferase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ATE1 mRNA

NCBI chr 1:184,961,548...185,081,112
Ensembl chr 1:184,963,562...185,080,908

G

activating transcription factor 4

multiple interactions

1,2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of ATF4 mRNA]

NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:111,804,183...111,806,446

G

activating transcription factor 6

multiple interactions

1,2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of ATF6 mRNA]

NCBI chr13:85,460,312...85,639,959
Ensembl chr13:82,930,034...83,107,177

G

ATPase Na+/K+ transporting subunit beta 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ATP1B1 mRNA

NCBI chr13:79,319,708...79,340,226
Ensembl chr13:76,786,578...76,807,459

G

ATPase Na+/K+ transporting subunit beta 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of ATP1B3 mRNA

NCBI chr 8:105,789,824...105,821,151
Ensembl chr 8:96,910,309...96,941,598
Ensembl chr 8:96,910,309...96,941,598

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1

increases expression

1,2-dithiol-3-thione results in increased expression of ATP2A1 mRNA

NCBI chr 1:190,457,198...190,475,410
Ensembl chr 1:181,026,608...181,044,838

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of ATP2A2 mRNA

NCBI chr12:39,733,519...39,782,942
Ensembl chr12:34,072,683...34,122,101

G

ATPase secretory pathway Ca2+ transporting 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ATP2C1 mRNA

NCBI chr 8:106,034,777...106,155,854
Ensembl chr 8:106,034,636...106,156,006

G

ATP synthase peripheral stalk subunit OSCP

increases expression

1,2-dithiol-3-thione results in increased expression of ATP5PO mRNA

NCBI chr11:44,651,171...44,657,483
Ensembl chr11:31,165,217...31,171,592

G

ATPase H+ transporting accessory protein 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ATP6AP1 mRNA

NCBI chr X:157,231,243...157,238,323
Ensembl chr X:152,079,865...152,087,034

G

ATPase H+ transporting V1 subunit D

decreases expression

1,2-dithiol-3-thione results in decreased expression of ATP6V1D mRNA

NCBI chr 6:103,389,778...103,405,346
Ensembl chr 6:97,656,576...97,672,303

G

arginine vasopressin receptor 1A

decreases expression

1,2-dithiol-3-thione results in decreased expression of AVPR1A mRNA

NCBI chr 7:59,999,743...60,003,667
Ensembl chr 7:58,114,284...58,122,215

G

antizyme inhibitor 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of AZIN1 mRNA

NCBI chr 7:71,539,711...71,566,515
Ensembl chr 7:69,654,663...69,681,578

G

BCL2-associated transcription factor 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of BCLAF1 mRNA

NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832

G

brain-derived neurotrophic factor

increases expression

1,2-dithiol-3-thione results in increased expression of BDNF mRNA

NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615

G

beclin 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of BECN1 mRNA

NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742

G

Bet1 golgi vesicular membrane trafficking protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of BET1 mRNA

NCBI chr 4:32,116,232...32,126,592
Ensembl chr 4:32,116,235...32,126,617

G

betaine-homocysteine S-methyltransferase

increases expression

1,2-dithiol-3-thione results in increased expression of BHMT mRNA

NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:24,859,873...24,879,742

G

BCL2 interacting protein 3 like

decreases expression

1,2-dithiol-3-thione results in decreased expression of BNIP3L mRNA

NCBI chr15:45,350,081...45,373,213
Ensembl chr15:41,174,594...41,197,803

G

3'(2'), 5'-bisphosphate nucleotidase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of BPNT1 mRNA

NCBI chr13:99,397,127...99,425,056
Ensembl chr13:96,868,580...96,893,503

G

BRCA1/BRCA2-containing complex subunit 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of BRCC3 mRNA

NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080

G

biotinidase

decreases expression

1,2-dithiol-3-thione results in decreased expression of BTD mRNA

NCBI chr16:6,869,448...6,900,711
Ensembl chr16:6,862,407...6,940,945

G

BTG anti-proliferation factor 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of BTG1 mRNA

NCBI chr 7:33,228,149...33,230,406
Ensembl chr 7:31,341,027...31,343,649

G

C1D nuclear receptor corepressor

decreases expression

1,2-dithiol-3-thione results in decreased expression of C1D mRNA

NCBI chr14:91,660,951...91,673,177
Ensembl chr14:91,660,989...91,672,852

G

complement C1q B chain

decreases expression

1,2-dithiol-3-thione results in decreased expression of C1QB mRNA

NCBI chr 5:154,402,276...154,407,827
Ensembl chr 5:149,118,846...149,124,407

G

complement C1q C chain

decreases expression

1,2-dithiol-3-thione results in decreased expression of C1QC mRNA

NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:149,127,415...149,131,017

G

complement C1s

decreases expression

1,2-dithiol-3-thione results in decreased expression of C1S mRNA

NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:157,430,117...157,442,303

G

complement component 4 binding protein, beta

decreases expression

1,2-dithiol-3-thione results in decreased expression of C4BPB mRNA

NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817

G

calcium voltage-gated channel subunit alpha1 D

decreases expression

1,2-dithiol-3-thione results in decreased expression of CACNA1D mRNA

NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,228,306...5,668,215

G

calcium dependent secretion activator 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of CADPS2 mRNA

NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829

G

calbindin 1

increases expression

1,2-dithiol-3-thione results in increased expression of CALB1 mRNA

NCBI chr 5:34,172,612...34,199,555
Ensembl chr 5:29,375,642...29,402,431

G

calmodulin 1

increases expression

1,2-dithiol-3-thione results in increased expression of CALM1 mRNA

NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:119,487,621...119,498,227

G

calcium/calmodulin-dependent protein kinase II delta

increases expression

1,2-dithiol-3-thione results in increased expression of CAMK2D mRNA

NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:215,024,004...215,286,178

G

cullin-associated and neddylation-dissociated 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CAND1 mRNA

NCBI chr 7:54,681,114...54,719,002
Ensembl chr 7:54,680,900...54,718,993

G

calnexin

decreases expression

1,2-dithiol-3-thione results in decreased expression of CANX mRNA

NCBI chr10:35,124,941...35,157,954
Ensembl chr10:34,625,191...34,656,821

G

calpain 1

increases expression

1,2-dithiol-3-thione results in increased expression of CAPN1 mRNA

NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:203,277,344...203,300,177

G

calpain 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of CAPN2 mRNA

NCBI chr13:96,681,902...96,732,625
Ensembl chr13:94,150,240...94,200,969

G

calpain, small subunit 1

increases expression

1,2-dithiol-3-thione results in increased expression of CAPNS1 mRNA

NCBI chr 1:85,444,613...85,454,861
Ensembl chr 1:85,444,608...85,454,795

G

capping actin protein of muscle Z-line subunit alpha 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of CAPZA2 mRNA

NCBI chr 4:45,978,142...46,014,032
Ensembl chr 4:45,977,807...46,013,864

G

carbonic anhydrase 2

increases expression

1,2-dithiol-3-thione results in increased expression of CA2 mRNA

NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:86,741,626...86,756,818

G

carbonic anhydrase 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of CAR3 mRNA

PMID:15302862 PMID:19162173

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

carbonic anhydrase 5A

increases expression

1,2-dithiol-3-thione results in increased expression of CA5A mRNA

NCBI chr19:49,973,092...50,002,948
Ensembl chr19:49,973,107...50,002,906

G

calcium/calmodulin dependent serine protein kinase

decreases expression

1,2-dithiol-3-thione results in decreased expression of CASK mRNA

NCBI chr X:8,899,500...9,243,014
Ensembl chr X:8,899,833...9,238,694

G

caspase 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of CASP3 mRNA

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648

G

caspase 6

decreases expression

1,2-dithiol-3-thione results in decreased expression of CASP6 mRNA

NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:218,466,076...218,478,502

G

calpastatin

decreases expression

1,2-dithiol-3-thione results in decreased expression of CAST mRNA

NCBI chr 2:5,707,633...5,817,213
Ensembl chr 2:3,973,112...4,082,659

G

catalase

increases activity
increases expression
multiple interactions

1,2-dithiol-3-thione results in increased activity of CAT protein
1,2-dithiol-3-thione results in increased expression of CAT mRNA; 1,2-dithiol-3-thione results in increased expression of CAT protein
NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased activity of CAT protein]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of CAT mRNA]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of CAT protein]

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478

G

caveolae associated protein 3

increases expression

1,2-dithiol-3-thione results in increased expression of CAVIN3 mRNA

NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161

G

core-binding factor subunit beta

decreases expression

1,2-dithiol-3-thione results in decreased expression of CBFB mRNA

NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751

G

cholecystokinin

increases expression

1,2-dithiol-3-thione results in increased expression of CCK mRNA

NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:121,153,500...121,160,084

G

cholecystokinin A receptor

increases expression

1,2-dithiol-3-thione results in increased expression of CCKAR mRNA

NCBI chr14:61,505,270...61,513,618
Ensembl chr14:57,292,397...57,300,747

G

C-C motif chemokine ligand 2

increases expression

1,2-dithiol-3-thione results in increased expression of CCL2 mRNA

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of CCL3 mRNA

NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,451,388...68,452,938

G

C-C motif chemokine ligand 5

decreases expression

1,2-dithiol-3-thione results in decreased expression of CCL5 mRNA

NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377

G

cyclin D1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CCND1 mRNA

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602

G

cyclin G1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CCNG1 mRNA

NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,176,234...25,181,641

G

cyclin L1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CCNL1 mRNA

NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368

G

chaperonin containing TCP1 subunit 3

increases expression

1,2-dithiol-3-thione results in increased expression of CCT3 mRNA

NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757

G

chaperonin containing TCP1 subunit 7

increases expression

1,2-dithiol-3-thione results in increased expression of CCT7 mRNA

NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580

G

CD36 molecule

increases expression

1,2-dithiol-3-thione results in increased expression of CD36 mRNA

NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903

G

CD38 molecule

decreases expression

1,2-dithiol-3-thione results in decreased expression of CD38 mRNA

NCBI chr14:71,384,532...71,424,794
Ensembl chr14:67,172,063...67,211,986

G

Cd47 molecule

decreases expression

1,2-dithiol-3-thione results in decreased expression of CD47 mRNA

NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425

G

Cd48 molecule

decreases expression

1,2-dithiol-3-thione results in decreased expression of CD48 mRNA

NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142

G

Cd53 molecule

decreases expression

1,2-dithiol-3-thione results in decreased expression of CD53 mRNA

NCBI chr 2:197,040,369...197,087,925
Ensembl chr 2:194,352,139...194,399,657

G

Cd63 molecule

decreases expression

1,2-dithiol-3-thione results in decreased expression of CD63 mRNA

NCBI chr 7:1,909,538...1,924,937
Ensembl chr 7:1,325,103...1,399,178

G

CD74 molecule

decreases expression

1,2-dithiol-3-thione results in decreased expression of CD74 mRNA

NCBI chr18:56,527,071...56,536,406
Ensembl chr18:54,256,778...54,266,003

G

CD86 molecule

decreases expression

1,2-dithiol-3-thione results in decreased expression of CD86 mRNA

NCBI chr11:77,647,565...77,706,178
Ensembl chr11:64,163,828...64,200,818

G

CDC42 binding protein kinase beta

increases expression

1,2-dithiol-3-thione results in increased expression of CDC42BPB mRNA

NCBI chr 6:130,333,712...130,416,631
Ensembl chr 6:130,333,712...130,416,377

G

cadherin 17

decreases expression

1,2-dithiol-3-thione results in decreased expression of CDH17 mRNA

NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884

G

cyclin-dependent kinase 5

increases expression

1,2-dithiol-3-thione results in increased expression of CDK5 mRNA

NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:10,754,687...10,760,112

G

CCAAT/enhancer binding protein alpha

increases expression

1,2-dithiol-3-thione results in increased expression of CEBPA mRNA

NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:87,759,433...87,762,412

G

CCAAT/enhancer binding protein beta

decreases expression

1,2-dithiol-3-thione results in decreased expression of CEBPB mRNA

NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:156,397,052...156,399,473

G

chymotrypsin like elastase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CELA1 mRNA

NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285

G

choline/ethanolamine phosphotransferase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CEPT1 mRNA

NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578

G

complement factor D

decreases expression

1,2-dithiol-3-thione results in decreased expression of CFD mRNA

NCBI chr 7:10,463,773...10,465,496
Ensembl chr 7:9,813,150...9,815,053

G

cofilin 1

increases expression

1,2-dithiol-3-thione results in increased expression of CFL1 mRNA

NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:202,786,627...202,817,587

G

complement factor properdin

decreases expression

1,2-dithiol-3-thione results in decreased expression of CFP mRNA

NCBI chr X:3,715,551...3,721,113
Ensembl chr X:1,161,979...1,167,573

G

cell growth regulator with ring finger domain 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CGRRF1 mRNA

NCBI chr15:20,088,564...20,109,042
Ensembl chr15:20,088,571...20,109,037

G

coiled-coil-helix-coiled-coil-helix domain containing 6

increases expression

1,2-dithiol-3-thione results in increased expression of CHCHD6 mRNA

NCBI chr 4:121,803,501...122,024,209
Ensembl chr 4:121,792,717...122,024,216

G

chimerin 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of CHN2 mRNA

NCBI chr 4:83,148,616...83,407,711
Ensembl chr 4:83,147,983...83,407,709

G

cysteine and histidine rich domain containing 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CHORDC1 mRNA

NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162

G

cholinergic receptor nicotinic alpha 3 subunit

increases expression

1,2-dithiol-3-thione results in increased expression of CHRNA3 mRNA

NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:55,401,702...55,415,165

G

cholinergic receptor nicotinic delta subunit

increases expression

1,2-dithiol-3-thione results in increased expression of CHRND mRNA

NCBI chr 9:95,310,316...95,318,734
Ensembl chr 9:87,862,407...87,870,833

G

churchill domain containing 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CHURC1 mRNA

NCBI chr 6:95,464,488...95,485,208
Ensembl chr 6:95,470,683...95,619,586

G

cytosolic iron-sulfur assembly component 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CIAO1 mRNA

NCBI chr 3:114,458,671...114,465,928
Ensembl chr 3:114,458,655...114,467,009

G

CBY1 interacting BAR domain containing 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CIBAR1 mRNA

NCBI chr 5:25,613,993...25,632,440
Ensembl chr 5:25,614,033...25,632,489

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of CITED2 mRNA

NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897

G

C-type lectin domain family 4, member F

decreases expression

1,2-dithiol-3-thione results in decreased expression of CLEC4F mRNA

NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775

G

CKLF-like MARVEL transmembrane domain containing 6

decreases expression

1,2-dithiol-3-thione results in decreased expression of CMTM6 mRNA

NCBI chr 8:114,422,934...114,441,034
Ensembl chr 8:114,422,921...114,441,033

G

CCHC-type zinc finger, nucleic acid binding protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of CNBP mRNA

NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637

G

calponin 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of CNN3 mRNA

NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104

G

collagen type I alpha 1 chain

decreases expression

1,2-dithiol-3-thione results in decreased expression of COL1A1 mRNA

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624

G

collagen type III alpha 1 chain

decreases expression

1,2-dithiol-3-thione results in decreased expression of COL3A1 mRNA

NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:47,374,593...47,410,547

G

collagen type V alpha 2 chain

decreases expression

1,2-dithiol-3-thione results in decreased expression of COL5A2 mRNA

NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:47,448,736...47,598,154

G

COPI coat complex subunit beta 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of COPB2 mRNA

NCBI chr 8:99,161,324...99,183,452
Ensembl chr 8:99,161,350...99,185,197

G

coronin 1A

decreases expression

1,2-dithiol-3-thione results in decreased expression of CORO1A mRNA

NCBI chr 1:190,726,129...190,731,133
Ensembl chr 1:181,295,562...181,300,534

G

cytochrome c oxidase subunit 5B

decreases expression

1,2-dithiol-3-thione results in decreased expression of COX5B mRNA

NCBI chr 9:46,417,735...46,419,664
Ensembl chr 9:38,921,967...38,925,052

G

cytochrome c oxidase subunit 6B1

increases expression

1,2-dithiol-3-thione results in increased expression of COX6B1 mRNA

NCBI chr 1:95,002,513...95,011,516
Ensembl chr 1:85,875,109...85,884,001
Ensembl chr 2:85,875,109...85,884,001
Ensembl chr 5:85,875,109...85,884,001

G

cytochrome c oxidase subunit 6C

increases expression

1,2-dithiol-3-thione results in increased expression of COX6C mRNA

NCBI chr 7:69,014,410...69,027,145
Ensembl chr 7:67,111,024...67,141,963

G

ceruloplasmin

decreases expression

1,2-dithiol-3-thione results in decreased expression of CP mRNA

NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:102,439,624...102,498,075

G

carboxypeptidase Q

decreases expression

1,2-dithiol-3-thione results in decreased expression of CPQ mRNA

NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546

G

cleavage and polyadenylation specific factor 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of CPSF2 mRNA

NCBI chr 6:121,123,941...121,152,756
Ensembl chr 6:121,120,569...121,151,921

G

cellular repressor of E1A-stimulated genes 1

increases expression

1,2-dithiol-3-thione results in increased expression of CREG1 mRNA

NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308

G

cysteine-rich with EGF-like domains 2

increases expression

1,2-dithiol-3-thione results in increased expression of CRELD2 mRNA

NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543

G

CXXC repeat containing interactor of PDZ3 domain

decreases expression

1,2-dithiol-3-thione results in decreased expression of CRIPT mRNA

NCBI chr 6:7,581,428...7,589,384
Ensembl chr 6:7,580,703...7,589,399

G

carnitine O-octanoyltransferase

decreases expression

1,2-dithiol-3-thione results in decreased expression of CROT mRNA

NCBI chr 4:26,031,729...26,088,057
Ensembl chr 4:25,080,587...25,133,109

G

C-reactive protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of CRP mRNA

NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178

G

crystallin zeta

increases expression

1,2-dithiol-3-thione results in increased expression of CRYZ

NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758

G

cold shock domain containing E1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CSDE1 mRNA

NCBI chr 2:190,546,015...190,582,787
Ensembl chr 2:190,554,980...190,582,784

G

casein kappa

increases expression

1,2-dithiol-3-thione results in increased expression of CSN3 mRNA

NCBI chr14:20,154,032...20,160,585
Ensembl chr14:20,154,032...20,160,587

G

cystatin B

decreases expression

1,2-dithiol-3-thione results in decreased expression of CSTB mRNA

NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526

G

C-terminal binding protein 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CTBP1 mRNA

NCBI chr14:81,679,956...81,707,331
Ensembl chr14:77,455,696...77,482,821

G

cystathionine gamma-lyase

increases expression

1,2-dithiol-3-thione results in increased expression of CTH mRNA

NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:246,975,894...247,002,234

G

cytotoxic T-lymphocyte-associated protein 4

increases expression

1,2-dithiol-3-thione results in increased expression of CTLA4 mRNA

NCBI chr 9:69,812,859...69,819,959
Ensembl chr 9:62,319,312...62,324,963

G

chymotrypsin C

increases expression

1,2-dithiol-3-thione results in increased expression of CTRC mRNA

NCBI chr 5:154,147,314...154,156,540
Ensembl chr 5:154,147,316...154,156,528

G

cathepsin L

decreases expression

1,2-dithiol-3-thione results in decreased expression of CTSL mRNA

NCBI chr17:770,104...776,266
Ensembl chr17:764,309...770,548

G

cathepsin S

decreases expression

1,2-dithiol-3-thione results in decreased expression of CTSS mRNA

NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:183,086,437...183,114,483

G

C-X-C motif chemokine receptor 5

decreases expression

1,2-dithiol-3-thione results in decreased expression of CXCR5 mRNA

NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893

G

CXXC finger protein 5

increases expression

1,2-dithiol-3-thione results in increased expression of CXXC5 mRNA

NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,427,230...27,458,673

G

cytochrome b5 reductase 3

increases expression

1,2-dithiol-3-thione results in increased expression of CYB5R3 mRNA

NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298

G

cytochrome b-245 alpha chain

decreases expression

1,2-dithiol-3-thione results in decreased expression of CYBA mRNA

NCBI chr19:67,396,143...67,404,214
Ensembl chr19:50,487,597...50,495,721

G

cytochrome c, somatic

decreases expression

1,2-dithiol-3-thione results in decreased expression of CYCS mRNA

NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytochrome P450, family 17, subfamily a, polypeptide 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CYP17A1 mRNA

NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 1, subfamily a, polypeptide 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of CYP1A2 mRNA

NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 2, subfamily a, polypeptide 1

increases expression

1,2-dithiol-3-thione results in increased expression of CYP2A1 mRNA

NCBI chr 1:91,359,278...91,372,554
Ensembl chr 1:82,231,611...82,244,887

G

cytochrome P450, family 2, subfamily b, polypeptide 15

increases expression

1,2-dithiol-3-thione results in increased expression of CYP2B15 mRNA

NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492

G

cytochrome P450, family 2, subfamily b, polypeptide 2

increases expression

1,2-dithiol-3-thione results in increased expression of CYP2B2 mRNA

NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566

G

cytochrome P450, family 2, subfamily b, polypeptide 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of CYP2B3 mRNA

NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily j, polypeptide 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of CYP2J3 mRNA

NCBI chr 5:111,219,921...111,244,987
Ensembl chr 5:111,178,703...111,244,794

G

cytochrome P450, family 3, subfamily a, polypeptide 18

increases expression

1,2-dithiol-3-thione results in increased expression of CYP3A18 mRNA

NCBI chr12:13,994,312...14,044,185
Ensembl chr12:8,880,528...8,930,381

G

cytochrome P450, family 3, subfamily a, polypeptide 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of CYP3A2 mRNA

NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CYP3A23-3A1 mRNA

NCBI chr12:14,369,950...14,398,803
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030

G

cytochrome P450, family 4, subfamily b, polypeptide 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CYP4B1 mRNA

NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348

G

cytochrome P450, family 51

decreases expression

1,2-dithiol-3-thione results in decreased expression of CYP51 mRNA

NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410

G

cytochrome P450 family 7 subfamily B member 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of CYP7B1 mRNA

NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:100,502,791...100,669,698

G

dishevelled-binding antagonist of beta-catenin 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of DACT2 mRNA

NCBI chr 1:55,181,023...55,191,026
Ensembl chr 1:55,181,024...55,191,096

G

death-associated protein kinase 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of DAPK3 mRNA

NCBI chr 7:9,174,903...9,183,272
Ensembl chr 7:8,524,183...8,532,558

G

aspartyl-tRNA synthetase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of DARS1 mRNA

NCBI chr13:42,410,351...42,465,467
Ensembl chr13:39,857,936...39,913,116

G

D-box binding PAR bZIP transcription factor

decreases expression

1,2-dithiol-3-thione results in decreased expression of DBP mRNA

NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745

G

DDB1 and CUL4 associated factor 6

decreases expression

1,2-dithiol-3-thione results in decreased expression of DCAF6 mRNA

NCBI chr13:77,626,257...77,727,645
Ensembl chr13:77,626,307...77,727,512

G

dephospho-CoA kinase domain containing

increases expression

1,2-dithiol-3-thione results in increased expression of DCAKD mRNA

NCBI chr10:88,457,829...88,489,011
Ensembl chr10:87,957,740...87,980,054

G

decorin

decreases expression

1,2-dithiol-3-thione results in decreased expression of DCN mRNA

NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:32,281,252...32,321,270

G

dimethylarginine dimethylaminohydrolase 1

increases expression

1,2-dithiol-3-thione results in increased expression of DDAH1 mRNA

NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339

G

DNA-damage inducible transcript 3

multiple interactions

1,2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of DDIT3 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [1,2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of DDIT3 mRNA]]; Bortezomib inhibits the reaction [1,2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of DDIT3 mRNA]]

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201

G

D-dopachrome tautomerase

increases expression

1,2-dithiol-3-thione results in increased expression of DDT mRNA

NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482

G

DExD-box helicase 21

decreases expression

1,2-dithiol-3-thione results in decreased expression of DDX21 mRNA

NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543

G

DEAD-box helicase 3, X-linked

decreases expression

1,2-dithiol-3-thione results in decreased expression of DDX3X mRNA

NCBI chr X:12,152,346...12,165,983
Ensembl chr X:9,479,532...9,493,168

G

DEAD-box helicase 42

decreases expression

1,2-dithiol-3-thione results in decreased expression of DDX42 mRNA

NCBI chr10:91,148,926...91,180,940
Ensembl chr10:91,148,254...91,180,939

G

DEAD-box helicase 46

decreases expression

1,2-dithiol-3-thione results in decreased expression of DDX46 mRNA

NCBI chr17:8,942,070...8,988,440
Ensembl chr17:8,944,454...8,988,439

G

DExD-box helicase 50

decreases expression

1,2-dithiol-3-thione results in decreased expression of DDX50 mRNA

NCBI chr20:30,561,623...30,591,324
Ensembl chr20:30,560,544...30,591,152

G

7-dehydrocholesterol reductase

decreases expression

1,2-dithiol-3-thione results in decreased expression of DHCR7 mRNA

NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055

G

DExH-box helicase 9

decreases expression

1,2-dithiol-3-thione results in decreased expression of DHX9 mRNA

NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069

G

iodothyronine deiodinase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of DIO1 mRNA

NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970

G

DLG associated protein 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of DLGAP4 mRNA

NCBI chr 3:145,124,189...145,271,791
Ensembl chr 3:145,175,479...145,270,490

G

delta like canonical Notch ligand 1

increases expression

1,2-dithiol-3-thione results in increased expression of DLL1 mRNA

NCBI chr 1:64,985,161...64,993,274
Ensembl chr 1:56,312,066...56,320,179

G

cyclin D binding myb-like transcription factor 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of DMTF1 mRNA

NCBI chr 4:24,909,937...24,950,786
Ensembl chr 4:24,910,534...24,950,967

G

dynein, axonemal, heavy chain 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of DNAH1 mRNA

NCBI chr16:6,462,419...6,523,545
Ensembl chr16:6,456,002...6,518,350

G

dynein, axonemal, heavy chain 6

increases expression

1,2-dithiol-3-thione results in increased expression of DNAH6 mRNA

NCBI chr 4:105,064,123...105,284,361
Ensembl chr 4:105,064,125...105,284,376

G

DnaJ heat shock protein family (Hsp40) member A1

decreases expression

1,2-dithiol-3-thione results in decreased expression of DNAJA1 mRNA

NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967

G

DnaJ heat shock protein family (Hsp40) member A2

decreases expression

1,2-dithiol-3-thione results in decreased expression of DNAJA2 mRNA

NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901

G

DnaJ heat shock protein family (Hsp40) member B11

increases expression

1,2-dithiol-3-thione results in increased expression of DNAJB11 mRNA

NCBI chr11:91,656,334...91,672,800
Ensembl chr11:78,150,429...78,180,407

G

DnaJ heat shock protein family (Hsp40) member B9

decreases expression
increases expression

1,2-dithiol-3-thione results in decreased expression of DNAJB9 mRNA
1,2-dithiol-3-thione results in increased expression of DNAJB9 mRNA

PMID:15375163 PMID:19162173

NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063

G

dynamin 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of DNM2 mRNA

NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157

G

dedicator of cytokinesis 8

decreases expression

1,2-dithiol-3-thione results in decreased expression of DOCK8 mRNA

NCBI chr 1:232,075,468...232,268,830
Ensembl chr 1:222,649,309...222,842,474

G

dedicator of cytokinesis 9

decreases expression

1,2-dithiol-3-thione results in decreased expression of DOCK9 mRNA

NCBI chr15:98,611,518...98,883,306
Ensembl chr15:98,618,084...98,883,153

G

dipeptidylpeptidase 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of DPP4 mRNA

NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:46,962,243...47,043,901

G

dihydropyrimidine dehydrogenase

decreases expression

1,2-dithiol-3-thione results in decreased expression of DPYD mRNA

NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:206,609,122...207,474,982

G

D-aminoacyl-tRNA deacylase 1

increases expression

1,2-dithiol-3-thione results in increased expression of DTD1 mRNA

NCBI chr 3:131,995,870...132,158,646
Ensembl chr 3:131,995,861...132,158,659

G

dynein cytoplasmic 1 intermediate chain 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of DYNC1I2 mRNA

NCBI chr 3:76,441,621...76,492,782
Ensembl chr 3:56,033,917...56,085,080

G

EBP, cholestenol delta-isomerase

decreases expression

1,2-dithiol-3-thione results in decreased expression of EBP mRNA

NCBI chr X:16,971,372...16,977,782
Ensembl chr X:14,299,448...14,305,826

G

enoyl-CoA hydratase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ECH1 mRNA

NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:84,112,751...84,120,795

G

endothelin 1

increases expression

1,2-dithiol-3-thione results in increased expression of EDN1 mRNA

NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,454,420...22,460,885

G

endothelin 3

increases expression

1,2-dithiol-3-thione results in increased expression of EDN3 mRNA

NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093

G

endothelin receptor type B

decreases expression

1,2-dithiol-3-thione results in decreased expression of EDNRB mRNA

NCBI chr15:87,055,490...87,086,765
Ensembl chr15:80,643,043...80,672,115

G

eukaryotic translation elongation factor 1 alpha 1

increases expression

1,2-dithiol-3-thione results in increased expression of EEF1A1 mRNA

NCBI chr 8:88,221,839...88,225,688
Ensembl chr 8:79,341,557...79,344,839

G

eukaryotic translation elongation factor 2

increases expression

1,2-dithiol-3-thione results in increased expression of EEF2 mRNA

NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:8,533,116...8,559,183

G

ephrin A1

decreases expression

1,2-dithiol-3-thione results in decreased expression of EFNA1 mRNA

NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866

G

EGF-like-domain, multiple 7

decreases expression

1,2-dithiol-3-thione results in decreased expression of EGFL7 mRNA

NCBI chr 3:9,404,622...9,416,879
Ensembl chr 3:9,407,520...9,416,879

G

epidermal growth factor receptor

decreases expression

1,2-dithiol-3-thione results in decreased expression of EGFR mRNA

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382

G

early growth response 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of EGR1 mRNA

NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766

G

enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

decreases expression

1,2-dithiol-3-thione results in decreased expression of EHHADH mRNA

NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188

G

EP300 interacting inhibitor of differentiation 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of EID1 mRNA

NCBI chr 3:112,922,961...112,924,680
Ensembl chr 3:112,922,668...112,924,752

G

eukaryotic translation initiation factor 2-alpha kinase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of EIF2AK2 mRNA

NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:16,188,979...16,224,971

G

eukaryotic translation initiation factor 2 alpha kinase 3

decreases expression
multiple interactions

1,2-dithiol-3-thione results in decreased expression of EIF2AK3 mRNA
1,2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of EIF2AK3 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [1,2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of EIF2AK3 mRNA]]; Bortezomib inhibits the reaction [1,2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of EIF2AK3 mRNA]]

PMID:19162173 PMID:22959925

NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911

G

eukaryotic translation initiation factor 3, subunit C

increases expression

1,2-dithiol-3-thione results in increased expression of EIF3C mRNA

NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493

G

eukaryotic translation initiation factor 3, subunit D

increases expression

1,2-dithiol-3-thione results in increased expression of EIF3D mRNA

NCBI chr 7:109,539,795...109,552,184
Ensembl chr 7:109,539,356...109,552,206

G

eukaryotic translation initiation factor 3 subunit E

increases expression

1,2-dithiol-3-thione results in increased expression of EIF3E mRNA

NCBI chr 7:76,224,567...76,257,346
Ensembl chr 7:74,339,828...74,373,096

G

eukaryotic translation initiation factor 4E

decreases expression

1,2-dithiol-3-thione results in decreased expression of EIF4E mRNA

NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683

G

eukaryotic translation initiation factor 4, gamma 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of EIF4G2 mRNA

NCBI chr 1:174,616,102...174,628,252
Ensembl chr 1:165,181,434...165,193,588

G

eukaryotic translation initiation factor 5B

decreases expression

1,2-dithiol-3-thione results in decreased expression of EIF5B mRNA

NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482

G

eukaryotic translation initiation factor 6

increases expression

1,2-dithiol-3-thione results in increased expression of EIF6 mRNA

NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401

G

ER membrane protein complex subunit 8

decreases expression

1,2-dithiol-3-thione results in decreased expression of EMC8 mRNA

NCBI chr19:48,708,304...48,721,626
Ensembl chr19:48,582,574...48,721,543

G

enolase 1

increases expression

1,2-dithiol-3-thione results in increased expression of ENO1 mRNA

NCBI chr 5:166,002,867...166,014,252
Ensembl chr 5:160,719,951...160,731,336
Ensembl chr 3:160,719,951...160,731,336

G

enolase 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of ENO3 mRNA

NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921

G

glutamyl aminopeptidase

decreases expression

1,2-dithiol-3-thione results in decreased expression of ENPEP mRNA

NCBI chr 2:220,456,258...220,526,218
Ensembl chr 2:217,782,005...217,851,947

G

epoxide hydrolase 1

increases expression

1,2-dithiol-3-thione results in increased expression of EPHX1 mRNA

PMID:19162173 PMID:19695238

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

erb-b2 receptor tyrosine kinase 2

increases expression

1,2-dithiol-3-thione results in increased expression of ERBB2 mRNA

NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,411,313...83,435,078

G

endoplasmic reticulum to nucleus signaling 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ERN1 mRNA

NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029

G

endoplasmic reticulum protein 29

increases expression

1,2-dithiol-3-thione results in increased expression of ERP29 mRNA

NCBI chr12:40,750,177...40,756,607
Ensembl chr12:35,089,707...35,096,376

G

electron transfer flavoprotein subunit alpha

decreases expression

1,2-dithiol-3-thione results in decreased expression of ETFA mRNA

NCBI chr 8:64,731,192...64,787,965
Ensembl chr 8:55,835,134...55,891,969

G

electron transfer flavoprotein dehydrogenase

decreases expression

1,2-dithiol-3-thione results in decreased expression of ETFDH mRNA

NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745

G

ETS proto-oncogene 1, transcription factor

decreases expression

1,2-dithiol-3-thione results in decreased expression of ETS1 mRNA

NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:31,045,945...31,168,010

G

exocyst complex component 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of EXOC3 mRNA

NCBI chr 1:29,091,298...29,122,056
Ensembl chr 1:29,091,294...29,122,045

G

fatty acid binding protein 5

increases expression

1,2-dithiol-3-thione results in increased expression of FABP5 mRNA

NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773

G

fatty acid binding protein 7

decreases expression

1,2-dithiol-3-thione results in decreased expression of FABP7 mRNA

NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880

G

fatty acid synthase

increases expression
decreases expression

1,2-dithiol-3-thione results in increased expression of FASN mRNA
1,2-dithiol-3-thione results in decreased expression of FASN mRNA

PMID:15302862 PMID:19162173

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261

G

fibulin 5

decreases expression

1,2-dithiol-3-thione results in decreased expression of FBLN5 mRNA

NCBI chr 6:120,899,219...120,977,829
Ensembl chr 6:120,899,224...120,977,755

G

fructose-bisphosphatase 2

increases expression

1,2-dithiol-3-thione results in increased expression of FBP2 mRNA

NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698

G

F-box protein 38

decreases expression

1,2-dithiol-3-thione results in decreased expression of FBXO38 mRNA

NCBI chr18:55,956,950...56,004,013
Ensembl chr18:55,956,959...56,003,961

G

Fc gamma receptor 2B

decreases expression

1,2-dithiol-3-thione results in decreased expression of FCGR2B mRNA

NCBI chr13:85,725,897...85,740,517
Ensembl chr13:83,193,163...83,207,778

G

Fc gamma receptor and transporter

decreases expression

1,2-dithiol-3-thione results in decreased expression of FCGRT mRNA

NCBI chr 1:95,574,436...95,584,171
Ensembl chr 1:95,567,175...95,584,084

G

farnesyl diphosphate farnesyl transferase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of FDFT1 mRNA

NCBI chr15:41,588,114...41,616,168
Ensembl chr15:37,412,146...37,440,287

G

farnesyl diphosphate synthase

decreases expression

1,2-dithiol-3-thione results in decreased expression of FDPS mRNA

PMID:15302862 PMID:19162173

NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:174,486,665...174,507,776

G

fibrinogen alpha chain

decreases expression

1,2-dithiol-3-thione results in decreased expression of FGA mRNA

NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:168,374,120...168,381,528

G

fibrinogen beta chain

decreases expression

1,2-dithiol-3-thione results in decreased expression of FGB mRNA

NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:168,394,916...168,405,979

G

fibroblast growth factor 2

increases expression

1,2-dithiol-3-thione results in increased expression of FGF2 mRNA

NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:120,236,328...120,291,221

G

fibroblast growth factor receptor 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of FGFR4 mRNA

NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242

G

fibrinogen gamma chain

decreases expression

1,2-dithiol-3-thione results in decreased expression of FGG mRNA

NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:168,355,013...168,362,322

G

fission, mitochondrial 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of FIS1 mRNA

NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377

G

FKBP prolyl isomerase 11

increases expression

1,2-dithiol-3-thione results in increased expression of FKBP11 mRNA

NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303

G

FKBP prolyl isomerase 1A

increases expression

1,2-dithiol-3-thione results in increased expression of FKBP1A mRNA

NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743

G

FKBP prolyl isomerase 4

increases expression

1,2-dithiol-3-thione results in increased expression of FKBP4 mRNA

NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833

G

FKBP prolyl isomerase 5

increases expression

1,2-dithiol-3-thione results in increased expression of FKBP5 mRNA

NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,457,216...6,541,674

G

filamin C

increases expression

1,2-dithiol-3-thione results in increased expression of FLNC mRNA

NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844

G

flavin containing dimethylaniline monoxygenase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of FMO1 mRNA

NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647

G

forkhead box A3

decreases expression

1,2-dithiol-3-thione results in decreased expression of FOXA3 mRNA

NCBI chr 1:87,790,111...87,800,259
Ensembl chr 1:78,662,431...78,672,155

G

forkhead box K2

decreases expression

1,2-dithiol-3-thione results in decreased expression of FOXK2 mRNA

NCBI chr10:106,542,643...106,592,569
Ensembl chr10:106,542,566...106,592,563

G

fyn-related Src family tyrosine kinase

decreases expression

1,2-dithiol-3-thione results in decreased expression of FRK mRNA

NCBI chr20:38,265,416...38,371,038
Ensembl chr20:38,265,280...38,371,114

G

ferritin light chain 1

increases expression

1,2-dithiol-3-thione results in increased expression of FTL1 mRNA

NCBI chr 1:105,072,858...105,074,705
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
Ensembl chr 2:95,936,387...95,939,725

G

FXYD domain-containing ion transport regulator 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of FXYD2 mRNA

NCBI chr 8:54,609,658...54,616,788
Ensembl chr 8:45,712,903...45,720,203

G

G0/G1switch 2

increases expression

1,2-dithiol-3-thione results in increased expression of G0S2 mRNA

NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451

G

glucose-6-phosphate dehydrogenase

increases expression

1,2-dithiol-3-thione results in increased expression of G6PDX mRNA

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:152,201,098...152,220,801

G

GABA type A receptor associated protein like 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of GABARAPL2 mRNA

NCBI chr19:56,819,826...56,830,662
Ensembl chr19:39,910,534...39,924,628

G

cyclin G associated kinase

decreases expression

1,2-dithiol-3-thione results in decreased expression of GAK mRNA

NCBI chr14:1,089,853...1,164,098
Ensembl chr14:1,089,866...1,216,398

G

polypeptide N-acetylgalactosaminyltransferase 1

increases expression

1,2-dithiol-3-thione results in increased expression of GALNT1 mRNA

NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245

G

glyceraldehyde-3-phosphate dehydrogenase

increases expression

1,2-dithiol-3-thione results in increased expression of GAPDH mRNA

NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:157,962,343...157,966,235

G

growth arrest specific 5

decreases expression

1,2-dithiol-3-thione results in decreased expression of GAS5 mRNA

NCBI chr13:73,303,611...73,306,932

G

growth arrest specific 6

decreases expression

1,2-dithiol-3-thione results in decreased expression of GAS6 mRNA

NCBI chr16:82,747,676...82,778,090
Ensembl chr16:76,045,426...76,075,904

G

growth arrest specific 7

increases expression

1,2-dithiol-3-thione results in increased expression of GAS7 mRNA

NCBI chr10:52,152,718...52,383,283
Ensembl chr10:52,152,493...52,383,276

G

GATA binding protein 6

affects expression

1,2-dithiol-3-thione affects the expression of GATA6 mRNA

NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,188,121...2,219,532

G

guanylate binding protein 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of GBP2 mRNA

NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571

G

glucagon receptor

decreases expression

1,2-dithiol-3-thione results in decreased expression of GCGR mRNA

NCBI chr10:106,306,803...106,314,970
Ensembl chr10:105,808,473...105,816,640

G

glucokinase regulator

increases expression

1,2-dithiol-3-thione results in increased expression of GCKR mRNA

NCBI chr 6:30,765,071...30,795,627
Ensembl chr 6:25,045,100...25,075,654

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions
increases activity
increases expression

[1,2-dithiol-3-thione results in increased activity of GCLC protein] which results in decreased susceptibility to Acrolein
1,2-dithiol-3-thione results in increased expression of GCLC mRNA
1,2-dithiol-3-thione results in increased expression of GCLC mRNA; 1,2-dithiol-3-thione results in increased expression of GCLC protein
[1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of GCLC mRNA; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of GCLC mRNA]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of GCLC protein]

PMID:12535742 PMID:15946642 PMID:18367636 PMID:19073213 PMID:19408115 More...

NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

affects expression
multiple interactions

1,2-dithiol-3-thione affects the expression of GCLM mRNA
[1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA

PMID:19162173 PMID:22495766

NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535

G

guanine deaminase

increases expression

1,2-dithiol-3-thione results in increased expression of GDA mRNA

NCBI chr 1:228,333,401...228,408,901
Ensembl chr 1:218,906,815...218,982,416

G

glycerophosphodiester phosphodiesterase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of GDE1 mRNA

NCBI chr 1:173,016,984...173,032,396
Ensembl chr 1:172,954,394...173,032,429

G

GDNF family receptor alpha 2

increases expression

1,2-dithiol-3-thione results in increased expression of GFRA2 mRNA

NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714

G

gamma-glutamyl hydrolase

decreases expression

1,2-dithiol-3-thione results in decreased expression of GGH mRNA

NCBI chr 5:38,326,747...38,349,655
Ensembl chr 5:33,529,880...33,552,787

G

growth hormone receptor

decreases expression

1,2-dithiol-3-thione results in decreased expression of GHR mRNA

PMID:15302862 PMID:19162173

NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:52,542,594...52,804,735

G

glyoxalase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of GLO1 mRNA

NCBI chr20:8,665,061...8,683,095
Ensembl chr20:8,662,801...8,681,649

G

glutamate-ammonia ligase

decreases expression

1,2-dithiol-3-thione results in decreased expression of GLUL mRNA

NCBI chr13:68,519,500...68,585,554
Ensembl chr13:66,025,630...66,035,108

G

guanosine monophosphate reductase

increases expression

1,2-dithiol-3-thione results in increased expression of GMPR mRNA

NCBI chr17:19,357,992...19,395,807
Ensembl chr17:19,151,815...19,189,621

G

G protein subunit alpha 12

increases expression

1,2-dithiol-3-thione results in increased expression of GNA12 mRNA

NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255

G

G protein subunit alpha i3

decreases expression

1,2-dithiol-3-thione results in decreased expression of GNAI3 mRNA

NCBI chr 2:198,430,920...198,468,874
Ensembl chr 2:195,742,642...195,780,742

G

G protein subunit alpha o1

increases expression

1,2-dithiol-3-thione results in increased expression of GNAO1 mRNA

NCBI chr19:11,040,788...11,198,437
Ensembl chr19:11,035,956...11,192,493

G

G protein subunit beta 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of GNB1 mRNA

NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124

G

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

decreases expression

1,2-dithiol-3-thione results in decreased expression of GNE mRNA

NCBI chr 5:63,062,953...63,103,320
Ensembl chr 5:58,267,210...58,307,499

G

glycine N-methyltransferase

decreases expression

1,2-dithiol-3-thione results in decreased expression of GNMT mRNA

NCBI chr 9:21,752,235...21,756,368
Ensembl chr 9:14,254,675...14,258,434

G

glutamic-oxaloacetic transaminase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of GOT1 mRNA

NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:242,357,306...242,380,633

G

glycerol-3-phosphate dehydrogenase 1

increases expression

1,2-dithiol-3-thione results in increased expression of GPD1 mRNA

NCBI chr 7:132,722,982...132,730,373
Ensembl chr 7:130,844,138...130,851,529

G

glutamic--pyruvic transaminase

increases expression

1,2-dithiol-3-thione results in increased expression of GPT mRNA

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494

G

glutathione peroxidase 2

increases expression

1,2-dithiol-3-thione results in increased expression of GPX2 mRNA

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutamate ionotropic receptor NMDA type subunit 3A

increases expression

1,2-dithiol-3-thione results in increased expression of GRIN3A mRNA

NCBI chr 5:64,006,847...64,206,408
Ensembl chr 5:64,009,980...64,206,085

G

Gse1 coiled-coil protein

increases expression

1,2-dithiol-3-thione results in increased expression of GSE1 mRNA

NCBI chr19:48,274,164...48,629,456
Ensembl chr19:48,274,127...48,629,458

G

G1 to S phase transition 1

increases expression

1,2-dithiol-3-thione results in increased expression of GSPT1 mRNA

NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198

G

glutathione-disulfide reductase

increases expression
multiple interactions
increases activity

1,2-dithiol-3-thione results in increased expression of GSR mRNA
1,2-dithiol-3-thione results in increased expression of GSR mRNA; 1,2-dithiol-3-thione results in increased expression of GSR protein
NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of GSR mRNA]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of GSR protein]
1,2-dithiol-3-thione results in increased activity of GSR protein

PMID:15946642 PMID:18367636 PMID:19162173 PMID:19408115

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661

G

glutathione synthetase

increases expression

1,2-dithiol-3-thione results in increased expression of GSS mRNA

NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:144,047,850...144,078,198

G

glutathione S-transferase alpha 2

increases expression

1,2-dithiol-3-thione results in increased expression of GSTA2 mRNA

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 3

increases expression

1,2-dithiol-3-thione results in increased expression of GSTA3 mRNA

NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240

G

glutathione S-transferase alpha 5

increases expression

1,2-dithiol-3-thione results in increased expression of GSTA5 mRNA

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

glutathione S-transferase kappa 1

increases expression

1,2-dithiol-3-thione results in increased expression of GSTK1 mRNA

NCBI chr 4:72,085,532...72,089,934
Ensembl chr 4:71,118,896...71,123,292

G

glutathione S-transferase mu 1

multiple interactions
increases expression

NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of GSTM1 mRNA]

PMID:18367636 PMID:19162173 PMID:19695238

NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase mu 2

increases expression
multiple interactions

1,2-dithiol-3-thione results in increased expression of GSTM2 mRNA
[1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of GSTM2 mRNA

PMID:19162173 PMID:22495766

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase pi 1

increases expression

1,2-dithiol-3-thione results in increased expression of GSTP1 mRNA

PMID:19162173 PMID:19695238

NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226

G

glutathione S-transferase theta 1

increases expression

1,2-dithiol-3-thione results in increased expression of GSTT1 mRNA

PMID:19162173 PMID:19695238

NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,669...12,873,585

G

glutathione S-transferase theta 2

increases expression

1,2-dithiol-3-thione results in increased expression of GSTT2 mRNA

NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288

G

GTF2I repeat domain containing 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of GTF2IRD1 mRNA

NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040

G

GULP PTB domain containing engulfment adaptor 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of GULP1 mRNA

NCBI chr 9:46,622,699...46,899,005
Ensembl chr 9:46,622,669...46,899,005

G

glycogen synthase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of GYS2 mRNA

NCBI chr 4:177,096,063...177,137,236
Ensembl chr 4:175,365,054...175,406,228

G

H1.0 linker histone

decreases expression

1,2-dithiol-3-thione results in decreased expression of H1F0 mRNA

NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694

G

H2A.Z variant histone 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of H2AZ2 mRNA

NCBI chr14:81,293,304...81,312,209
Ensembl chr14:81,293,299...81,312,144
Ensembl chr 4:81,293,299...81,312,144
Ensembl chr16:81,293,299...81,312,144

G

3-hydroxyanthranilate 3,4-dioxygenase

increases expression

1,2-dithiol-3-thione results in increased expression of HAAO mRNA

NCBI chr 6:16,598,325...16,617,590
Ensembl chr 6:10,845,771...10,864,877

G

2-hydroxyacyl-CoA lyase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of HACL1 mRNA

NCBI chr16:6,831,293...6,869,410
Ensembl chr16:6,824,906...6,863,027

G

hydroxyacyl-CoA dehydrogenase

increases expression

1,2-dithiol-3-thione results in increased expression of HADH mRNA

NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:219,787,927...219,830,353

G

HMG-box transcription factor 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of HBP1 mRNA

NCBI chr 6:54,257,118...54,283,373
Ensembl chr 6:48,529,372...48,555,787

G

histone deacetylase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of HDAC2 mRNA

NCBI chr20:42,101,815...42,126,486
Ensembl chr20:40,548,250...40,571,609

G

hes family bHLH transcription factor 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of HES1 mRNA

NCBI chr11:84,210,632...84,213,045
Ensembl chr11:70,705,764...70,708,192

G

hepatocyte growth factor

increases expression

1,2-dithiol-3-thione results in increased expression of HGF mRNA

NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:18,677,101...18,745,409

G

hypoxia inducible factor 1 subunit alpha

decreases expression

1,2-dithiol-3-thione results in decreased expression of HIF1A mRNA

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261

G

HIG1 hypoxia inducible domain family, member 1A

decreases expression

1,2-dithiol-3-thione results in decreased expression of HIGD1A mRNA

NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443

G

high mobility group box 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of HMGB1 mRNA

NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

G

high mobility group box 2

increases expression

1,2-dithiol-3-thione results in increased expression of HMGB2 mRNA

NCBI chr16:37,721,374...37,723,950
Ensembl chr16:32,710,658...32,713,140
Ensembl chr 1:32,710,658...32,713,140

G

3-hydroxy-3-methylglutaryl-CoA reductase

decreases expression

1,2-dithiol-3-thione results in decreased expression of HMGCR mRNA

NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of HMGCS1 mRNA

NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:51,649,497...51,667,100

G

heme oxygenase 1

increases expression
multiple interactions

1,2-dithiol-3-thione results in increased expression of HMOX1 mRNA
[1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 mRNA

PMID:8612205 PMID:22495766

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079

G

hepatocyte nuclear factor 4, alpha

increases expression

1,2-dithiol-3-thione results in increased expression of HNF4A mRNA

NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:152,186,787...152,248,320

G

heterogeneous nuclear ribonucleoprotein A1

decreases expression

1,2-dithiol-3-thione results in decreased expression of HNRNPA1 mRNA

NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609

G

heterogeneous nuclear ribonucleoprotein F

decreases expression

1,2-dithiol-3-thione results in decreased expression of HNRNPF mRNA

NCBI chr 4:151,083,262...151,104,464
Ensembl chr 4:151,083,062...151,109,038

G

heterogeneous nuclear ribonucleoprotein K

decreases expression

1,2-dithiol-3-thione results in decreased expression of HNRNPK mRNA

NCBI chr17:6,269,302...6,280,429
Ensembl chr17:6,262,998...6,274,997

G

homer scaffold protein 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of HOMER1 mRNA

NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785

G

hook microtubule-tethering protein 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of HOOK1 mRNA

NCBI chr 5:110,824,501...110,887,791
Ensembl chr 5:110,824,501...110,887,787

G

4-hydroxyphenylpyruvate dioxygenase

decreases expression

1,2-dithiol-3-thione results in decreased expression of HPD mRNA

NCBI chr12:39,042,246...39,053,596
Ensembl chr12:33,381,231...33,392,766

G

hepsin

decreases expression

1,2-dithiol-3-thione results in decreased expression of HPN mRNA

NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811

G

hypoxanthine phosphoribosyltransferase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of HPRT1 mRNA

NCBI chr X:137,655,744...137,687,718
Ensembl chr X:132,736,096...132,768,154

G

harakiri, BCL2 interacting protein

increases expression

1,2-dithiol-3-thione results in increased expression of HRK mRNA

NCBI chr12:38,387,484...38,409,652

G

hydroxysteroid (17-beta) dehydrogenase 12

decreases expression

1,2-dithiol-3-thione results in decreased expression of HSD17B12 mRNA

NCBI chr 3:79,990,048...80,113,556
Ensembl chr 3:79,990,056...80,113,617

G

hydroxysteroid (17-beta) dehydrogenase 6

increases expression

1,2-dithiol-3-thione results in increased expression of HSD17B6 mRNA

NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of HSD3B2 mRNA

NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033

G

heat shock protein 90 alpha family class A member 1

increases expression

1,2-dithiol-3-thione results in increased expression of HSP90AA1 mRNA

NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:129,702,383...129,707,268

G

heat shock protein 90 alpha family class B member 1

increases expression

1,2-dithiol-3-thione results in increased expression of HSP90AB1 mRNA

PMID:15375163 PMID:19162173

NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:15,433,691...15,438,488

G

heat shock protein 90 beta family member 1

increases expression
decreases expression

1,2-dithiol-3-thione results in increased expression of HSP90B1 mRNA
1,2-dithiol-3-thione results in decreased expression of HSP90B1 mRNA

PMID:15375163 PMID:19162173

NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:21,110,457...21,124,788

G

heat shock protein family A (Hsp70) member 13

decreases expression

1,2-dithiol-3-thione results in decreased expression of HSPA13 mRNA

NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895

G

heat shock protein family A (Hsp70) member 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of HSPA4 mRNA

NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,408,025...37,449,001

G

heat shock protein family A (Hsp70) member 5

increases expression
decreases expression

1,2-dithiol-3-thione results in increased expression of HSPA5 mRNA
1,2-dithiol-3-thione results in decreased expression of HSPA5 mRNA

PMID:15302862 PMID:19162173

NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family A (Hsp70) member 9

decreases expression

1,2-dithiol-3-thione results in decreased expression of HSPA9 mRNA

NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,535,798...26,554,292

G

heat shock protein family D (Hsp60) member 1

affects expression

1,2-dithiol-3-thione affects the expression of HSPD1 mRNA

NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:56,579,201...56,589,662

G

5-hydroxytryptamine receptor 2A

increases expression

1,2-dithiol-3-thione results in increased expression of HTR2A mRNA

NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928

G

5-hydroxytryptamine receptor 4

increases expression

1,2-dithiol-3-thione results in increased expression of HTR4 mRNA

NCBI chr18:55,765,981...55,949,921
Ensembl chr18:55,766,725...55,949,321

G

inhibitor of DNA binding 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of ID3 mRNA

NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:148,372,762...148,374,349

G

isocitrate dehydrogenase (NADP(+)) 2

increases expression

1,2-dithiol-3-thione results in increased expression of IDH2 mRNA

NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025

G

isopentenyl-diphosphate delta isomerase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of IDI1 mRNA

PMID:15302862 PMID:19162173

NCBI chr17:66,539,761...66,547,524
Ensembl chr17:61,629,594...61,637,357

G

interferon induced transmembrane protein 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of IFITM3 mRNA

NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203

G

interferon gamma receptor 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of IFNGR1 mRNA

NCBI chr 1:16,152,811...16,171,439
Ensembl chr 1:14,333,187...14,351,785

G

insulin-like growth factor 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of IGF1 mRNA

NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor 2 receptor

decreases expression

1,2-dithiol-3-thione results in decreased expression of IGF2R mRNA

NCBI chr 1:50,526,878...50,615,265
Ensembl chr 1:47,979,109...48,067,501

G

insulin-like growth factor binding protein, acid labile subunit

decreases expression

1,2-dithiol-3-thione results in decreased expression of IGFALS mRNA

NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677

G

insulin-like growth factor binding protein 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of IGFBP1 mRNA

NCBI chr14:86,261,277...86,266,344
Ensembl chr14:82,047,415...82,052,482

G

insulin-like growth factor binding protein 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of IGFBP3 mRNA

NCBI chr14:86,270,208...86,277,944
Ensembl chr14:82,056,347...82,064,083

G

gamma-2a immunoglobulin heavy chain

decreases expression

1,2-dithiol-3-thione results in decreased expression of IGG-2A mRNA

G

interleukin 18

decreases expression

1,2-dithiol-3-thione results in decreased expression of IL18 mRNA

NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 alpha

decreases expression

1,2-dithiol-3-thione results in decreased expression of IL1A mRNA

NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

increases expression

1,2-dithiol-3-thione results in increased expression of IL1B mRNA

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2 receptor subunit alpha

increases expression

1,2-dithiol-3-thione results in increased expression of IL2RA mRNA

NCBI chr17:71,759,802...71,808,475
Ensembl chr17:66,849,974...66,898,697

G

interleukin 33

decreases expression

1,2-dithiol-3-thione results in decreased expression of IL33 mRNA

NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:227,721,435...227,736,373

G

interleukin 4

increases expression

1,2-dithiol-3-thione results in increased expression of IL4 mRNA

NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750

G

interleukin 6 receptor

decreases expression

1,2-dithiol-3-thione results in decreased expression of IL6RA mRNA

NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:175,298,686...175,347,536

G

ILK associated serine/threonine phosphatase

decreases expression

1,2-dithiol-3-thione results in decreased expression of ILKAP mRNA

NCBI chr 9:91,966,440...91,988,791
Ensembl chr 9:91,966,441...91,988,892

G

inner membrane mitochondrial protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of IMMT mRNA

NCBI chr 4:105,438,657...105,477,370
Ensembl chr 4:103,880,459...103,919,109

G

inositol polyphosphate-4-phosphatase type I A

decreases expression

1,2-dithiol-3-thione results in decreased expression of INPP4A mRNA

NCBI chr 9:39,528,245...39,650,574
Ensembl chr 9:39,528,674...39,646,581

G

insulin induced gene 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of INSIG1 mRNA

NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:7,315,495...7,323,952

G

importin 7

decreases expression

1,2-dithiol-3-thione results in decreased expression of IPO7 mRNA

NCBI chr 1:164,062,702...164,102,938
Ensembl chr 1:164,062,702...164,102,938

G

integrin subunit beta 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ITGB1 mRNA

NCBI chr19:73,602,277...73,650,271
Ensembl chr19:56,705,171...56,753,195

G

inter-alpha-trypsin inhibitor heavy chain 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of ITIH4 mRNA

NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708

G

inositol 1,4,5-trisphosphate receptor, type 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ITPR1 mRNA

NCBI chr 4:142,743,401...143,066,505
Ensembl chr 4:141,187,418...141,510,491

G

isovaleryl-CoA dehydrogenase

decreases expression

1,2-dithiol-3-thione results in decreased expression of IVD mRNA

NCBI chr 3:126,305,584...126,326,016
Ensembl chr 3:105,851,683...105,872,575

G

involucrin

decreases expression

1,2-dithiol-3-thione results in decreased expression of IVL protein

NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100

G

influenza virus NS1A binding protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of IVNS1ABP mRNA

NCBI chr13:65,977,069...65,996,685
Ensembl chr13:63,427,041...63,446,701

G

jagged canonical Notch ligand 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of JAG2 mRNA

NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818

G

Janus kinase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of JAK2 mRNA

NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189

G

kalirin, RhoGEF kinase

affects expression

1,2-dithiol-3-thione affects the expression of KALRN mRNA

NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610

G

kelch repeat and BTB domain containing 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of KBTBD3 mRNA

NCBI chr 8:1,464,162...1,491,144
Ensembl chr 8:1,473,247...1,487,943

G

potassium channel tetramerization domain containing 13

increases expression

1,2-dithiol-3-thione results in increased expression of KCTD13 mRNA

NCBI chr 1:181,534,534...181,552,843
Ensembl chr 1:181,534,515...181,552,881

G

lysine demethylase 3A

decreases expression

1,2-dithiol-3-thione results in decreased expression of KDM3A mRNA

NCBI chr 4:105,189,208...105,233,526
Ensembl chr 4:103,630,908...103,675,073

G

kinesin family member 13A

decreases expression

1,2-dithiol-3-thione results in decreased expression of KIF13A mRNA

NCBI chr17:17,766,597...17,948,517
Ensembl chr17:17,766,597...17,943,615

G

KLF transcription factor 10

decreases expression

1,2-dithiol-3-thione results in decreased expression of KLF10 mRNA

NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994

G

KLF transcription factor 9

decreases expression

1,2-dithiol-3-thione results in decreased expression of KLF9 mRNA

NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037

G

kallikrein B1

decreases expression

1,2-dithiol-3-thione results in decreased expression of KLKB1 mRNA

NCBI chr16:53,690,180...53,714,570
Ensembl chr16:46,958,707...46,982,053

G

killer cell lectin like receptor D1

decreases expression

1,2-dithiol-3-thione results in decreased expression of KLRD1 mRNA

NCBI chr 4:164,730,833...164,742,539
Ensembl chr 4:163,045,067...163,056,518

G

keratin 16

increases expression

1,2-dithiol-3-thione results in increased expression of KRT16 mRNA

NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799

G

KTI12 chromatin associated

decreases expression

1,2-dithiol-3-thione results in decreased expression of KTI12 mRNA

NCBI chr 5:123,601,059...123,602,581
Ensembl chr 5:123,599,436...123,613,964

G

kynurenine aminotransferase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of KYAT1 mRNA

NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355

G

laminin subunit alpha 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of LAMA3 mRNA

NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353

G

lysosomal-associated membrane protein 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of LAMP2 mRNA

NCBI chr X:122,038,734...122,087,745
Ensembl chr X:117,057,606...117,260,522

G

LEM domain nuclear envelope protein 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of LEMD2 mRNA

NCBI chr20:5,282,397...5,296,621
Ensembl chr20:5,282,397...5,296,626

G

galectin 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of LGALS3 mRNA

NCBI chr15:23,099,795...23,111,731
Ensembl chr15:20,607,692...20,632,025

G

leucine-rich repeat-containing G protein-coupled receptor 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of LGR4 mRNA

NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899

G

LIM homeobox 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of LHX2 mRNA

NCBI chr 3:42,523,345...42,553,646
Ensembl chr 3:22,126,007...22,143,908

G

LIF, interleukin 6 family cytokine

increases expression

1,2-dithiol-3-thione results in increased expression of LIF mRNA

NCBI chr14:83,354,602...83,364,053
Ensembl chr14:79,134,574...79,140,482

G

LIF receptor subunit alpha

decreases expression

1,2-dithiol-3-thione results in decreased expression of LIFR mRNA

NCBI chr 2:57,951,787...58,020,357
Ensembl chr 2:56,250,120...56,286,699

G

lipase A, lysosomal acid type

decreases expression

1,2-dithiol-3-thione results in decreased expression of LIPA mRNA

NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:232,024,356...232,057,633

G

lipase C, hepatic type

decreases expression

1,2-dithiol-3-thione results in decreased expression of LIPC mRNA

NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:71,509,635...71,635,464

G

lipopolysaccharide-induced TNF factor

increases expression

1,2-dithiol-3-thione results in increased expression of LITAF mRNA

NCBI chr10:5,163,258...5,199,930
Ensembl chr10:4,625,552...4,692,763

G

lysyl oxidase

increases expression

1,2-dithiol-3-thione results in increased expression of LOX mRNA

NCBI chr18:48,162,889...48,175,640
Ensembl chr18:45,967,343...46,041,477

G

LDL receptor related protein 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of LRP3 mRNA

NCBI chr 1:87,843,815...87,859,147
Ensembl chr 1:87,844,868...87,859,110

G

LDL receptor related protein associated protein 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of LRPAP1 mRNA

NCBI chr14:79,876,002...79,888,011
Ensembl chr14:75,651,376...75,665,414

G

lanosterol synthase

decreases expression

1,2-dithiol-3-thione results in decreased expression of LSS mRNA

NCBI chr20:12,090,641...12,118,230
Ensembl chr20:12,092,774...12,118,762

G

lymphocyte antigen 86

decreases expression

1,2-dithiol-3-thione results in decreased expression of LY86 mRNA

NCBI chr17:27,415,807...27,499,695
Ensembl chr17:27,415,830...27,487,260

G

lysophospholipase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of LYPLA1 mRNA

NCBI chr 5:19,477,408...19,506,568
Ensembl chr 5:14,679,606...14,708,746

G

lymphatic vessel endothelial hyaluronan receptor 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of LYVE1 mRNA

NCBI chr 1:164,962,872...164,976,309
Ensembl chr 1:164,962,872...164,976,309

G

macroH2A.1 histone

increases expression

1,2-dithiol-3-thione results in increased expression of MACROH2A1 mRNA

NCBI chr17:8,484,340...8,547,268
Ensembl chr17:8,479,372...8,542,072

G

MAF bZIP transcription factor B

decreases expression

1,2-dithiol-3-thione results in decreased expression of MAFB mRNA

NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031

G

myelin-associated glycoprotein

increases expression

1,2-dithiol-3-thione results in increased expression of MAG mRNA

NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656

G

magnesium transporter 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of MAGT1 mRNA

NCBI chr X:71,038,489...71,079,704
Ensembl chr X:71,038,489...71,079,699

G

MAM domain containing 4

increases expression

1,2-dithiol-3-thione results in increased expression of MAMDC4 mRNA

NCBI chr 3:8,382,387...8,391,003
Ensembl chr 3:8,382,387...8,391,003

G

mannosidase, alpha, class 1A, member 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of MAN1A mRNA

NCBI chr20:33,202,509...33,385,747
Ensembl chr20:33,202,517...33,385,824

G

mannosidase, alpha, class 2A, member 1

increases expression

1,2-dithiol-3-thione results in increased expression of MAN2A1 mRNA

NCBI chr 9:104,252,001...104,408,349
Ensembl chr 9:104,252,001...104,408,349

G

microtubule-associated protein 1B

increases expression

1,2-dithiol-3-thione results in increased expression of MAP1B mRNA

NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317

G

microtubule-associated protein 1 light chain 3 beta

decreases expression

1,2-dithiol-3-thione results in decreased expression of MAP1LC3B mRNA

NCBI chr19:66,571,631...66,582,270
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690

G

mitogen activated protein kinase kinase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of MAP2K1 mRNA

NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147

G

mitogen activated protein kinase kinase kinase 12

increases expression

1,2-dithiol-3-thione results in increased expression of MAP3K12 mRNA

NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789

G

mitogen activated protein kinase 14

increases expression

1,2-dithiol-3-thione results in increased expression of MAPK14 mRNA

NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,749,670...6,810,589

G

mitogen-activated protein kinase 6

decreases expression

1,2-dithiol-3-thione results in decreased expression of MAPK6 mRNA

NCBI chr 8:76,146,650...76,169,767
Ensembl chr 8:76,146,690...76,169,720

G

myristoylated alanine rich protein kinase C substrate

increases expression

1,2-dithiol-3-thione results in increased expression of MARCKS mRNA

NCBI chr20:42,240,185...42,245,882
Ensembl chr20:40,685,315...40,691,012

G

microtubule affinity regulating kinase 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of MARK3 mRNA

NCBI chr 6:130,626,612...130,716,245
Ensembl chr 6:130,627,482...130,716,647

G

methionine adenosyltransferase 2A

decreases expression

1,2-dithiol-3-thione results in decreased expression of MAT2A mRNA

NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:104,488,466...104,495,493

G

matrin 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of MATR3 mRNA

NCBI chr18:27,154,098...27,193,212
Ensembl chr18:27,163,714...27,193,166

G

mannose binding lectin 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of MBL1 mRNA

NCBI chr16:17,063,232...17,069,271
Ensembl chr16:17,029,118...17,035,174

G

mannose binding lectin 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of MBL2 mRNA

NCBI chr 1:237,429,873...237,465,567

G

membrane bound O-acyltransferase domain containing 7

decreases expression

1,2-dithiol-3-thione results in decreased expression of MBOAT7 mRNA

NCBI chr 1:65,525,206...65,539,538
Ensembl chr 1:65,525,213...65,539,538

G

minichromosome maintenance complex component 6

increases expression

1,2-dithiol-3-thione results in increased expression of MCM6 mRNA

NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960

G

MyoD family inhibitor domain containing

decreases expression

1,2-dithiol-3-thione results in decreased expression of MDFIC mRNA

NCBI chr 4:43,972,310...44,052,162
Ensembl chr 4:43,972,507...44,052,161

G

malate dehydrogenase 1

increases expression

1,2-dithiol-3-thione results in increased expression of MDH1 mRNA

NCBI chr14:99,831,934...99,847,227
Ensembl chr14:95,630,306...95,645,925

G

malic enzyme 1

increases expression

1,2-dithiol-3-thione results in increased expression of ME1 mRNA

NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:87,549,043...87,660,304

G

mediator complex subunit 13L

decreases expression

1,2-dithiol-3-thione results in decreased expression of MED13L mRNA

NCBI chr12:37,807,596...38,004,886
Ensembl chr12:37,808,285...38,004,473

G

mediator complex subunit 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of MED4 mRNA

NCBI chr15:55,106,079...55,116,354
Ensembl chr15:48,696,511...48,706,820

G

methionyl aminopeptidase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of METAP2 mRNA

NCBI chr 7:28,412,429...28,440,458
Ensembl chr 7:28,411,608...28,440,434

G

major facilitator superfamily domain containing 14A

decreases expression

1,2-dithiol-3-thione results in decreased expression of MFSD14A mRNA

NCBI chr 2:204,579,174...204,611,600
Ensembl chr 2:204,579,174...204,659,319

G

alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

decreases expression

1,2-dithiol-3-thione results in decreased expression of MGAT2 mRNA

NCBI chr 6:87,656,360...87,658,849
Ensembl chr 6:87,656,349...87,658,177

G

O-6-methylguanine-DNA methyltransferase

increases expression

1,2-dithiol-3-thione results in increased expression of MGMT mRNA

NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:191,710,930...191,937,756

G

matrix Gla protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of MGP mRNA

NCBI chr 4:171,497,472...171,500,888
Ensembl chr 4:169,766,279...169,769,667

G

microsomal glutathione S-transferase 2

increases expression

1,2-dithiol-3-thione results in increased expression of MGST2 mRNA

NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828

G

macrophage migration inhibitory factor

increases expression

1,2-dithiol-3-thione results in increased expression of MIF mRNA

NCBI chr20:12,767,138...12,791,222
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504

G

MTOR associated protein, LST8 homolog

increases expression

1,2-dithiol-3-thione results in increased expression of MLST8 mRNA

NCBI chr10:14,002,927...14,008,678
Ensembl chr10:13,498,388...13,504,128

G

MMS19 homolog, cytosolic iron-sulfur assembly component

decreases expression

1,2-dithiol-3-thione results in decreased expression of MMS19 mRNA

NCBI chr 1:240,757,279...240,794,291
Ensembl chr 1:240,757,282...240,794,288

G

M-phase phosphoprotein 8

decreases expression

1,2-dithiol-3-thione results in decreased expression of MPHOSPH8 mRNA

NCBI chr15:30,800,546...30,828,415
Ensembl chr15:30,686,613...30,828,810

G

mercaptopyruvate sulfurtransferase

increases expression

1,2-dithiol-3-thione results in increased expression of MPST mRNA

NCBI chr 7:111,836,079...111,843,651
Ensembl chr 7:109,955,675...109,963,141

G

mitochondrial ribosomal protein L38

increases expression

1,2-dithiol-3-thione results in increased expression of MRPL38 mRNA

NCBI chr10:101,365,353...101,372,159
Ensembl chr10:101,365,353...101,372,171

G

methylsterol monooxygenase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of MSMO1 mRNA

NCBI chr16:29,747,113...29,764,360
Ensembl chr16:24,980,697...24,998,016

G

mitochondrially encoded cytochrome c oxidase I

increases expression

1,2-dithiol-3-thione results in increased expression of COX1 mRNA

NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867

G

metallothionein 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of MT1A mRNA

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr X:10,826,032...10,827,049

G

metallothionein 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of MT2A mRNA

NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,832,002...10,832,784

G

mitochondrial carrier 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of MTCH2 mRNA

NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189

G

mitochondrial fission regulator 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of MTFR1 mRNA

NCBI chr 2:101,678,331...101,713,547
Ensembl chr 2:101,679,265...101,713,544

G

murinoglobulin 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of PZP mRNA

NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475

G

Max dimerization protein 3

increases expression

1,2-dithiol-3-thione results in increased expression of MXD3 mRNA

NCBI chr17:9,301,430...9,305,156
Ensembl chr17:9,301,399...9,305,157

G

MAX interactor 1, dimerization protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of MXI1 mRNA

NCBI chr 1:262,329,274...262,389,037
Ensembl chr 1:252,323,303...252,383,681

G

myeloid-associated differentiation marker

decreases expression

1,2-dithiol-3-thione results in decreased expression of MYADM mRNA

NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035

G

myosin light chain 12B

decreases expression

1,2-dithiol-3-thione results in decreased expression of MYL12B mRNA

NCBI chr 9:110,873,855...110,888,187

G

myosin light chain 6B

decreases expression

1,2-dithiol-3-thione results in decreased expression of MYL6B mRNA

NCBI chr X:40,572,012...40,572,991

G

myosin light chain 7

increases expression

1,2-dithiol-3-thione results in increased expression of MYL7 mRNA

NCBI chr14:80,780,684...80,783,259
Ensembl chr14:80,779,776...80,783,244

G

myosin light chain 9

decreases expression

1,2-dithiol-3-thione results in decreased expression of MYL9 mRNA

NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:145,281,937...145,288,333

G

myosin Ib

decreases expression

1,2-dithiol-3-thione results in decreased expression of MYO1B mRNA

NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798

G

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

decreases expression

1,2-dithiol-3-thione results in decreased expression of NAA15 mRNA

NCBI chr 2:135,458,018...135,520,756
Ensembl chr 2:135,457,948...135,520,756

G

N(alpha)-acetyltransferase 20, NatB catalytic subunit

decreases expression

1,2-dithiol-3-thione results in decreased expression of NAA20 mRNA

NCBI chr 3:133,322,036...133,336,843
Ensembl chr 3:133,322,064...133,337,009

G

NEDD8 activating enzyme E1 subunit 1

increases expression

1,2-dithiol-3-thione results in increased expression of NAE1 mRNA

NCBI chr19:452,462...478,591
Ensembl chr19:446,000...472,371

G

nucleosome assembly protein 1-like 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of NAP1L1 mRNA

NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593

G

N-acetyltransferase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of NAT1 mRNA

NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520

G

N-acetyltransferase 8 (GCN5-related) family member 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of NAT8F1 mRNA

NCBI chr 4:118,336,208...118,342,923
Ensembl chr 4:118,332,862...118,344,035

G

nuclear receptor coactivator 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of NCOA4 mRNA

NCBI chr16:7,395,502...7,415,846
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641

G

NADH:ubiquinone oxidoreductase subunit A6

increases expression

1,2-dithiol-3-thione results in increased expression of NDUFA6 mRNA

NCBI chr 7:115,746,460...115,750,317
Ensembl chr 7:113,866,382...113,870,239

G

NADH:ubiquinone oxidoreductase subunit AB1

increases expression

1,2-dithiol-3-thione results in increased expression of NDUFAB1 mRNA

NCBI chr 1:186,075,933...186,091,843
Ensembl chr 1:176,644,703...176,658,099

G

NADH:ubiquinone oxidoreductase subunit B8

increases expression

1,2-dithiol-3-thione results in increased expression of NDUFB8 mRNA

NCBI chr 1:253,357,878...253,362,936
Ensembl chr 1:243,408,619...243,413,817

G

NEDD4 E3 ubiquitin protein ligase

increases expression

1,2-dithiol-3-thione results in increased expression of NEDD4 mRNA

NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951

G

NIMA-related kinase 9

decreases expression

1,2-dithiol-3-thione results in decreased expression of NEK9 mRNA

NCBI chr 6:104,944,056...104,984,538
Ensembl chr 6:104,944,056...104,984,538

G

neuraminidase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of NEU2 mRNA

NCBI chr 9:95,666,338...95,715,209
Ensembl chr 9:88,249,135...88,267,355

G

neurogenin 3

increases expression

1,2-dithiol-3-thione results in increased expression of NEUROG3 mRNA

NCBI chr20:30,622,533...30,624,015
Ensembl chr20:30,079,780...30,081,262

G

NFE2 like bZIP transcription factor 2

decreases expression
multiple interactions
increases activity

1,2-dithiol-3-thione results in decreased expression of NFE2L2 mRNA
1,2-dithiol-3-thione promotes the reaction [NFE2L2 results in decreased susceptibility to Acrolein]; 1,2-dithiol-3-thione promotes the reaction [NFE2L2 results in decreased susceptibility to Cadmium Chloride]; 1,2-dithiol-3-thione promotes the reaction [NFE2L2 results in decreased susceptibility to Hydrogen Peroxide]; 1,2-dithiol-3-thione promotes the reaction [NFE2L2 results in decreased susceptibility to linsidomine]; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] inhibits the reaction [Hydrogen Peroxide results in increased oxidation of TXN1 protein]; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] inhibits the reaction [Hydrogen Peroxide results in increased oxidation of TXN2 protein]; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in decreased susceptibility to Hydrogen Peroxide; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of GCLC mRNA; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of GSTM2 mRNA; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of HMOX1 mRNA; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of PRDX1 mRNA; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of PRDX3 mRNA; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of TXN1 mRNA; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of TXN2 mRNA; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of TXNRD1 mRNA; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of TXNRD2 mRNA; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased activity of CAT protein]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased activity of NQO1 protein]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of CAT mRNA]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of CAT protein]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of GCLC mRNA]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of GCLC protein]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of GSR mRNA]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of GSR protein]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of GSTA1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of GSTM1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of NQO1 protein]

PMID:18367636 PMID:19162173 PMID:22495766

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737

G

nuclear factor I/A

decreases expression

1,2-dithiol-3-thione results in decreased expression of NFIA mRNA

NCBI chr 5:112,436,655...112,781,878
Ensembl chr 5:112,436,644...112,775,885

G

nuclear factor I/B

decreases expression

1,2-dithiol-3-thione results in decreased expression of NFIB mRNA

NCBI chr 5:96,759,208...96,974,001
Ensembl chr 5:96,764,653...96,975,479

G

NFKB inhibitor alpha

decreases expression

1,2-dithiol-3-thione results in decreased expression of NFKBIA mRNA

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941

G

nuclear transcription factor Y subunit beta

decreases expression

1,2-dithiol-3-thione results in decreased expression of NFYB mRNA

NCBI chr 7:22,852,543...22,868,116
Ensembl chr 7:20,964,993...20,980,565

G

nerve growth factor receptor

increases expression

1,2-dithiol-3-thione results in increased expression of NGFR mRNA

NCBI chr10:81,012,077...81,030,305
Ensembl chr10:80,515,299...80,533,518

G

notch receptor 3

increases expression

1,2-dithiol-3-thione results in increased expression of NOTCH3 mRNA

NCBI chr 7:11,783,550...11,834,585
Ensembl chr 7:11,133,706...11,184,025

G

NADPH oxidase 4

increases expression
decreases expression

1,2-dithiol-3-thione results in increased expression of NOX4 mRNA
1,2-dithiol-3-thione results in decreased expression of NOX4 mRNA

PMID:19162173 PMID:19695238

NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:140,901,097...141,077,406

G

natriuretic peptide A

increases expression

1,2-dithiol-3-thione results in increased expression of NPPA mRNA

NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:158,429,042...158,430,351

G

NAD(P)H quinone dehydrogenase 1

increases expression
increases activity
multiple interactions

1,2-dithiol-3-thione results in increased expression of NQO1 mRNA
1,2-dithiol-3-thione results in increased activity of NQO1 protein
1,2-dithiol-3-thione results in increased expression of NQO1 mRNA; 1,2-dithiol-3-thione results in increased expression of NQO1 protein
[1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased activity of NQO1 protein]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of NQO1 protein]
1,2-dithiol-3-thione results in increased expression of and results in increased activity of NQO1 protein

PMID:18367636 PMID:19162173 PMID:19408115 PMID:19695238 PMID:19785463 More...

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 0, group B, member 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of NR0B2 mRNA

NCBI chr 5:151,063,160...151,066,475
Ensembl chr 5:145,779,294...145,782,609

G

nuclear receptor subfamily 1, group D, member 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of NR1D2 mRNA

NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553

G

nuclear receptor subfamily 2, group F, member 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of NR2F1 mRNA

NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123

G

neuropilin 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of NRP1 mRNA

NCBI chr19:73,256,557...73,411,705
Ensembl chr19:56,359,455...56,513,633

G

NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL

decreases expression

1,2-dithiol-3-thione results in decreased expression of NSDHL mRNA

NCBI chr X:155,817,301...155,848,224
Ensembl chr X:150,775,080...150,807,142

G

N-terminal asparagine amidase

decreases expression

1,2-dithiol-3-thione results in decreased expression of NTAN1 mRNA

NCBI chr10:2,111,090...2,126,119

G

nudix hydrolase 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of NUDT4 mRNA

NCBI chr 7:30,188,100...30,204,615
Ensembl chr 7:30,188,100...30,204,615

G

nucleoporin 58

decreases expression

1,2-dithiol-3-thione results in decreased expression of NUP58 mRNA

NCBI chr15:34,358,170...34,407,160
Ensembl chr15:34,358,277...34,407,060

G

nuclear transport factor 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of NUTF2 mRNA

NCBI chr19:50,662,168...50,683,457
Ensembl chr19:33,752,291...33,773,591

G

nuclear RNA export factor 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of NXF1 mRNA

NCBI chr 1:215,084,563...215,097,756
Ensembl chr 1:205,655,375...205,668,636

G

ornithine aminotransferase

decreases expression

1,2-dithiol-3-thione results in decreased expression of OAT mRNA

NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:187,347,865...187,367,682

G

alpha-2u globulin PGCL4

decreases expression

1,2-dithiol-3-thione results in decreased expression of OBP3 mRNA

NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757

G

ornithine decarboxylase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ODC1 mRNA

NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440

G

osteomodulin

decreases expression

1,2-dithiol-3-thione results in decreased expression of OMD mRNA

NCBI chr17:15,060,217...15,068,441
Ensembl chr17:15,060,217...15,068,441

G

olfactory receptor family 10 subfamily AL member 4B

increases expression

1,2-dithiol-3-thione results in increased expression of OR10AL4B mRNA

NCBI chr20:779,579...780,544

G

orosomucoid 1

increases expression

1,2-dithiol-3-thione results in increased expression of ORM1 mRNA

NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154

G

oxidation resistance 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of OXR1 mRNA

NCBI chr 7:72,528,750...72,965,666
Ensembl chr 7:72,528,786...72,965,666

G

prolyl 3-hydroxylase family member 4

increases expression

1,2-dithiol-3-thione results in increased expression of P3H4 mRNA

NCBI chr10:85,338,158...85,345,108
Ensembl chr10:85,338,161...85,345,093

G

prolyl 4-hydroxylase subunit alpha 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of P4HA1 mRNA

NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786

G

platelet-activating factor acetylhydrolase 1b, regulatory subunit 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of PAFAH1B1 mRNA

NCBI chr10:60,031,441...60,090,259
Ensembl chr10:59,534,117...59,591,808

G

poly(A) binding protein interacting protein 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of PAIP1 mRNA

NCBI chr 2:51,523,190...51,550,241
Ensembl chr 2:51,522,921...51,550,241

G

peptidylglycine alpha-amidating monooxygenase

decreases expression

1,2-dithiol-3-thione results in decreased expression of PAM mRNA

NCBI chr 9:105,445,812...105,719,287
Ensembl chr 9:98,122,916...98,271,965

G

par-3 family cell polarity regulator

decreases expression

1,2-dithiol-3-thione results in decreased expression of PARD3 mRNA

NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778

G

pro-apoptotic WT1 regulator

decreases expression

1,2-dithiol-3-thione results in decreased expression of PAWR mRNA

NCBI chr 7:45,531,480...45,611,492
Ensembl chr 7:43,645,084...43,725,028

G

paired box 6

increases expression

1,2-dithiol-3-thione results in increased expression of PAX6 mRNA

NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:92,135,637...92,157,014

G

pyruvate carboxylase

decreases expression

1,2-dithiol-3-thione results in decreased expression of PCX mRNA

NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:201,804,267...201,898,380

G

pericentriolar material 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of PCM1 mRNA

NCBI chr16:51,008,315...51,105,261
Ensembl chr16:51,008,315...51,105,091

G

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

affects expression

1,2-dithiol-3-thione affects the expression of PCMT1 mRNA

NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201

G

protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of PCMTD2 mRNA

NCBI chr 3:168,960,312...168,979,504
Ensembl chr 3:168,960,305...168,979,497

G

phosphatidylcholine transfer protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of PCTP mRNA

NCBI chr10:75,305,999...75,351,919
Ensembl chr10:74,808,887...74,849,867

G

phosducin like

decreases expression

1,2-dithiol-3-thione results in decreased expression of PDCL mRNA

NCBI chr 3:21,110,165...21,119,763
Ensembl chr 3:21,110,167...21,119,715
Ensembl chr 3:21,110,167...21,119,715

G

phosphodiesterase 2A

decreases expression

1,2-dithiol-3-thione results in decreased expression of PDE2A mRNA

NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434

G

phosphodiesterase 3B

decreases expression

1,2-dithiol-3-thione results in decreased expression of PDE3B mRNA

NCBI chr 1:168,606,762...168,770,078
Ensembl chr 1:168,607,022...168,769,334

G

phosphodiesterase 4A

increases expression

1,2-dithiol-3-thione results in increased expression of PDE4A mRNA

NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961

G

phosphodiesterase 4B

affects expression

1,2-dithiol-3-thione affects the expression of PDE4B mRNA

NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696

G

phosphodiesterase 6D

decreases expression

1,2-dithiol-3-thione results in decreased expression of PDE6D mRNA

NCBI chr 9:94,640,932...94,685,918
Ensembl chr 9:87,192,983...87,237,969

G

pyruvate dehydrogenase E1 subunit beta

decreases expression

1,2-dithiol-3-thione results in decreased expression of PDHB mRNA

NCBI chr15:19,182,789...19,188,731
Ensembl chr15:16,750,980...16,758,500

G

pyruvate dehydrogenase phosphatase catalytic subunit 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of PDP2 mRNA

NCBI chr19:392,858...400,529
Ensembl chr19:386,406...394,074

G

podoplanin

increases expression

1,2-dithiol-3-thione results in increased expression of PDPN mRNA

NCBI chr 5:160,884,995...160,919,112
Ensembl chr 5:155,601,691...155,635,656

G

PDZ domain containing 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of PDZK1 mRNA

NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514

G

phosphatidylethanolamine binding protein 1

increases expression

1,2-dithiol-3-thione results in increased expression of PEBP1 mRNA

NCBI chr12:44,946,307...44,967,890
Ensembl chr12:39,302,840...39,307,862

G

period circadian regulator 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of PER2 mRNA

NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:92,007,296...92,049,459

G

peroxisomal biogenesis factor 12

decreases expression

1,2-dithiol-3-thione results in decreased expression of PEX12 mRNA

NCBI chr10:68,095,776...68,103,812
Ensembl chr10:68,095,776...68,099,428

G

peroxisomal biogenesis factor 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of PEX2 mRNA

NCBI chr 2:97,957,479...97,973,767
Ensembl chr 2:96,045,958...96,073,404

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of PFKFB1 mRNA

NCBI chr X:22,936,038...22,989,691
Ensembl chr X:19,508,546...19,562,182

G

phosphoglycerate mutase 1

increases expression

1,2-dithiol-3-thione results in increased expression of PGAM1 mRNA

NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:240,723,920...240,738,452

G

phosphoglycerate mutase 2

increases expression

1,2-dithiol-3-thione results in increased expression of PGAM2 mRNA

NCBI chr14:84,895,763...84,897,874
Ensembl chr14:80,681,776...80,683,940

G

prohibitin 1

increases expression

1,2-dithiol-3-thione results in increased expression of PHB1 mRNA

NCBI chr10:81,102,043...81,114,815
Ensembl chr10:80,605,251...80,618,042

G

phosphoglycerate dehydrogenase

increases expression

1,2-dithiol-3-thione results in increased expression of PHGDH mRNA

NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:185,906,966...185,935,944

G

phosphorylase kinase catalytic subunit gamma 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of PHKG2 mRNA

NCBI chr 1:191,614,738...191,627,615
Ensembl chr 1:182,184,650...182,197,124

G

pleckstrin homology-like domain, family B, member 1

increases expression

1,2-dithiol-3-thione results in increased expression of PHLDB1 mRNA

NCBI chr 8:53,900,338...53,948,325
Ensembl chr 8:45,003,538...45,051,522

G

phosphatidylinositol 3-kinase, catalytic subunit type 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of PIK3C3 mRNA

NCBI chr18:22,119,677...22,203,546
Ensembl chr18:21,845,295...21,929,048

G

phosphoinositide-3-kinase regulatory subunit 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of PIK3R1 mRNA

NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:32,882,032...32,963,631

G

prolactin induced protein

increases expression

1,2-dithiol-3-thione results in increased expression of PIP mRNA

NCBI chr 4:70,787,627...70,791,921
Ensembl chr 4:70,787,627...70,791,921

G

pyruvate kinase L/R

increases expression

1,2-dithiol-3-thione results in increased expression of PKLR mRNA

NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:174,543,039...174,551,870

G

phospholipase A2, group IIC

increases expression

1,2-dithiol-3-thione results in increased expression of PLA2G2C mRNA

NCBI chr 5:156,241,142...156,262,368
Ensembl chr 5:150,959,182...150,981,377

G

phospholipase A2, activating protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of PLAA mRNA

NCBI chr 5:114,544,327...114,576,023
Ensembl chr 5:109,428,265...109,460,282

G

phospholipase C beta 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of PLCB1 mRNA

NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:122,060,031...122,772,869

G

perilipin 2

increases expression

1,2-dithiol-3-thione results in increased expression of PLIN2 mRNA

NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319

G

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of PLOD1 mRNA

NCBI chr 5:158,340,674...158,367,581
Ensembl chr 5:158,340,490...158,367,620

G

phospholipid phosphatase 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of PLPP3 mRNA

NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205

G

peptidase, mitochondrial processing subunit beta

decreases expression

1,2-dithiol-3-thione results in decreased expression of PMPCB mRNA

NCBI chr 4:13,297,583...13,310,363
Ensembl chr 4:13,297,559...13,310,367

G

pinin, desmosome associated protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of PNN mRNA

NCBI chr 6:76,758,138...76,766,451
Ensembl chr 6:76,758,117...76,766,889

G

proline-rich nuclear receptor coactivator 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of PNRC1 mRNA

NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:47,647,071...47,650,161

G

DNA polymerase gamma 2, accessory subunit

decreases expression

1,2-dithiol-3-thione results in decreased expression of POLG2 mRNA

NCBI chr10:92,212,303...92,222,849
Ensembl chr10:91,712,586...91,723,008

G

RNA polymerase II subunit A

increases expression

1,2-dithiol-3-thione results in increased expression of POLR2A mRNA

NCBI chr10:54,951,162...54,977,179
Ensembl chr10:54,452,441...54,478,455

G

RNA polymerase III subunit A

decreases expression

1,2-dithiol-3-thione results in decreased expression of POLR3A mRNA

NCBI chr16:49,178...88,178
Ensembl chr16:49,521...88,172

G

paraoxonase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of PON1 mRNA

NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:33,294,722...33,321,360

G

cytochrome p450 oxidoreductase

affects expression

1,2-dithiol-3-thione affects the expression of POR mRNA

NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245

G

phosphoribosyl pyrophosphate amidotransferase

decreases expression

1,2-dithiol-3-thione results in decreased expression of PPAT mRNA

NCBI chr14:31,570,010...31,604,410
Ensembl chr14:31,216,165...31,250,144

G

peptidylprolyl isomerase B

increases expression

1,2-dithiol-3-thione results in increased expression of PPIB mRNA

NCBI chr 8:75,498,966...75,504,823
Ensembl chr 8:66,603,861...66,630,428

G

protein phosphatase, Mg2+/Mn2+ dependent, 1A

decreases expression

1,2-dithiol-3-thione results in decreased expression of PPM1A mRNA

NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697

G

protein phosphatase, Mg2+/Mn2+ dependent, 1B

decreases expression

1,2-dithiol-3-thione results in decreased expression of PPM1B mRNA

NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974

G

protein phosphatase 1 catalytic subunit beta

decreases expression

1,2-dithiol-3-thione results in decreased expression of PPP1CB mRNA

NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824

G

protein phosphatase 2 catalytic subunit alpha

decreases expression

1,2-dithiol-3-thione results in decreased expression of PPP2CA mRNA

NCBI chr10:36,856,534...36,878,789
Ensembl chr10:36,358,101...36,377,862

G

protein phosphatase 2, regulatory subunit B, alpha

decreases expression

1,2-dithiol-3-thione results in decreased expression of PPP2R2A mRNA

NCBI chr15:45,380,142...45,439,428
Ensembl chr15:41,204,200...41,263,924

G

protein phosphatase 3 catalytic subunit alpha

decreases expression

1,2-dithiol-3-thione results in decreased expression of PPP3CA mRNA

NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:225,165,766...225,438,974

G

protein phosphatase 6, catalytic subunit

decreases expression

1,2-dithiol-3-thione results in decreased expression of PPP6C mRNA

NCBI chr 3:22,929,816...22,962,123
Ensembl chr 3:22,931,577...22,962,113

G

palmitoyl-protein thioesterase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of PPT1 mRNA

NCBI chr 5:135,121,164...135,142,048
Ensembl chr 5:135,121,163...135,142,048

G

peroxiredoxin 1

multiple interactions

[1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of PRDX1 mRNA

NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856

G

peroxiredoxin 3

multiple interactions

[1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of PRDX3 mRNA

NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111

G

DNA primase subunit 1

increases expression

1,2-dithiol-3-thione results in increased expression of PRIM1 mRNA

NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526

G

protein kinase cAMP-activated catalytic subunit beta

decreases expression

1,2-dithiol-3-thione results in decreased expression of PRKACB mRNA

NCBI chr 2:238,297,140...238,389,317
Ensembl chr 2:235,636,885...235,726,198

G

protein kinase cAMP-dependent type II regulatory subunit alpha

increases expression

1,2-dithiol-3-thione results in increased expression of PRKAR2A mRNA

NCBI chr 8:118,271,608...118,337,332
Ensembl chr 8:109,395,833...109,455,628

G

protein kinase C, alpha

increases expression

1,2-dithiol-3-thione results in increased expression of PRKCA mRNA

NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012

G

protein kinase C, beta

decreases expression

1,2-dithiol-3-thione results in decreased expression of PRKCB mRNA

NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:176,832,226...177,163,536

G

protein kinase C, gamma

increases expression

1,2-dithiol-3-thione results in increased expression of PRKCG mRNA

NCBI chr 1:74,748,272...74,777,611
Ensembl chr 1:65,832,855...65,859,384

G

protein kinase C, eta

decreases expression

1,2-dithiol-3-thione results in decreased expression of PRKCH mRNA

NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654

G

phosphoribosyl pyrophosphate synthetase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of PRPS1 mRNA

NCBI chr X:104,132,139...104,154,191
Ensembl chr X:104,132,141...104,154,187

G

proteasome 20S subunit alpha 1

increases expression

1,2-dithiol-3-thione results in increased expression of PSMA1 mRNA

NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472

G

proteasome 20S subunit alpha 2

increases expression
decreases expression

1,2-dithiol-3-thione results in increased expression of PSMA2 mRNA
1,2-dithiol-3-thione results in decreased expression of PSMA2 mRNA

PMID:15375163 PMID:19162173

NCBI chr17:50,554,536...50,564,923
Ensembl chr17:50,551,924...50,564,938

G

proteasome 20S subunit alpha 4

increases expression

1,2-dithiol-3-thione results in increased expression of PSMA4 mRNA

NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890

G

proteasome 20S subunit alpha 5

increases expression

1,2-dithiol-3-thione results in increased expression of PSMA5 mRNA

NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731

G

proteasome 20S subunit alpha 6

increases expression

1,2-dithiol-3-thione results in increased expression of PSMA6 mRNA

NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554

G

proteasome 20S subunit alpha 7

increases expression

1,2-dithiol-3-thione results in increased expression of PSMA7 mRNA

NCBI chr 3:167,137,279...167,143,626
Ensembl chr 3:167,137,263...167,143,672

G

proteasome 20S subunit beta 1

increases expression

1,2-dithiol-3-thione results in increased expression of PSMB1 mRNA

NCBI chr 1:65,115,770...65,136,516
Ensembl chr 1:56,420,618...56,463,560

G

proteasome 20S subunit beta 2

increases expression

1,2-dithiol-3-thione results in increased expression of PSMB2 mRNA

NCBI chr 5:138,970,564...139,002,715
Ensembl chr 5:138,970,533...139,021,137

G

proteasome 20S subunit beta 3

increases expression

1,2-dithiol-3-thione results in increased expression of PSMB3 mRNA

NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521

G

proteasome 20S subunit beta 4

increases expression

1,2-dithiol-3-thione results in increased expression of PSMB4 mRNA

PMID:15375163 PMID:19162173

NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746

G

proteasome 20S subunit beta 5

increases expression
increases activity

1,2-dithiol-3-thione results in increased expression of PSMB5 mRNA
1,2-dithiol-3-thione results in increased activity of PSMB5 protein

PMID:15375163 PMID:22959925

NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440

G

proteasome 20S subunit beta 6

increases expression

1,2-dithiol-3-thione results in increased expression of PSMB6 mRNA

PMID:15375163 PMID:22959925

NCBI chr10:55,239,256...55,241,586
Ensembl chr10:55,239,241...55,241,586

G

proteasome 20S subunit beta 7

increases expression

1,2-dithiol-3-thione results in increased expression of PSMB7 mRNA

NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937

G

proteasome 26S subunit, ATPase 1

increases expression

1,2-dithiol-3-thione results in increased expression of PSMC1 mRNA

NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123

G

proteasome 26S subunit, ATPase 2

increases expression

1,2-dithiol-3-thione results in increased expression of PSMC2 mRNA

NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185

G

proteasome 26S subunit, ATPase 6

increases expression

1,2-dithiol-3-thione results in increased expression of PSMC6 mRNA

NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055

G

proteasome 26S subunit, non-ATPase 14

increases expression

1,2-dithiol-3-thione results in increased expression of PSMD14 mRNA

NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076

G

proteasome 26S subunit, non-ATPase 5

increases expression

1,2-dithiol-3-thione results in increased expression of PSMD5 mRNA

NCBI chr 3:18,133,715...18,151,000
Ensembl chr 3:18,133,717...18,151,029

G

proteasome 26S subunit, non-ATPase 7

increases expression

1,2-dithiol-3-thione results in increased expression of PSMD7 mRNA

NCBI chr19:35,494,317...35,501,605
Ensembl chr19:35,494,316...35,501,588

G

proteasome 26S subunit, non-ATPase 8

increases expression

1,2-dithiol-3-thione results in increased expression of PSMD8 mRNA

NCBI chr 1:84,474,377...84,481,209
Ensembl chr 1:84,474,378...84,481,209

G

proteasome activator subunit 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of PSME4 mRNA

NCBI chr14:104,505,716...104,609,410
Ensembl chr14:104,505,716...104,609,408

G

phosphatase and tensin homolog

decreases expression

1,2-dithiol-3-thione results in decreased expression of PTEN mRNA

NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838

G

prostaglandin reductase 1

multiple interactions
increases expression

1,2-dithiol-3-thione results in increased expression of and results in increased activity of PTGR1 protein
1,2-dithiole-3-thione increases expression of Ptgr1 mRNA in the liver

CTD
RGD

PMID:25179160 PMID:8968041

NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666

G

protein tyrosine kinase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of PTK2 mRNA

NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:105,126,728...105,331,783

G

parathymosin

increases expression

1,2-dithiol-3-thione results in increased expression of PTMS mRNA

NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009

G

PTOV1, extended AT-hook containing adaptor protein

increases expression

1,2-dithiol-3-thione results in increased expression of PTOV1 mRNA

NCBI chr 1:95,347,065...95,354,514
Ensembl chr 1:95,347,068...95,353,613

G

protein tyrosine phosphatase 4A1

decreases expression

1,2-dithiol-3-thione results in decreased expression of PTP4A1 mRNA

NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964

G

protein tyrosine phosphatase, non-receptor type 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of PTPN2 mRNA

NCBI chr18:63,498,890...63,564,571
Ensembl chr18:61,229,014...61,294,627

G

protein tyrosine phosphatase, non-receptor type 23

increases expression

1,2-dithiol-3-thione results in increased expression of PTPN23 mRNA

NCBI chr 8:110,360,804...110,383,271
Ensembl chr 8:110,360,804...110,383,271

G

protein tyrosine phosphatase, non-receptor type 6

decreases expression

1,2-dithiol-3-thione results in decreased expression of PTPN6 mRNA

NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:157,526,035...157,550,984

G

protein tyrosine phosphatase, receptor type, C

decreases expression

1,2-dithiol-3-thione results in decreased expression of PTPRC mRNA

NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692

G

protein tyrosine phosphatase, receptor type, U

increases expression

1,2-dithiol-3-thione results in increased expression of PTPRU mRNA

NCBI chr 5:149,234,624...149,308,857
Ensembl chr 5:143,950,965...144,024,768

G

purine rich element binding protein A

decreases expression

1,2-dithiol-3-thione results in decreased expression of PURA mRNA

NCBI chr18:27,885,071...27,905,509
Ensembl chr18:27,884,556...27,905,513

G

glycogen phosphorylase L

decreases expression

1,2-dithiol-3-thione results in decreased expression of PYGL mRNA

NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:88,697,593...88,740,310

G

glutaminyl-peptide cyclotransferase

increases expression

1,2-dithiol-3-thione results in increased expression of QPCT mRNA

NCBI chr 6:15,964,656...15,996,730
Ensembl chr 6:15,964,657...15,996,711

G

RAB10, member RAS oncogene family

decreases expression

1,2-dithiol-3-thione results in decreased expression of RAB10 mRNA

NCBI chr 6:26,267,081...26,319,739
Ensembl chr 6:26,266,859...26,320,193

G

RAB11a, member RAS oncogene family

decreases expression

1,2-dithiol-3-thione results in decreased expression of RAB11A mRNA

NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525

G

RAB14, member RAS oncogene family

increases expression

1,2-dithiol-3-thione results in increased expression of RAB14 mRNA

NCBI chr 3:18,501,953...18,523,253
Ensembl chr 3:18,501,963...18,523,172

G

RAB1A, member RAS oncogene family

decreases expression

1,2-dithiol-3-thione results in decreased expression of RAB1A mRNA

NCBI chr14:98,623,582...98,648,766
Ensembl chr14:94,415,275...94,448,248

G

RAB27A, member RAS oncogene family

increases expression

1,2-dithiol-3-thione results in increased expression of RAB27A mRNA

NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829

G

RAB28, member RAS oncogene family

decreases expression

1,2-dithiol-3-thione results in decreased expression of RAB28 mRNA

NCBI chr14:69,245,846...69,322,968
Ensembl chr14:69,245,854...69,322,967

G

RAB33B, member RAS oncogene family

decreases expression

1,2-dithiol-3-thione results in decreased expression of RAB33B mRNA

NCBI chr 2:137,678,953...137,689,581
Ensembl chr 2:135,528,116...135,538,719

G

RAB3A interacting protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of RAB3IP mRNA

NCBI chr 7:52,531,461...52,575,295
Ensembl chr 7:52,532,401...52,561,043

G

RAB5A, member RAS oncogene family

decreases expression

1,2-dithiol-3-thione results in decreased expression of RAB5A mRNA

NCBI chr 9:6,720,057...6,749,456
Ensembl chr 9:6,484,469...6,512,873

G

RAB5B, member RAS oncogene family

decreases expression

1,2-dithiol-3-thione results in decreased expression of RAB5B mRNA

NCBI chr 7:1,693,971...1,712,936
Ensembl chr 7:1,109,454...1,128,268

G

RAB6A, member RAS oncogene family

decreases expression

1,2-dithiol-3-thione results in decreased expression of RAB6A mRNA

NCBI chr 1:154,957,870...155,008,922
Ensembl chr 1:154,958,189...154,996,715

G

Rab geranylgeranyltransferase subunit beta

decreases expression

1,2-dithiol-3-thione results in decreased expression of RABGGTB mRNA

NCBI chr 2:242,844,758...242,850,951
Ensembl chr 2:242,844,762...242,851,050

G

receptor for activated C kinase 1

increases expression

1,2-dithiol-3-thione results in increased expression of RACK1 mRNA

NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,169,169...33,174,975

G

ralA binding protein 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of RALBP1 mRNA

NCBI chr 9:112,903,289...112,940,093
Ensembl chr 9:105,456,425...105,492,707

G

RAP1B, member of RAS oncogene family

decreases expression

1,2-dithiol-3-thione results in decreased expression of RAP1B mRNA

NCBI chr 7:55,308,922...55,342,217
Ensembl chr 7:53,423,130...53,456,370

G

Rap guanine nucleotide exchange factor 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of RAPGEF4 mRNA

NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316

G

retinoic acid receptor, beta

decreases expression

1,2-dithiol-3-thione results in decreased expression of RARB mRNA

NCBI chr15:10,837,252...11,482,037
Ensembl chr15:8,406,492...9,051,288

G

RB transcriptional corepressor like 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of RBL2 mRNA

NCBI chr19:32,049,690...32,096,467
Ensembl chr19:15,876,853...15,923,572

G

RNA binding motif protein 25

decreases expression

1,2-dithiol-3-thione results in decreased expression of RBM25 mRNA

NCBI chr 6:103,271,775...103,319,090
Ensembl chr 6:103,271,801...103,317,854

G

RNA binding motif protein 3

increases expression

1,2-dithiol-3-thione results in increased expression of RBM3 mRNA

NCBI chr X:17,020,863...17,024,341
Ensembl chr X:14,348,910...14,353,580

G

RNA binding motif protein 39

decreases expression

1,2-dithiol-3-thione results in decreased expression of RBM39 mRNA

NCBI chr 3:144,662,998...144,696,222
Ensembl chr 3:144,663,001...144,696,213

G

renin binding protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of RENBP mRNA

NCBI chr X:156,812,785...156,821,860
Ensembl chr X:151,661,458...151,670,516

G

REV1, DNA directed polymerase

decreases expression

1,2-dithiol-3-thione results in decreased expression of REV1 mRNA

NCBI chr 9:40,278,100...40,351,764
Ensembl chr 9:40,278,101...40,351,576

G

riboflavin kinase

increases expression

1,2-dithiol-3-thione results in increased expression of RFK mRNA

NCBI chr 1:214,799,880...214,807,440
Ensembl chr 1:214,799,825...214,807,438
Ensembl chr X:214,799,825...214,807,438

G

raftlin family member 2

increases expression

1,2-dithiol-3-thione results in increased expression of RFTN2 mRNA

NCBI chr 9:56,651,617...56,707,830
Ensembl chr 9:56,630,460...56,707,810

G

regucalcin

decreases expression

1,2-dithiol-3-thione results in decreased expression of RGN mRNA

NCBI chr X:4,172,537...4,190,112
Ensembl chr X:1,619,032...1,634,450

G

Ras homolog, mTORC1 binding

decreases expression

1,2-dithiol-3-thione results in decreased expression of RHEB mRNA

NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160

G

ribonuclease A family member 1, pancreatic

increases expression

1,2-dithiol-3-thione results in increased expression of RNASE1 mRNA

NCBI chr15:24,361,924...24,363,633
Ensembl chr15:24,361,927...24,363,624

G

RNA (guanine-7-) methyltransferase

decreases expression

1,2-dithiol-3-thione results in decreased expression of RNMT mRNA

NCBI chr18:61,886,230...61,909,775
Ensembl chr18:61,886,292...61,909,775

G

replication protein A3

decreases expression

1,2-dithiol-3-thione results in decreased expression of RPA3 mRNA

NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709

G

rabphilin 3A-like (without C2 domains)

decreases expression

1,2-dithiol-3-thione results in decreased expression of RPH3AL mRNA

NCBI chr10:60,689,943...60,833,354
Ensembl chr10:60,690,031...60,801,883

G

ribosomal protein L13

increases expression

1,2-dithiol-3-thione results in increased expression of RPL13 mRNA

NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
Ensembl chr 3:51,153,924...51,163,014

G

ribosomal protein L18A

increases expression

1,2-dithiol-3-thione results in increased expression of RPL18A mRNA

NCBI chr16:18,542,555...18,544,578
Ensembl chr16:18,542,566...18,545,546
Ensembl chr 1:18,542,566...18,545,546

G

ribosomal protein L28

increases expression

1,2-dithiol-3-thione results in increased expression of RPL28 mRNA

NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032

G

ribosomal protein L35

increases expression

1,2-dithiol-3-thione results in increased expression of RPL35 mRNA

NCBI chr 3:22,753,255...22,756,217
Ensembl chr 3:22,753,253...22,756,243

G

ribosomal protein L36

increases expression

1,2-dithiol-3-thione results in increased expression of RPL36 mRNA

NCBI chr 9:1,441,986...1,447,397
Ensembl chr 6:98,809,534...98,809,897
Ensembl chr 5:98,809,534...98,809,897

G

ribosomal protein L7A

increases expression

1,2-dithiol-3-thione results in increased expression of RPL7A mRNA

NCBI chr 3:10,239,026...10,241,703
Ensembl chr 3:10,239,001...10,241,716
Ensembl chr18:10,239,001...10,241,716

G

ribosomal protein lateral stalk subunit P0

increases expression

1,2-dithiol-3-thione results in increased expression of RPLP0 mRNA

NCBI chr12:41,054,363...41,057,632
Ensembl chr12:41,054,179...41,057,632

G

ribophorin I

increases expression

1,2-dithiol-3-thione results in increased expression of RPN1 mRNA

NCBI chr 4:122,100,976...122,122,382
Ensembl chr 4:120,543,667...120,565,069

G

ribosomal protein S10

increases expression

1,2-dithiol-3-thione results in increased expression of RPS10 mRNA

NCBI chr20:5,694,313...5,698,922
Ensembl chr20:5,694,313...5,699,044
Ensembl chr 6:5,694,313...5,699,044
Ensembl chr 6:5,694,313...5,699,044

G

ribosomal protein S12

increases expression

1,2-dithiol-3-thione results in increased expression of RPS12 mRNA

NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014

G

ribosomal protein S15

decreases expression

1,2-dithiol-3-thione results in decreased expression of RPS15 mRNA

NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450
Ensembl chr 7:9,416,004...9,417,450

G

ribosomal protein S24

increases expression

1,2-dithiol-3-thione results in increased expression of RPS24 mRNA

NCBI chr16:89,538...94,267
Ensembl chr16:89,604...94,279

G

ribosomal protein S6 kinase B1

decreases expression

1,2-dithiol-3-thione results in decreased expression of RPS6KB1 mRNA

NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,323,777...71,367,908

G

ribosomal protein SA

increases expression

1,2-dithiol-3-thione results in increased expression of RPSA mRNA

NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247

G

Ras-related GTP binding A

decreases expression

1,2-dithiol-3-thione results in decreased expression of RRAGA mRNA

NCBI chr 5:101,113,341...101,114,936
Ensembl chr 5:101,112,859...101,114,510

G

RT1 class II, locus Ba

decreases expression

1,2-dithiol-3-thione results in decreased expression of RT1-BA mRNA

NCBI chr20:4,577,057...4,581,650
Ensembl chr20:4,575,134...4,579,744

G

RT1 class I, locus CE12

decreases expression

1,2-dithiol-3-thione results in decreased expression of RT1-CE12 mRNA

NCBI chr20:3,290,831...3,347,349

G

RT1 class II, locus Da

decreases expression

1,2-dithiol-3-thione results in decreased expression of RT1-DA mRNA

NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,512,911...4,518,455

G

RT1 class II, locus Db1

decreases expression

1,2-dithiol-3-thione results in decreased expression of RT1-DB1 mRNA

NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,548,666...4,558,258

G

RT1 class II, locus DMb

decreases expression

1,2-dithiol-3-thione results in decreased expression of HLA-DMB mRNA

NCBI chr20:4,695,009...4,702,560
Ensembl chr20:4,693,103...4,700,340

G

RT1 class Ib, locus N3

decreases expression

1,2-dithiol-3-thione results in decreased expression of RT1-N3 mRNA

NCBI chr20:2,666,469...2,670,355
Ensembl chr20:2,661,584...2,665,530

G

RT1 class Ib, locus S3

decreases expression

1,2-dithiol-3-thione results in decreased expression of RT1-S3 mRNA

NCBI chr20:2,675,463...2,680,229
Ensembl chr20:2,670,709...2,675,411

G

retinoid X receptor beta

increases expression

1,2-dithiol-3-thione results in increased expression of RXRB mRNA

NCBI chr20:4,818,707...4,824,968
Ensembl chr20:4,816,815...4,828,773

G

S100 calcium binding protein A10

decreases expression
increases expression

1,2-dithiol-3-thione results in decreased expression of S100A10 mRNA
1,2-dithiol-3-thione results in increased expression of S100A10 mRNA

PMID:15302862 PMID:19162173

NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661

G

sarcosine dehydrogenase

increases expression

1,2-dithiol-3-thione results in increased expression of SARDH mRNA

NCBI chr 3:30,908,621...30,973,409
Ensembl chr 3:10,510,553...10,573,874

G

SR-related CTD-associated factor 1

increases expression

1,2-dithiol-3-thione results in increased expression of SCAF1 mRNA

NCBI chr 1:95,485,448...95,499,389
Ensembl chr 1:95,485,448...95,496,029

G

secretory carrier membrane protein 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of SCAMP1 mRNA

NCBI chr 2:25,433,958...25,516,734
Ensembl chr 2:25,433,959...25,516,673

G

stearoyl-Coenzyme A desaturase 2

affects expression

1,2-dithiol-3-thione affects the expression of SCD2 mRNA

NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232

G

selenocysteine lyase

increases expression

1,2-dithiol-3-thione results in increased expression of SCLY mRNA

NCBI chr 9:91,890,269...91,910,947
Ensembl chr 9:91,890,306...91,910,941

G

sodium voltage-gated channel beta subunit 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of SCN2B mRNA

NCBI chr 8:45,425,629...45,437,765
Ensembl chr 8:45,425,629...45,437,765

G

sterol carrier protein 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of SCP2 mRNA

NCBI chr 5:128,035,714...128,110,015
Ensembl chr 5:122,776,549...122,881,287

G

syndecan 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of SDC1 mRNA

NCBI chr 6:37,282,041...37,304,503
Ensembl chr 6:31,562,739...31,585,264

G

syndecan binding protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of SDCBP mRNA

NCBI chr 5:24,245,279...24,314,712
Ensembl chr 5:19,489,961...19,527,572

G

SEC11 homolog A, signal peptidase complex subunit

decreases expression

1,2-dithiol-3-thione results in decreased expression of SEC11A mRNA

NCBI chr 1:134,881,448...134,909,427
Ensembl chr 1:134,875,265...134,915,069

G

Sec23 homolog A, COPII coat complex component

increases expression

1,2-dithiol-3-thione results in increased expression of SEC23A mRNA

NCBI chr 6:82,393,699...82,442,594
Ensembl chr 6:76,658,427...76,706,035

G

SEC31 homolog A, COPII coat complex component

increases expression

1,2-dithiol-3-thione results in increased expression of SEC31A mRNA

NCBI chr14:9,214,324...9,269,281
Ensembl chr14:9,214,349...9,269,273

G

SEC62 homolog, preprotein translocation factor

decreases expression

1,2-dithiol-3-thione results in decreased expression of SEC62 mRNA

NCBI chr 2:112,570,810...112,598,198
Ensembl chr 2:112,570,819...112,601,814

G

selenoprotein P

decreases expression

1,2-dithiol-3-thione results in decreased expression of SELENOP mRNA

NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:52,498,339...52,508,852

G

selenophosphate synthetase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of SEPHS2 mRNA

NCBI chr 1:181,893,146...181,895,464
Ensembl chr 1:181,892,599...181,895,497

G

serine incorporator 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of SERINC3 mRNA

NCBI chr 3:152,301,882...152,321,327
Ensembl chr 3:152,301,772...152,321,808

G

serine incorporator 5

decreases expression

1,2-dithiol-3-thione results in decreased expression of SERINC5 mRNA

NCBI chr 2:23,846,899...23,950,346
Ensembl chr 2:23,846,900...23,950,346

G

stress-associated endoplasmic reticulum protein 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of SERP1 mRNA

NCBI chr 2:142,757,254...142,761,243
Ensembl chr 2:142,757,270...142,761,116

G

serpin family A member 6

decreases expression

1,2-dithiol-3-thione results in decreased expression of SERPINA6 mRNA

NCBI chr 6:122,780,040...122,790,274
Ensembl chr 6:122,780,043...122,790,349

G

serpin family F member 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of SERPINF1 mRNA

NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,249,708...60,262,646

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splicing factor 3b, subunit 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of SF3B1 mRNA

NCBI chr 9:56,492,403...56,532,300
Ensembl chr 9:56,492,403...56,532,300

G

splicing factor proline and glutamine rich

decreases expression

1,2-dithiol-3-thione results in decreased expression of SFPQ mRNA

NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472

G

SH2B adaptor protein 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of SH2B3 mRNA

NCBI chr12:40,391,755...40,414,336
Ensembl chr12:34,731,911...34,753,616

G

SH2 domain containing 4A

decreases expression

1,2-dithiol-3-thione results in decreased expression of SH2D4A mRNA

NCBI chr16:21,339,010...21,409,360
Ensembl chr16:21,340,015...21,409,260

G

SH3 domain containing GRB2 like 3, endophilin A3

decreases expression

1,2-dithiol-3-thione results in decreased expression of SH3GL3 mRNA

NCBI chr 1:136,124,500...136,255,669
Ensembl chr 1:136,124,499...136,255,584

G

SHC adaptor protein 3

increases expression

1,2-dithiol-3-thione results in increased expression of SHC3 mRNA

NCBI chr17:13,803,980...13,924,433
Ensembl chr17:13,651,202...13,772,710

G

sigma non-opioid intracellular receptor 1

increases expression

1,2-dithiol-3-thione results in increased expression of SIGMAR1 mRNA

NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017

G

stem-loop histone mRNA binding protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of SLBP mRNA

NCBI chr14:77,071,441...77,081,911
Ensembl chr14:77,071,632...77,081,906

G

solute carrier family 11 member 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of SLC11A2 mRNA

NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145

G

solute carrier family 22 member 5

decreases expression

1,2-dithiol-3-thione results in decreased expression of SLC22A5 mRNA

NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309

G

solute carrier family 25 member 10

decreases expression

1,2-dithiol-3-thione results in decreased expression of SLC25A10 mRNA

NCBI chr10:106,264,396...106,271,895
Ensembl chr10:105,765,372...105,773,556

G

solute carrier family 25 member 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of SLC25A4 mRNA

NCBI chr16:52,805,521...52,809,316
Ensembl chr16:46,072,939...46,076,733

G

solute carrier family 25, member 51

decreases expression

1,2-dithiol-3-thione results in decreased expression of SLC25A51 mRNA

NCBI chr 5:59,649,980...59,663,454
Ensembl chr 5:59,649,744...59,663,581

G

solute carrier family 2 member 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of SLC2A1 mRNA

NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:132,717,196...132,745,416

G

solute carrier family 2 member 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of SLC2A2 mRNA

NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:111,611,774...111,639,933

G

solute carrier family 2 member 5

decreases expression

1,2-dithiol-3-thione results in decreased expression of SLC2A5 mRNA

NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106

G

solute carrier family 40 member 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of SLC40A1 mRNA

NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481

G

solute carrier family 6 member 13

decreases expression

1,2-dithiol-3-thione results in decreased expression of SLC6A13 mRNA

NCBI chr 4:156,211,381...156,248,491
Ensembl chr 4:154,540,468...154,576,152

G

solute carrier family 8 member A1

decreases expression

1,2-dithiol-3-thione results in decreased expression of SLC8A1 mRNA

NCBI chr 6:18,975,498...19,299,704
Ensembl chr 6:13,194,662...13,535,628

G

slit guidance ligand 1

increases expression

1,2-dithiol-3-thione results in increased expression of SLIT1 mRNA

NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127

G

SMAD family member 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of SMAD2 mRNA

NCBI chr18:72,124,792...72,193,345
Ensembl chr18:69,850,377...69,912,323

G

SMAD family member 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of SMAD4 mRNA

NCBI chr18:69,518,988...69,549,684
Ensembl chr18:67,243,742...67,274,438

G

SWI/SNF related BAF chromatin remodeling complex subunit D2

decreases expression

1,2-dithiol-3-thione results in decreased expression of SMARCD2 mRNA

NCBI chr10:91,193,752...91,202,817
Ensembl chr10:91,193,752...91,204,341

G

synaptosome associated protein 23

decreases expression

1,2-dithiol-3-thione results in decreased expression of SNAP23 mRNA

NCBI chr 3:107,514,088...107,546,177
Ensembl chr 3:107,514,131...107,544,320

G

sorting nexin 4

decreases expression

1,2-dithiol-3-thione results in decreased expression of SNX4 mRNA

NCBI chr11:80,965,965...81,023,234
Ensembl chr11:67,460,870...67,518,174

G

suppressor of cytokine signaling 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of SOCS2 mRNA

NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:30,008,578...30,043,548

G

sorbin and SH3 domain containing 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of SORBS2 mRNA

NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514

G

SOS Ras/Rac guanine nucleotide exchange factor 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of SOS1 mRNA

NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:14,533,360...14,611,107

G

secreted protein acidic and cysteine rich

decreases expression

1,2-dithiol-3-thione results in decreased expression of SPARC mRNA

NCBI chr10:40,017,065...40,038,816
Ensembl chr10:39,516,406...39,538,396

G

serine peptidase inhibitor, Kazal type 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of SPINK1 mRNA

NCBI chr18:36,121,626...36,133,596
Ensembl chr18:35,824,550...35,882,642

G

secreted phosphoprotein 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of SPP2 mRNA

NCBI chr 9:96,454,636...96,474,453
Ensembl chr 9:89,007,175...89,026,688

G

spectrin, alpha, non-erythrocytic 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of SPTAN1 mRNA

NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046

G

squalene epoxidase

decreases expression

1,2-dithiol-3-thione results in decreased expression of SQLE mRNA

NCBI chr 7:92,758,175...92,773,049
Ensembl chr 7:90,868,011...90,883,618

G

sequestosome 1

increases expression

1,2-dithiol-3-thione results in increased expression of SQSTM1 mRNA

NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673

G

steroid 5 alpha-reductase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of SRD5A1 mRNA

NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:33,686,391...33,720,461

G

steroid 5 alpha-reductase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of SRD5A2 mRNA

NCBI chr 6:27,178,089...27,217,588
Ensembl chr 6:21,426,215...21,462,112

G

sterol regulatory element binding transcription factor 1

increases expression

1,2-dithiol-3-thione results in increased expression of SREBF1 mRNA

NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650

G

serine and arginine rich splicing factor 5

decreases expression

1,2-dithiol-3-thione results in decreased expression of SRSF5 mRNA

NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177

G

SS18 subunit of BAF chromatin remodeling complex

decreases expression

1,2-dithiol-3-thione results in decreased expression of SS18 mRNA

NCBI chr18:5,773,042...5,835,696
Ensembl chr18:5,773,042...5,835,333

G

small RNA binding exonuclease protection factor La

decreases expression

1,2-dithiol-3-thione results in decreased expression of SSB mRNA

NCBI chr 3:75,024,385...75,034,016
Ensembl chr 3:54,616,619...54,626,203

G

single stranded DNA binding protein 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of SSBP1 mRNA

NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135

G

somatostatin receptor 1

increases expression

1,2-dithiol-3-thione results in increased expression of SSTR1 mRNA

NCBI chr 6:81,567,237...81,571,759
Ensembl chr 6:75,832,530...75,836,802

G

ST13, Hsp70 interacting protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of ST13 mRNA

NCBI chr 7:112,891,007...112,925,727
Ensembl chr 7:112,844,375...112,925,945

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

increases expression

1,2-dithiol-3-thione results in increased expression of ST3GAL5 mRNA

NCBI chr 4:104,134,613...104,192,558
Ensembl chr 4:104,134,613...104,192,558

G

ST6 beta-galactoside alpha-2,6-sialyltransferase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ST6GAL1 mRNA

NCBI chr11:91,031,481...91,158,111
Ensembl chr11:77,526,837...77,653,310

G

signal transducer and activator of transcription 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of STAT1 mRNA

NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:49,419,340...49,588,540

G

signal transducer and activator of transcription 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of STAT3 mRNA

NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057

G

serine/threonine kinase 25

decreases expression

1,2-dithiol-3-thione results in decreased expression of STK25 mRNA

NCBI chr 9:94,161,834...94,174,095
Ensembl chr 9:94,161,836...94,174,244

G

serine/threonine kinase 38

decreases expression

1,2-dithiol-3-thione results in decreased expression of STK38 mRNA

NCBI chr20:7,034,245...7,067,803
Ensembl chr20:7,034,242...7,068,198

G

stathmin 4

increases expression

1,2-dithiol-3-thione results in increased expression of STMN4 mRNA

NCBI chr15:40,541,305...40,559,253
Ensembl chr15:40,541,357...40,559,253

G

steroid sulfatase

decreases expression

1,2-dithiol-3-thione results in decreased expression of STS mRNA

NCBI chr X:46,102,524...46,110,868
Ensembl chr X:42,225,372...42,233,402

G

syntaxin 8

decreases expression

1,2-dithiol-3-thione results in decreased expression of STX8 mRNA

NCBI chr10:52,655,643...52,900,048
Ensembl chr10:52,654,990...52,894,993

G

sulfotransferase family 1C member 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of SULT1C1 mRNA

NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030

G

sulfotransferase family 2A member 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of SULT2A1 mRNA

NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134

G

small ubiquitin-like modifier 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of SUMO1 mRNA

NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761

G

supervillin

decreases expression

1,2-dithiol-3-thione results in decreased expression of SVIL mRNA

NCBI chr17:52,648,502...52,844,114
Ensembl chr17:52,648,502...52,793,404

G

transgelin 3

increases expression

1,2-dithiol-3-thione results in increased expression of TAGLN3 mRNA

NCBI chr11:55,099,887...55,113,457
Ensembl chr11:55,099,743...55,113,485

G

TBC1 domain family, member 23

decreases expression

1,2-dithiol-3-thione results in decreased expression of TBC1D23 mRNA

NCBI chr11:43,303,355...43,361,507
Ensembl chr11:43,303,355...43,361,503

G

TANK-binding kinase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of TBK1 mRNA

NCBI chr 7:58,963,319...58,996,357
Ensembl chr 7:57,077,830...57,110,892

G

tandem C2 domains, nuclear

decreases expression

1,2-dithiol-3-thione results in decreased expression of TC2N mRNA

NCBI chr 6:120,761,112...120,856,835
Ensembl chr 6:120,761,119...120,849,326

G

t-complex 11 like 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of TCP11L2 mRNA

NCBI chr 7:19,150,241...19,185,135
Ensembl chr 7:19,150,252...19,185,095

G

tryptophan 2,3-dioxygenase

decreases expression

1,2-dithiol-3-thione results in decreased expression of TDO2 mRNA

NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511

G

terminal nucleotidyltransferase 4A

decreases expression

1,2-dithiol-3-thione results in decreased expression of TENT4A mRNA

NCBI chr 1:33,765,949...33,799,405
Ensembl chr 1:33,765,672...33,799,433

G

transferrin

increases expression

1,2-dithiol-3-thione results in increased expression of TF mRNA

NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:103,767,995...103,816,511

G

TIMP metallopeptidase inhibitor 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of TIMP2 mRNA

NCBI chr10:104,041,604...104,089,214
Ensembl chr10:103,531,505...103,590,611

G

tight junction protein 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of TJP1 mRNA

NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:118,849,838...119,094,432

G

triokinase and FMN cyclase

increases expression

1,2-dithiol-3-thione results in increased expression of TKFC mRNA

NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737

G

transketolase

increases expression

1,2-dithiol-3-thione results in increased expression of TKT mRNA

NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,723,762...5,748,698

G

TLE family member 1, transcriptional corepressor

decreases expression

1,2-dithiol-3-thione results in decreased expression of TLE1 mRNA

NCBI chr 5:85,851,827...85,934,806
Ensembl chr 5:85,851,827...85,934,774

G

thymosin, beta 10

decreases expression

1,2-dithiol-3-thione results in decreased expression of TMSB10 mRNA

NCBI chr 4:105,009,959...105,011,095
Ensembl chr 4:105,009,212...105,011,028

G

thiol methyltransferase 1B

increases expression

1,2-dithiol-3-thione results in increased expression of TMT1B mRNA

NCBI chr 7:1,973,334...1,975,980
Ensembl chr 7:1,388,879...1,391,526

G

TNF superfamily member 13

decreases expression

1,2-dithiol-3-thione results in decreased expression of TNFSF13 mRNA

NCBI chr10:54,898,805...54,901,815
Ensembl chr10:54,400,065...54,403,042

G

tankyrase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of TNKS2 mRNA

NCBI chr 1:234,567,888...234,621,079
Ensembl chr 1:234,567,858...234,621,079

G

tensin 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of TNS1 mRNA

NCBI chr 9:75,491,886...75,702,853
Ensembl chr 9:75,495,814...75,703,225

G

translocase of outer mitochondrial membrane 20

decreases expression

1,2-dithiol-3-thione results in decreased expression of TOMM20 mRNA

NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198

G

DNA topoisomerase II alpha

increases expression

1,2-dithiol-3-thione results in increased expression of TOP2A mRNA

NCBI chr10:84,441,954...84,473,093
Ensembl chr10:83,945,735...83,976,874

G

tropomyosin 1

increases expression

1,2-dithiol-3-thione results in increased expression of TPM1 mRNA

NCBI chr 8:76,516,654...76,543,661
Ensembl chr 8:67,635,479...67,662,802

G

tropomyosin 3

increases expression

1,2-dithiol-3-thione results in increased expression of TPM3 mRNA

NCBI chr 2:177,812,534...177,842,661
Ensembl chr 2:175,517,226...175,545,013

G

tripeptidyl peptidase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of TPP2 mRNA

NCBI chr 9:46,046,712...46,128,157
Ensembl chr 9:46,046,632...46,128,157

G

tyrosylprotein sulfotransferase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of TPST2 mRNA

NCBI chr12:44,321,875...44,363,892
Ensembl chr12:44,321,875...44,362,329

G

transformer 2 beta

decreases expression

1,2-dithiol-3-thione results in decreased expression of TRA2B mRNA

NCBI chr11:78,788,880...78,807,252
Ensembl chr11:78,788,884...78,807,249

G

TNF receptor-associated protein 1

increases expression

1,2-dithiol-3-thione results in increased expression of TRAP1 mRNA

NCBI chr10:11,971,259...12,005,306
Ensembl chr10:11,464,821...11,498,981

G

trafficking protein particle complex subunit 3

increases expression

1,2-dithiol-3-thione results in increased expression of TRAPPC3 mRNA

NCBI chr 5:138,559,238...138,572,825
Ensembl chr 5:138,557,754...138,572,819

G

trafficking protein particle complex subunit 6B

decreases expression

1,2-dithiol-3-thione results in decreased expression of TRAPPC6B mRNA

NCBI chr 6:76,740,898...76,752,035
Ensembl chr 6:76,740,898...76,752,024

G

tribbles pseudokinase 3

increases expression

1,2-dithiol-3-thione results in increased expression of TRIB3 mRNA

NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497

G

tripartite motif containing 63

increases expression

1,2-dithiol-3-thione results in increased expression of TRIM63 mRNA

NCBI chr 5:146,533,492...146,547,332
Ensembl chr 5:146,533,507...146,547,322

G

TRIO and F-actin binding protein

increases expression

1,2-dithiol-3-thione results in increased expression of TRIOBP mRNA

NCBI chr 7:110,505,916...110,569,301
Ensembl chr 7:110,506,248...110,562,474

G

transient receptor potential cation channel, subfamily V, member 1

increases expression

1,2-dithiol-3-thione results in increased expression of TRPV1 mRNA

NCBI chr10:58,349,936...58,375,021
Ensembl chr10:57,851,428...57,876,513

G

TSC22 domain family, member 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of TSC22D1 mRNA

NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958

G

tetraspanin 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of TSPAN3 mRNA

NCBI chr 8:56,546,067...56,569,815
Ensembl chr 8:56,546,069...56,569,880

G

tetratricopeptide repeat domain 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of TTC3 mRNA

NCBI chr11:33,689,119...33,788,976
Ensembl chr11:33,688,952...33,788,975

G

alpha tocopherol transfer protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of TTPA mRNA

NCBI chr 5:33,497,537...33,518,936
Ensembl chr 5:33,497,137...33,518,073

G

transthyretin

decreases expression

1,2-dithiol-3-thione results in decreased expression of TTR mRNA

NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008

G

tubulin, alpha 1A

increases expression

1,2-dithiol-3-thione results in increased expression of TUBA1A mRNA

NCBI chr 7:131,992,151...131,996,850
Ensembl chr 7:130,081,032...130,196,186

G

tubulin, beta 3 class III

increases expression

1,2-dithiol-3-thione results in increased expression of TUBB3 mRNA

NCBI chr19:68,365,687...68,374,741
Ensembl chr19:51,457,184...51,466,243

G

tubulin, beta 5 class I

increases expression

1,2-dithiol-3-thione results in increased expression of TUBB5 mRNA

NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940

G

thioredoxin 1

multiple interactions

[1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] inhibits the reaction [Hydrogen Peroxide results in increased oxidation of TXN1 protein]; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of TXN1 mRNA

NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:72,711,933...72,724,629

G

thioredoxin 2

multiple interactions

[1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] inhibits the reaction [Hydrogen Peroxide results in increased oxidation of TXN2 protein]; [1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of TXN2 mRNA

NCBI chr 7:111,377,338...111,390,940
Ensembl chr 7:109,496,761...109,510,359

G

thioredoxin interacting protein

decreases expression

1,2-dithiol-3-thione results in decreased expression of TXNIP mRNA

NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:184,092,991...184,096,886

G

thioredoxin-like 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of TXNL1 mRNA

NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266

G

thioredoxin reductase 1

multiple interactions

[1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of TXNRD1 mRNA
1,2-dithiol-3-thione results in increased expression of and results in increased activity of TXNRD1 protein

PMID:22495766 PMID:25179160

NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:20,830,045...20,907,863

G

thioredoxin reductase 2

multiple interactions

[1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of TXNRD2 mRNA

NCBI chr11:96,024,321...96,072,475
Ensembl chr11:82,519,999...82,568,156

G

ubiquitin A-52 residue ribosomal protein fusion product 1

increases expression

1,2-dithiol-3-thione results in increased expression of UBA52 mRNA

NCBI chr16:18,952,583...18,954,780
Ensembl chr16:18,900,616...18,920,807

G

ubiquitin-conjugating enzyme E2B

decreases expression

1,2-dithiol-3-thione results in decreased expression of UBE2B mRNA

NCBI chr10:36,248,434...36,263,379
Ensembl chr10:36,248,438...36,264,665

G

ubiquitin-conjugating enzyme E2D 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of UBE2D2 mRNA

NCBI chr18:27,364,325...27,406,322
Ensembl chr18:27,364,303...27,406,181

G

ubiquitin-conjugating enzyme E2K

increases expression

1,2-dithiol-3-thione results in increased expression of UBE2K mRNA

NCBI chr14:42,658,016...42,718,899
Ensembl chr14:42,658,016...42,718,630

G

ubiquitin conjugating enzyme E2 Q2

decreases expression

1,2-dithiol-3-thione results in decreased expression of UBE2Q2 mRNA

NCBI chr 8:55,518,402...55,578,342
Ensembl chr 8:55,519,147...55,577,212

G

ubiquitin protein ligase E3 component n-recognin 5

decreases expression

1,2-dithiol-3-thione results in decreased expression of UBR5 mRNA

NCBI chr 7:69,115,216...69,224,843
Ensembl chr 7:69,116,761...69,224,903

G

UDP-glucose 6-dehydrogenase

increases expression

1,2-dithiol-3-thione results in increased expression of UGDH mRNA

NCBI chr14:43,202,480...43,226,002
Ensembl chr14:42,848,854...42,872,354

G

UDP glycosyltransferase 1 family, polypeptide A3

decreases expression

1,2-dithiol-3-thione results in decreased expression of UGT1A5 mRNA

NCBI chr 9:96,228,134...96,256,264
Ensembl chr 9:88,713,184...88,808,465

G

UDP glycosyltransferase 2 family, polypeptide B

increases expression

1,2-dithiol-3-thione results in increased expression of UGT2B mRNA

NCBI chr14:20,630,572...20,665,062
Ensembl chr14:20,630,250...20,651,776

G

UDP glucuronosyltransferase 2 family, polypeptide B1

increases expression

1,2-dithiol-3-thione results in increased expression of UGT2B1 mRNA; 1,2-dithiol-3-thione results in increased expression of UGT2B4 mRNA

PMID:19162173 PMID:19695238

NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,024,006...21,035,986

G

unc-51 like autophagy activating kinase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of ULK2 mRNA

NCBI chr10:46,951,038...47,029,844
Ensembl chr10:46,454,030...46,530,407

G

unc-119 lipid binding chaperone

decreases expression

1,2-dithiol-3-thione results in decreased expression of UNC119 mRNA

NCBI chr10:63,237,862...63,243,339
Ensembl chr10:63,237,903...63,243,339

G

ubiquitin specific peptidase 14

increases expression

1,2-dithiol-3-thione results in increased expression of USP14 mRNA

NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519

G

vesicle-associated membrane protein 2

increases expression

1,2-dithiol-3-thione results in increased expression of VAMP2 mRNA

NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809

G

vesicle-associated membrane protein 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of VAMP3 mRNA

NCBI chr 5:161,498,109...161,508,704
Ensembl chr 5:161,498,109...161,508,751

G

vascular cell adhesion molecule 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of VCAM1 mRNA

NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958

G

vascular endothelial growth factor A

decreases expression

1,2-dithiol-3-thione results in decreased expression of VEGFA mRNA

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641

G

von Hippel-Lindau tumor suppressor

decreases expression

1,2-dithiol-3-thione results in decreased expression of VHL mRNA

NCBI chr 4:148,328,099...148,334,992
Ensembl chr 4:146,772,468...146,779,377

G

vimentin

decreases expression

1,2-dithiol-3-thione results in decreased expression of VIM mRNA

NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187

G

vacuole membrane protein 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of VMP1 mRNA

NCBI chr10:71,903,223...72,002,337
Ensembl chr10:71,405,452...71,505,007

G

VPS29 retromer complex component

decreases expression

1,2-dithiol-3-thione results in decreased expression of VPS29 mRNA

NCBI chr12:34,208,911...34,217,977
Ensembl chr12:34,207,263...34,217,964

G

VPS33B, late endosome and lysosome associated

increases expression

1,2-dithiol-3-thione results in increased expression of VPS33B mRNA

NCBI chr 1:143,633,167...143,656,228
Ensembl chr 1:134,223,949...134,246,970

G

vacuolar protein sorting 45 homolog

increases expression

1,2-dithiol-3-thione results in increased expression of VPS45 mRNA

NCBI chr 2:183,555,919...183,616,312
Ensembl chr 2:183,555,921...183,616,295

G

WD repeat and FYVE domain containing 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of WDFY3 mRNA

NCBI chr14:7,873,946...8,115,002
Ensembl chr14:7,606,628...7,810,482

G

xylosyltransferase 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of XYLT2 mRNA

NCBI chr10:80,102,776...80,116,346
Ensembl chr10:79,606,007...79,619,391

G

Y box binding protein 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of YBX1 mRNA

NCBI chr 5:132,882,137...132,898,885
Ensembl chr 5:132,882,145...132,898,862

G

Y box binding protein 3

decreases expression

1,2-dithiol-3-thione results in decreased expression of YBX3 mRNA

NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161

G

YTH N6-methyladenosine RNA binding protein C1

decreases expression

1,2-dithiol-3-thione results in decreased expression of YTHDC1 mRNA

NCBI chr14:21,185,438...21,215,934
Ensembl chr14:21,185,440...21,216,028

G

YTH N6-methyladenosine RNA binding protein F3

decreases expression

1,2-dithiol-3-thione results in decreased expression of YTHDF3 mRNA

NCBI chr 2:98,350,304...98,384,608
Ensembl chr 2:98,350,588...98,384,606

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

decreases expression

1,2-dithiol-3-thione results in decreased expression of YWHAQ mRNA

NCBI chr 6:46,664,358...46,694,875
Ensembl chr 6:40,935,949...40,966,273

G

zinc finger AN1-type containing 6

decreases expression

1,2-dithiol-3-thione results in decreased expression of ZFAND6 mRNA

NCBI chr 1:138,581,002...138,652,052
Ensembl chr 1:138,581,002...138,651,939

G

zinc finger protein 354A

decreases expression

1,2-dithiol-3-thione results in decreased expression of ZFP354A mRNA

NCBI chr10:35,396,242...35,408,069
Ensembl chr10:35,396,231...35,408,068

G

zinc finger protein 36

decreases expression

1,2-dithiol-3-thione results in decreased expression of ZFP36 mRNA

NCBI chr 1:92,796,628...92,799,108
Ensembl chr 1:83,669,084...83,671,564

G

zinc finger protein 36, C3H type-like 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ZFP36L1 mRNA

NCBI chr 6:104,663,396...104,669,815
Ensembl chr 6:98,930,718...98,935,748

G

zinc finger protein 37

decreases expression

1,2-dithiol-3-thione results in decreased expression of ZFP37 mRNA

NCBI chr 5:75,598,732...75,638,896
Ensembl chr 5:75,598,732...75,638,942

G

zinc finger protein 386 (Kruppel-like)

decreases expression

1,2-dithiol-3-thione results in decreased expression of ZFP386 mRNA

NCBI chr 6:136,966,547...136,984,013
Ensembl chr 6:136,966,586...136,983,441

G

zymogen granule protein 16

increases expression

1,2-dithiol-3-thione results in increased expression of ZG16 mRNA

NCBI chr 1:181,657,722...181,660,079
Ensembl chr 1:181,657,722...181,660,079

G

zinc finger RANBP2-type containing 2

decreases expression

1,2-dithiol-3-thione results in decreased expression of ZRANB2 mRNA

NCBI chr 2:246,573,110...246,586,942
Ensembl chr 2:246,573,166...246,586,942

G

zinc finger containing ubiquitin peptidase 1

decreases expression

1,2-dithiol-3-thione results in decreased expression of ZUP1 mRNA

NCBI chr20:30,785,226...30,815,377
Ensembl chr20:30,785,227...30,815,306

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19904
chemical entity	19902
atom	19902
nonmetal atom	19825
sulfur atom	17780
sulfur molecular entity	17780
organosulfur compound	17475
organosulfur heterocyclic compound	10044
dithiole	902
1,2-dithiole	902
3H-1,2-dithiole-3-thione	853
Path 2
Term	Annotations
CHEBI ontology	19904
subatomic particle	19902
composite particle	19902
hadron	19902
baryon	19902
nucleon	19902
atomic nucleus	19902
atom	19902
main group element atom	19841
p-block element atom	19841
carbon group element atom	19779
carbon atom	19776
organic molecular entity	19776
organic molecule	19730
organic cyclic compound	19522
organic heterocyclic compound	18896
organic heteromonocyclic compound	17825
dithiole	902
1,2-dithiole	902
3H-1,2-dithiole-3-thione	853

paths to the root