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GENE - TERM ANNOTATION REPORT

RGD ID: 61888
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Map2k2
Name: mitogen activated protein kinase kinase 2
Acc ID: GO:0004708
Term: MAP kinase kinase activity
Definition: Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a T-X-Y motif in the activation loop of a MAP kinase (MAPK) substrate.
Definition Source(s): PMID:12623839, PMID:38270553
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map2k2 IDA 61657RGD  
Map2k2 IDA 2298674RGD  
Map2k2enablesISOMAP2K2 (Homo sapiens)1624291RGD PMID:8388392

PMID:8388392
Map2k2enablesISOMap2k2 (Mus musculus)1624291RGD PMID:8297798

PMID:8297798
Map2k2enablesIEAUniProtKB:P36507 or ensembl:ENSP000002629481600115EnsemblGO_REF:0000107

GO_REF:0000107
Map2k2enablesIEAUniProtKB:Q63932 or ensembl:ENSMUSP000001211111600115EnsemblGO_REF:0000107

GO_REF:0000107
Map2k2enablesIBACGD:CAL0000184846 or FB:FBgn0010269 or FB:FBgn0261524 or MGI:1346345 or MGI:1346866 or MGI:1346867 or MGI:1346868 or MGI:1346870 or MGI:1346871 or PANTHER:PTN000684494 or PomBase:SPAC1D4.13 or PomBase:SPBC409.07c or PomBase:SPBC543.07 or Map2k7 (Rattus norvegicus) or Map2k2 (Rattus norvegicus) or Map2k6 (Rattus norvegicus) or Map2k1 (Rattus norvegicus) or SGD:S000002318 or SGD:S000003664 or TAIR:locus:2170578 or UniProtKB:O14733 or UniProtKB:P36507 or UniProtKB:P46734 or UniProtKB:P52564 or UniProtKB:Q02750 or UniProtKB:Q5BEU9 or WB:WBGene00002177 or WB:WBGene00003185 or WB:WBGene000047581600115GO_CentralGO_REF:0000033

GO_REF:0000033
Map2k2enablesIEAARBA:ARBA000435551600115UniProtGO_REF:0000117

GO_REF:0000117
Map2k2enablesIEAEC:2.7.12.21600115UniProtGO_REF:0000003

GO_REF:0000003
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