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GENE - TERM ANNOTATION REPORT

RGD ID: 3952
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vcam1
Name: vascular cell adhesion molecule 1
Acc ID: DOID:10763
Term: hypertension
Definition: An artery disease characterized by chronic elevated blood pressure in the arteries. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Hypertension "DO" "DO", https://www.ncbi.nlm.nih.gov/pubmed/24352797 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vcam1disease_progressionIAGP 1643008RGDassociated with SHRSP;mRNA,protein:increased expression:kidney, membrane fraction (rat) 
Vcam1 IEP 2313107RGDmRNA:increased expression:multiple organs 
Vcam1 ISOVCAM1 (Homo sapiens)7241235RGDassociated with Diabetes Mellitus, Type1; protein:increased expression:serum: 
Vcam1 ISOVCAM1 (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:11834524 PMID:19018797
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