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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:hypertension
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Accession:DOID:10763 term browser browse the term
Definition:Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Synonyms:exact_synonym: HTN;   High Blood Pressure;   High Blood Pressures;   hyperpiesia;   vascular hypertensive disorder
 related_synonym: hypertensive disease;   increased aldosterone to renin ratio
 primary_id: MESH:D006973
 xref: ICD9CM:401-405.99;   NCI:C3117
For additional species annotation, visit the Alliance of Genome Resources.


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hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IDA RGD PMID:1570022 RGD:1598531 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17272743 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 ISO associated with obesity;DNA:polymorphism:exon: RGD PMID:11030411 RGD:737749 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 IEP protein:decreased expression:aorta RGD PMID:15964031, PMID:18471810 RGD:1598644, RGD:2301909 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase susceptibility ISO associated with COVID-19; DNA:polymorphism:cds:allele A (human) RGD PMID:32379894 RGD:35668862 NCBI chr 3:4,374,679...4,394,374
Ensembl chr 3:4,374,602...4,394,428
JBrowse link
G Ace angiotensin I converting enzyme susceptibility
treatment
ISO
IEP
IMP
IDA
DNA:polymorphism
CTD Direct Evidence: marker/mechanism
protein:increased activity:lung (rat)
CTD PMID:15773232, PMID:17473847, PMID:20237592, PMID:27847271, PMID:17283861, PMID:16203874, PMID:24342267, PMID:3006710, PMID:15118671, PMID:17392119 RGD:1601114, RGD:1581743, RGD:11039415, RGD:8157611, RGD:1331525, RGD:1601113 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 treatment ISO
IEP
associated with Metabolic Syndrome X (MeSH:D024821)
CTD Direct Evidence: marker/mechanism|therapeutic
mRNA, protein:decreased expression:aorta
CTD PMID:12075344, PMID:15833808, PMID:17473847, PMID:18391097, PMID:19221212, PMID:20559404, PMID:21859683, PMID:16459167, PMID:20854846, PMID:16788004, PMID:17345786 RGD:1642828, RGD:9685442, RGD:9685435, RGD:9685433 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 IAGP RGD PMID:8094726, PMID:8507454 RGD:61050, RGD:634023 NCBI chr 1:189,514,504...189,541,233
Ensembl chr 1:189,514,553...189,541,224
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 IEP RGD PMID:16343576 RGD:1598724 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
JBrowse link
G Ada adenosine deaminase IDA RGD PMID:9605386 RGD:1624292 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Adamts16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 IMP RGD PMID:23185005 RGD:9685162 NCBI chr 1:35,067,268...35,200,530
Ensembl chr 1:35,067,490...35,198,939
JBrowse link
G Adamts16em1Bj ADAM metallopeptidase with thrombospondin type 1 motif, 16; ZFN mutant1,Bj IMP RGD PMID:23185005 RGD:9685162
G Adcy5 adenylate cyclase 5 ISO
IEP
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:heart left ventricle
CTD PMID:12717102, PMID:12717102 RGD:13464134 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320
JBrowse link
G Add1 adducin 1 IAGP
ISO
IDA
CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :p.G460W (human)
CTD PMID:15773232, PMID:19199261, PMID:15474463, PMID:8543181, PMID:9149697 RGD:1302895, RGD:631736, RGD:1624953 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496
JBrowse link
G Add2 adducin 2 no_association IDA
ISO
DNA:SNP: :rs4852706 (human)
DNA:polymorphism
RGD
GAD
PMID:2059221, PMID:24652215, PMID:15118671, PMID:16497648 RGD:631712, RGD:10047131, RGD:1331525, RGD:1625293 NCBI chr 4:117,691,294...117,887,556
Ensembl chr 4:117,743,710...117,882,464
JBrowse link
G Add3 adducin 3 IDA RGD PMID:12364392 RGD:704369 NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:12860835 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adm adrenomedullin IEP
ISO
mRNA, protein:increased expression:myocardium, aorta
protein:increased expression:plasma
RGD PMID:16450076, PMID:16625237 RGD:1625300, RGD:1625298 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adora1 adenosine A1 receptor treatment
no_association
IMP
IDA
ISO
associated with diabetes mellitus, experimental RGD PMID:8998253, PMID:9597368, PMID:15257174 RGD:1625366, RGD:1625365, RGD:1625367 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora2a adenosine A2a receptor no_association ISO RGD
GAD
PMID:15257174, PMID:15118671 RGD:1625367, RGD:1331525 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adra1a adrenoceptor alpha 1A IEP
ISO
mRNA:decreased expression:aorta RGD PMID:16371063, PMID:19011682 RGD:1625770, RGD:5688340 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Adra1b adrenoceptor alpha 1B ISO RGD PMID:16095979 RGD:1625771 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Adra2a adrenoceptor alpha 2A no_association ISO
IEP
DNA:polymorphism
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:adrenal gland medulla
CTD PMID:10694191, PMID:16636200, PMID:20691504 RGD:1625183, RGD:6480490 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Adra2b adrenoceptor alpha 2B ISO
IMP
DNA:polymorphism (human) RGD PMID:18953403, PMID:17070424 RGD:2313541, RGD:2313548 NCBI chr 3:119,805,941...119,809,987
Ensembl chr 3:119,805,941...119,809,987
JBrowse link
G Adrb1 adrenoceptor beta 1 IEP
ISO
protein:increased expression:aorta
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 2;
CTD PMID:9260993, PMID:10673262, PMID:19060223, PMID:20398560 RGD:5129127, RGD:7241549 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb2 adrenoceptor beta 2 no_association
susceptibility
ISO
IEP
DNA:polymorphisms: :p.R16G, p.Q27E
DNA:polymorphisms: :pG16R, p.Q27E, p.T164I (human)
associated with Kidney Failure, Chronic; DNA:SNP:cds:p.R16G (human)
DNA:polymorphisms: :46A>G, 79C>G (human)
RGD
GAD
PMID:17221209, PMID:16041242, PMID:15118671, PMID:2471888, PMID:20484896, PMID:20739939, PMID:16685203 RGD:1601119, RGD:1578728, RGD:1331525, RGD:7175287, RGD:7175066, RGD:4144883, RGD:1601123 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Adrb3 adrenoceptor beta 3 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :p.W64R (human) RGD PMID:10981554 RGD:2313166 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP protein:increased expression:kidney RGD PMID:19018797 RGD:2325653 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agt angiotensinogen treatment
no_association
susceptibility
IEP
ISO
IDA
IMP
protein:increased expression:plasma, urine
CTD Direct Evidence: marker/mechanism|therapeutic
DNA:polymorphisms: :p.T174M, p.M235T (human)
DNA:polymorphisms: :-6G>A, p.M235T, p.T174M
DNA:polymorphism: :p.M235T
DNA:polymorphism:promoter:-20C>A (human)
DNA:polymorphism: :p.M268T (human)
CTD PMID:43064, PMID:1394429, PMID:1432030, PMID:1849535, PMID:1860718, PMID:1875449, PMID:2831029, PMID:2835134, PMID:3158602, PMID:6742791, PMID:7323490, PMID:8021468, PMID:8109997, PMID:8505092, PMID:9024144, PMID:9260993, PMID:10400907, PMID:10526905, PMID:11459117, PMID:11501062, PMID:12084390, PMID:12121858, PMID:12414515, PMID:12600921, PMID:12676074, PMID:14751847, PMID:15243307, PMID:15302986, PMID:15699457, PMID:15833808, PMID:15851630, PMID:16618834, PMID:16788141, PMID:16868307, PMID:17272743, PMID:17537837, PMID:17989111, PMID:18420994, PMID:18679781, PMID:18768397, PMID:18785976, PMID:18847324, PMID:19109942, PMID:19133994, PMID:19373235, PMID:19770776, PMID:19858406, PMID:20231528, PMID:20429690, PMID:20713914, PMID:20811386, PMID:20837116, PMID:20937366, PMID:21289285, PMID:21393355, PMID:21420289, PMID:21501650, PMID:22083158, PMID:22214961, PMID:22452651, PMID:22753205, PMID:22982863, PMID:24342267, PMID:24347665, PMID:24386282, PMID:24935938, PMID:24965170, PMID:25139994, PMID:25259750, PMID:25398788, PMID:25874449, PMID:26564064, PMID:26781276, PMID:27225954, PMID:27678262, PMID:27798352, PMID:27889505, PMID:30354818, PMID:31016362, PMID:31098697, PMID:21346625, PMID:24342267, PMID:21865264, PMID:19932924, PMID:9622148, PMID:19779471, PMID:15118671, PMID:1394429, PMID:12468106, PMID:16514903, PMID:17334527, PMID:16739866, PMID:17161775, PMID:21312059 RGD:5129176, RGD:11039415, RGD:8549470, RGD:8549469, RGD:8549458, RGD:8548902, RGD:1331525, RGD:1300393, RGD:1358275, RGD:1601143, RGD:1601130, RGD:1601141, RGD:1601139, RGD:5129166 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a no_association
susceptibility
IMP
ISO
IEP
associated with Sleep Apnea Syndromes
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:aortic endothelial cell
DNA:polymorphism:3' utr:1166A>C
DNA:polymorphism:3' utr:g.1166A>C
CTD PMID:8952600, PMID:19047579, PMID:23603059, PMID:27292124, PMID:21040717, PMID:9622148, PMID:15118671, PMID:8181542, PMID:9456365, PMID:16519598, PMID:21346625 RGD:5129169, RGD:8549458, RGD:1331525, RGD:5147456, RGD:1601152, RGD:1601148, RGD:5129176 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Agtr1b angiotensin II receptor, type 1b IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:22728133, PMID:27847271, PMID:10994756 RGD:1598885 NCBI chr 2:105,149,020...105,224,335
Ensembl chr 2:105,149,020...105,224,295
JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP
ISO
IEP
associated with Sleep Apnea Syndromes
CTD Direct Evidence: marker/mechanism
mRNA, protein:decreased expression:kidney
CTD PMID:15710752, PMID:21040717, PMID:11924718, PMID:19680135 RGD:5129169, RGD:6903865, RGD:6903372 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Agtrap angiotensin II receptor-associated protein IEP protein:increased expression:kidney RGD PMID:18725581 RGD:2314351 NCBI chr 5:164,888,069...164,898,387
Ensembl chr 5:164,886,813...164,898,420
JBrowse link
G Ahcy adenosylhomocysteinase ISO associated with hyperhomocysteinemia RGD PMID:16815886 RGD:1601153 NCBI chr 3:150,587,833...150,603,057
Ensembl chr 3:150,587,833...150,603,082
JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21115475 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akt1 AKT serine/threonine kinase 1 IDA protein:increased serine phosphorylation:kidney RGD PMID:23323219 RGD:10041025 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 IEP mRNA:increased expression:cerebral cortex (rat) RGD PMID:12902546 RGD:2313350 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alad aminolevulinate dehydratase no_association ISO DNA:polymorphism
CTD Direct Evidence: marker/mechanism
CTD PMID:20123609, PMID:11335187 RGD:1601156 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Alb albumin ISO CTD Direct Evidence: therapeutic CTD PMID:2526952 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member susceptibility
no_association
ISO RGD PMID:11510748, PMID:12484509 RGD:1601164, RGD:1601163 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type IEP mRNA:decreased expression:medulla oblongata RGD PMID:16445702 RGD:5509789 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22467300 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Alox5 arachidonate 5-lipoxygenase IDA RGD PMID:16331105 RGD:1626151 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Angpt1 angiopoietin 1 ISO protein:increased expression:plasma, platelet RGD PMID:16942942, PMID:18285514 RGD:1626157, RGD:2316068 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Anxa1 annexin A1 IEP
ISO
protein:altered localization:vascular associated smooth muscle cell
CTD Direct Evidence: marker/mechanism
CTD PMID:22228705, PMID:16109804 RGD:1599668 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Aoc1 amine oxidase, copper containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:6218830 NCBI chr 4:78,496,043...78,515,582
Ensembl chr 4:78,496,043...78,515,584
JBrowse link
G Aoc3 amine oxidase, copper containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23154672 NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313
JBrowse link
G Apln apelin IEP mRNA:decreased expression:aorta, heart RGD PMID:15664402 RGD:1626176 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210
JBrowse link
G Apoa1 apolipoprotein A1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:18224302, PMID:23401751 RGD:7241867 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apob apolipoprotein B ISO GAD PMID:15118671 RGD:1331525 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoe apolipoprotein E onset ISO
IEP
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:multiple (rat)
CTD PMID:20720404, PMID:22228705, PMID:15118671, PMID:20585107 RGD:1331525, RGD:6904214 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G App amyloid beta precursor protein IEP RGD PMID:29713228 RGD:13703136 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp1 aquaporin 1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:22228705, PMID:20156423 RGD:5148031 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp2 aquaporin 2 IEP protein:decreased expression:kidney medulla
protein:increased expression:kidney medulla
RGD PMID:16788141, PMID:16582573 RGD:1601242, RGD:1601243 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Aqp4 aquaporin 4 IEP RGD PMID:20156423 RGD:5148031 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Ar androgen receptor treatment IDA
ISO
IMP
CTD Direct Evidence: marker/mechanism CTD PMID:10523385, PMID:15746697, PMID:12397037 RGD:1601245, RGD:10043316 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arg1 arginase 1 IMP
IEP
mRNA:increased expression:aorta (rat) RGD PMID:18475148, PMID:17223136 RGD:4142834, RGD:1626296 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arg2 arginase 2 IMP
IEP
mRNA:increased expression:lung
mRNA:increased expression:aorta (rat)
RGD PMID:18475148, PMID:20039818, PMID:17223136 RGD:4142834, RGD:4143278, RGD:1626296 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha IEP mRNA:decreased expression:urinary bladder
protein:decreased expression:cortical collecting duct
RGD PMID:19689474, PMID:25164814 RGD:9684972, RGD:9684979 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arid1b AT-rich interaction domain 1B treatment IEP RGD PMID:17489020 RGD:9587762 NCBI chr 1:45,923,119...46,232,301
Ensembl chr 1:45,923,222...46,234,874
JBrowse link
G Arntl2 aryl hydrocarbon receptor nuclear translocator-like 2 ISO DNA:SNPs: :rs6486121, rs3789327, rs969485(human) RGD PMID:17728404 RGD:2314371 NCBI chr 4:181,103,774...181,158,415
Ensembl chr 4:181,103,774...181,214,994
JBrowse link
G Arrb2 arrestin, beta 2 IEP protein:decreased expression:rostral ventrolateral medulla RGD PMID:27861247 RGD:13506896 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Atf2 activating transcription factor 2 IDA RGD PMID:11358932 RGD:10047414 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atg7 autophagy related 7 IEP protein:increased expression:skeletal muscle RGD PMID:24119246 RGD:11557985 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Atox1 antioxidant 1 copper chaperone ISO CTD Direct Evidence: therapeutic CTD PMID:22753205 NCBI chr10:40,790,850...40,805,886
Ensembl chr10:40,790,845...40,805,941
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 IAGP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:23416519, PMID:8082931 RGD:1579862 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 susceptibility IEP
ISO
protein:decreased expression:adrenal gland cortex zone
CTD Direct Evidence: marker/mechanism
CTD PMID:16166162, PMID:16243970, PMID:11768735, PMID:11257061, PMID:16243970 RGD:1601253, RGD:1601254, RGD:1601251 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 IEP RGD PMID:11208768 RGD:68726 NCBI chr10:59,528,849...59,560,440
Ensembl chr10:59,529,785...59,560,433
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 IEP
ISO
mRNA:increased expression:vascular associated smooth muscle cell
CTD Direct Evidence: marker/mechanism
CTD PMID:19430479, PMID:20137670 RGD:2317726 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579
JBrowse link
G Atp2b3 ATPase plasma membrane Ca2+ transporting 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23416519 NCBI chr  X:157,236,400...157,312,028
Ensembl chr  X:157,239,306...157,312,028
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha IEP protein:decreased expression:heart left ventricle (rat) RGD PMID:24388463 RGD:7800726 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 IEP RGD PMID:21321306 RGD:5132599 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Avp arginine vasopressin IEP
ISO
protein:increased expression:carotid artery
CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma
CTD PMID:1663982, PMID:3346065, PMID:4040330, PMID:6367368, PMID:19133994, PMID:12623976, PMID:16582573 RGD:1601305, RGD:1601243 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Avpr1a arginine vasopressin receptor 1A IEP
ISO
mRNA, protein:increased expression:paraventricular hypothalamic nucleus
mRNA, protein:increased expression:kidney, arteriole
DNA:SNP
RGD PMID:15475662, PMID:15657301, PMID:17653244 RGD:2300330, RGD:2300322, RGD:2300319 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Avpr2 arginine vasopressin receptor 2 severity IDA RGD PMID:12072411 RGD:1298694 NCBI chr  X:156,889,006...156,892,707
Ensembl chr  X:156,889,410...156,891,213
JBrowse link
G B2m beta-2 microglobulin ISO protein:increased expression:serum RGD PMID:15957539 RGD:1601306 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Bad BCL2-associated agonist of cell death treatment IEP RGD PMID:20065158 RGD:10053702 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:20065158 RGD:10053702 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase ISO RGD PMID:12387587 RGD:1601322 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:10075388, PMID:20065158 RGD:10053702 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdkrb1 bradykinin receptor B1 IMP
IEP
ISO
RGD PMID:17988733, PMID:12025958, PMID:15643125 RGD:5129214, RGD:704378, RGD:1625732 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Bdkrb2 bradykinin receptor B2 IEP
ISO
protein:increased expression:spinal cord
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:hypothalamus
DNA:SNP:promoter:-58T>C (human)
CTD PMID:10614985, PMID:11934804, PMID:15118671, PMID:12025958, PMID:10904024 RGD:4890455, RGD:1331525, RGD:704378, RGD:4891034 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Becn1 beclin 1 IEP protein:increased expression:brain RGD PMID:23499735 RGD:11561939 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Brca1 BRCA1, DNA repair associated IEP RGD PMID:24239235 RGD:8693672 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Brs3 bombesin receptor subtype 3 ISO RGD PMID:9367152 RGD:734661 NCBI chr  X:159,484,953...159,510,944
Ensembl chr  X:159,505,344...159,511,021
JBrowse link
G C3 complement C3 IEP RGD PMID:22416803 RGD:11040890 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22949532 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22949532 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 susceptibility ISO DNA:SNP: :rs4373814(human) RGD PMID:24338417 RGD:13513987 NCBI chr17:81,673,862...82,019,219
Ensembl chr17:81,798,756...82,017,682
JBrowse link
G Calca calcitonin-related polypeptide alpha ISO CTD Direct Evidence: therapeutic CTD PMID:1849535, PMID:9887042 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Casp3 caspase 3 treatment IDA
IEP
RGD PMID:20065158, PMID:27929425 RGD:10053702, RGD:13782308 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 IEP RGD PMID:27929425 RGD:13782308 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 IEP RGD PMID:27929425 RGD:13782308 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:11479740, PMID:20667508, PMID:21593737, PMID:22228705, PMID:16716903 RGD:1580833 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 IEP
ISO
protein:increased expression:artery smooth muscle, blood vessel endothelial cell
CTD Direct Evidence: marker/mechanism
CTD PMID:1798635, PMID:17986358 RGD:2289116 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cbs cystathionine beta synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18224302 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IEP
ISO
IDA
protein:increased expression:urine
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA, protein:increased expression:kidney cortex, urine
CTD PMID:20667508, PMID:27292124, PMID:17989143, PMID:17922026, PMID:18459944 RGD:2307054, RGD:8549771, RGD:2307029 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl28 C-C motif chemokine ligand 28 no_association IEP mRNA, protein:decreased expression:kidney (rat)
protein:increased expression:kidney (rat)
RGD PMID:19829664, PMID:16840655 RGD:4892132, RGD:2298761 NCBI chr 2:52,379,341...52,403,979
Ensembl chr 2:52,379,341...52,404,246
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum RGD PMID:15668187 RGD:2307105 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccn2 cellular communication network factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16685210 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccne1 cyclin E1 IEP protein:increased expression:vascular associated smooth muscle cell RGD PMID:12847112 RGD:2289296 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEP
ISO
mRNA:increased expression:aorta (rat)
DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)
RGD PMID:20044442, PMID:12680626 RGD:4890416, RGD:1581182 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd14 CD14 molecule ISO associated with Glomerulonephritis, IGA; DNA:polymorphism: :-159C>T (human) RGD PMID:22072187 RGD:7204129 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd36 CD36 molecule IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:18587397, PMID:18587397 RGD:2300254 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd82 Cd82 molecule IEP mRNA:increased expression:thymus RGD PMID:10321446 RGD:2289422 NCBI chr 3:82,324,344...82,368,846
Ensembl chr 3:82,324,354...82,368,357
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A IEP protein:increased expression:kidney RGD PMID:18504326 RGD:2316082 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdo1 cysteine dioxygenase type 1 IEP protein:decreased expression:brain RGD PMID:6726227 RGD:2301363 NCBI chr18:40,702,027...40,716,901
Ensembl chr18:40,701,984...40,716,686
JBrowse link
G Cela2a chymotrypsin like elastase 2A ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: High blood pressure
CTD
ClinVar
PMID:21602471, PMID:31358993 NCBI chr 5:160,374,031...160,383,782
Ensembl chr 5:160,374,031...160,383,782
JBrowse link
G Cftr CF transmembrane conductance regulator ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:28603918, PMID:30311386 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Chd8 chromodomain helicase DNA binding protein 8 ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:30311386 NCBI chr15:28,612,932...28,672,574
Ensembl chr15:28,612,932...28,672,569
JBrowse link
G Chga chromogranin A no_association ISO
IEP
protein:creased expression:adrenal gland
mRNA, protein:increased expression:adrenal gland medulla, plasma
DNA:polymorphisms:promoter
RGD PMID:21061160, PMID:10803489, PMID:10803489, PMID:20113265, PMID:20729505 RGD:6906897, RGD:6907055, RGD:6907055, RGD:6906902, RGD:6906900 NCBI chr 6:126,434,226...126,445,569
Ensembl chr 6:126,434,226...126,445,568
JBrowse link
G Chi3l1 chitinase 3 like 1 IEP mRNA:increased expression:brainstem, solitary tract nucleus (rat) RGD PMID:18703386 RGD:4892597 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802
JBrowse link
G Clcnka chloride voltage-gated channel Ka ISO CTD Direct Evidence: marker/mechanism CTD PMID:18480177 NCBI chr 5:159,931,497...159,946,483
Ensembl chr 5:159,931,511...159,946,446
JBrowse link
G Clcnkb chloride voltage-gated channel Kb no_association ISO DNA:polymorphism:T481S RGD PMID:15148291, PMID:16003175 RGD:1600684, RGD:1600683 NCBI chr 5:159,950,384...159,973,576
Ensembl chr 5:159,950,392...159,962,676
JBrowse link
G Cldn16 claudin 16 IDA Protein:decreased serine phosphorylation:kidney RGD PMID:16959063 RGD:1599616 NCBI chr11:77,683,942...77,703,232
Ensembl chr11:77,681,794...77,703,255
JBrowse link
G Clock clock circadian regulator IEP mRNA:altered expression:gastrocnemius muscle (rat) RGD PMID:22076133 RGD:9686076 NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218
JBrowse link
G Clu clusterin ISO DNA:SNP:exon:866C>T (human) RGD PMID:15925890 RGD:1581195 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cma1 chymase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14620933 NCBI chr15:34,601,037...34,603,819
Ensembl chr15:34,601,037...34,603,819
JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:19133994 RGD:2314680 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:11682445 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col3a1 collagen type III alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:11682445 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col4a4 collagen type IV alpha 4 chain ISO ClinVar Annotator: match by term: Hypertension
ClinVar Annotator: match by term: High blood pressure
ClinVar PMID:24033266, PMID:25741868 NCBI chr 9:88,314,763...88,357,183
Ensembl chr 9:88,232,455...88,357,182
JBrowse link
G Col4a5 collagen type IV alpha 5 chain ISO ClinVar Annotator: match by term: Hypertension
ClinVar Annotator: match by term: High blood pressure
ClinVar PMID:9848783, PMID:11223851, PMID:17396119, PMID:19728970, PMID:19965530, PMID:20378821, PMID:21332469, PMID:24470729, PMID:25741868, PMID:26467025, PMID:26809805, PMID:26934356, PMID:28492532, PMID:28844315, PMID:29854973, PMID:30311386 NCBI chr  X:112,769,595...112,983,720
Ensembl chr  X:112,769,645...112,983,685
JBrowse link
G Comt catechol-O-methyltransferase susceptibility IEP
IDA
ISO
protein:increased expression:cerebral cortex
DNA:polymorphism: :-1187G>C, 186C>T
RGD PMID:17978496, PMID:17510509, PMID:17143180, PMID:14714585 RGD:2289729, RGD:8662344, RGD:2289742, RGD:2289787 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Corin corin, serine peptidase ISO RGD PMID:17485366, PMID:16216958 RGD:1626338, RGD:1581219 NCBI chr14:38,247,379...38,474,931
Ensembl chr14:38,247,791...38,473,648
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B IEP protein:decreased expression:heart left ventricle RGD PMID:16132109 RGD:2301377 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 IEP protein:decreased expression:liver, mitochondrion RGD PMID:19135993 RGD:2303405 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IDA corticotropin releasing hormone-induced RGD PMID:11036160 RGD:1581302 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10742107 NCBI chr 4:85,286,371...85,329,374
Ensembl chr 4:85,286,372...85,329,362
JBrowse link
G Crp C-reactive protein IEP
ISO
protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum:
CTD PMID:14620923, PMID:16680063, PMID:19770776, PMID:20667508, PMID:19905982, PMID:19056836, PMID:6720266 RGD:5131461, RGD:9586008, RGD:9491754 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Ctf1 cardiotrophin 1 ISO
IEP
protein:increased expression:plasma
mRNA:increased expression:cardiac ventricle
RGD PMID:15716706, PMID:8604995 RGD:1626411, RGD:69823 NCBI chr 1:199,162,319...199,168,296
Ensembl chr 1:199,163,086...199,168,296
JBrowse link
G Ctsc cathepsin C IEP RGD PMID:657443 RGD:1599651 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27678262 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cyba cytochrome b-245 alpha chain IDA
ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney cortex
CTD PMID:16685210, PMID:17324946, PMID:20505675, PMID:17109653, PMID:12729892, PMID:20018820 RGD:4775206, RGD:1580276, RGD:2317853 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cybb cytochrome b-245 beta chain IEP
ISO
Protein:increased expression:brain
CTD Direct Evidence: marker/mechanism
CTD PMID:16685210, PMID:21593737, PMID:27659729, PMID:27847271, PMID:12472782 RGD:1599685 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP mRNA:increased expression:hypothalamus RGD PMID:16116051 RGD:1599701 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 IEP
IAGP
mRNA:decreased expression:hypothalamus, cerebellum, cortex (rat) RGD PMID:19837774, PMID:7981756 RGD:4891156, RGD:69709
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 ISO
IMP
IEP
DNA:transition:5' utr:-344C>T (human)
mRNA:increased expression:brainstem, hippocampus, cortex (rat)
RGD PMID:10024332, PMID:18495825, PMID:19837774 RGD:4891152, RGD:2307304, RGD:4891156 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 ISO ClinVar Annotator: match by term: Aldosterone to renin ratio, increased ClinVar PMID:12213905, PMID:12788845, PMID:17003099 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP mRNA:decreased expression:ovary (rat) RGD PMID:19228890 RGD:4761326 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20634294, PMID:22995157, PMID:20634294 RGD:7257731 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 ISO
IEP
RGD PMID:19669737, PMID:18829737 RGD:6903909, RGD:6903915 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 susceptibility ISO DNA:SNP RGD PMID:17286575, PMID:20501636 RGD:1625379, RGD:7243136 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 ISO
IEP
mRNA:decreased expression:kidney cortex RGD PMID:16144986, PMID:16339392, PMID:18952718 RGD:1625567, RGD:2303383, RGD:2303381 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 IEP mRNA:decreased expression:kidney cortex RGD PMID:18952718, PMID:16339392 RGD:2303381, RGD:2303383 NCBI chr 5:133,978,953...134,008,255
Ensembl chr 5:133,978,954...134,008,255
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 IEP mRNA:increased expression:kidney RGD PMID:16182239 RGD:2301709 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
JBrowse link
G Dars2 aspartyl-tRNA synthetase 2 (mitochondrial) ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:17384640, PMID:19592391, PMID:22843165, PMID:23065766, PMID:23652419, PMID:24005482, PMID:24407472, PMID:25741868, PMID:30311386 NCBI chr13:78,857,638...78,885,464
Ensembl chr13:78,857,638...78,885,464
JBrowse link
G Dbh dopamine beta-hydroxylase resistance IEP
ISO
mRNA:increased expression:heart, adrenal gland (rat)
DNA:polymorphism:5' utr:g.-2073C>T rs1989787 (human)
RGD PMID:20596792, PMID:20814407 RGD:5129234, RGD:5129211 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 susceptibility ISO RGD PMID:16444868 RGD:1625582 NCBI chr 2:251,634,368...251,766,009
Ensembl chr 2:251,634,431...251,766,014
JBrowse link
G Dio2 iodothyronine deiodinase 2 susceptibility ISO RGD PMID:17224473 RGD:1626437 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Drd1 dopamine receptor D1 ISO RGD PMID:10948075, PMID:8636408 RGD:1580869, RGD:1300303 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 ISO DNA:polymorphism
CTD Direct Evidence: marker/mechanism
CTD PMID:11566895, PMID:15939106, PMID:11494094 RGD:1600905, RGD:1580874 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 IDA RGD PMID:11675403 RGD:1580882 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Drd5 dopamine receptor D5 ISO RGD PMID:12486173 RGD:1580887 NCBI chr14:77,220,579...77,222,006
Ensembl chr14:77,220,579...77,222,006
JBrowse link
G Dusp1 dual specificity phosphatase 1 IEP mRNA, protein:increased expression:aorta RGD PMID:9231829 RGD:2298678 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp5 dual specificity phosphatase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25397684 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Dynll1 dynein light chain LC8-type 1 treatment IMP RGD PMID:24035314 RGD:13207430 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G Ece1 endothelin converting enzyme 1 IDA
ISO
IEP
CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression,increased activity:kidney medulla
CTD PMID:12566389, PMID:12193123, PMID:10894793 RGD:1580907, RGD:7244182 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G Edn1 endothelin 1 IEP
ISO
protein:increased secretion:plasma (rat)
CTD Direct Evidence: marker/mechanism
human gene in a rat model
associated with Diabetic Nephropathies;protein:increased secretion:plasma
DNA:polymorphism:exon:p.K198N (human)
CTD PMID:7721406, PMID:8152482, PMID:8440307, PMID:10474778, PMID:10669576, PMID:11847185, PMID:12149661, PMID:12425201, PMID:12600921, PMID:15188945, PMID:15302986, PMID:15314687, PMID:15834289, PMID:17130675, PMID:20733093, PMID:11078355, PMID:18496905, PMID:17444275 RGD:4144829, RGD:8661804, RGD:2313283, RGD:1625065 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Edn2 endothelin 2 ISO mRNA:increased expression:leukocyte RGD PMID:10976780, PMID:10489105, PMID:15007037 RGD:1580916, RGD:1580917, RGD:1625402 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792
JBrowse link
G Edn3 endothelin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:2059916 NCBI chr 3:172,856,730...172,879,276
Ensembl chr 3:172,856,733...172,880,450
JBrowse link
G Ednra endothelin receptor type A IEP
ISO
IDA
associated with Uremia
CTD Direct Evidence: marker/mechanism
CTD PMID:12600921, PMID:20144075, PMID:14616768, PMID:16157796 RGD:4892284, RGD:1580950, RGD:1581830 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B IEP
IMP
associated with Uremia RGD PMID:20144075, PMID:10749572 RGD:4892284, RGD:628518 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Egfr epidermal growth factor receptor IEP mRNA, protein:increased expression:renal cortex RGD PMID:15827348 RGD:1580953 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 IMP RGD PMID:22686466 RGD:11252087 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 IEP mRNA:increased expression:heart left ventricle RGD PMID:12708758 RGD:10755511 NCBI chr 1:175,883,362...175,895,510
Ensembl chr 1:175,883,363...175,895,510
JBrowse link
G Eln elastin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17039479 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Emilin1 elastin microfibril interfacer 1 ISO RGD PMID:16530041 RGD:1580958 NCBI chr 6:26,821,249...26,829,013
Ensembl chr 6:26,821,255...26,828,972
JBrowse link
G Eng endoglin IEP mRNA:decreased expression:kidney (rat) RGD PMID:19829664 RGD:4892132 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Eno1 enolase 1 IEP RGD PMID:16485256 RGD:1598909 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Eno2 enolase 2 severity ISO protein:increased expression:serum RGD PMID:21130083 RGD:5508770 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 IEP RGD PMID:20655932 RGD:9685529 NCBI chr 3:2,617,795...2,623,818
Ensembl chr 3:2,617,805...2,623,445
JBrowse link
G Ep300 E1A binding protein p300 IEP protein:increased expression:left ventricle (rat) RGD PMID:18292809 RGD:2312265 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Ephx2 epoxide hydrolase 2 susceptibility IDA
IMP
ISO
DNA:missense mutation:cds:p.K55R (human) RGD PMID:16157792, PMID:21720266, PMID:19553349, PMID:20065888 RGD:1580985, RGD:5688733, RGD:5688730, RGD:5688727 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:1516988, PMID:10694834 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Epor erythropoietin receptor susceptibility ISO induced by erythropoietin; RGD PMID:19458615 RGD:11041646 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:13678427 NCBI chr 2:1,410,877...1,449,734
Ensembl chr 2:1,410,934...1,449,733
JBrowse link
G Esr2 estrogen receptor 2 ISO
IMP
RGD PMID:11799247, PMID:23608653, PMID:11185739, PMID:15167447 RGD:734949, RGD:7364951, RGD:1581015, RGD:1581017 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G F11 coagulation factor XI ISO CTD Direct Evidence: marker/mechanism CTD PMID:6383834 NCBI chr16:50,179,458...50,201,644
Ensembl chr16:50,179,458...50,201,698
JBrowse link
G F11r F11 receptor susceptibility ISO
IEP
DNA:SNPs: :rs790056, rs2774276 (human) RGD PMID:18067551, PMID:17420334 RGD:7488938, RGD:7488939 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612
JBrowse link
G F12 coagulation factor XII ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: High blood pressure
CTD
ClinVar
PMID:6383834, PMID:16638441, PMID:25741868, PMID:30311386 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
JBrowse link
G F2r coagulation factor II (thrombin) receptor IDA RGD PMID:9168786 RGD:1581034 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G F3 coagulation factor III, tissue factor treatment IEP RGD PMID:21423288 RGD:11341709 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G F7 coagulation factor VII ISO
IEP
protein:increased activity:plasma (human)
protein:increased activity:plasma (rat)
RGD PMID:10450539, PMID:8123879, PMID:812575 RGD:2312402, RGD:2312412, RGD:2312323 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Fabp1 fatty acid binding protein 1 ISO possibly associated with arteriosclerosis (MeSH:D001161) RGD PMID:15830271 RGD:1626441 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fabp3 fatty acid binding protein 3 susceptibility ISO DNA:SNPs RGD PMID:18437121 RGD:2307331 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
JBrowse link
G Fadd Fas associated via death domain treatment IEP RGD PMID:24355328 RGD:11344883 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fads1 fatty acid desaturase 1 IEP RGD PMID:12144877 RGD:1625415 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138
JBrowse link
G Fah fumarylacetoacetate hydrolase IEP mRNA:decreased expression:kidney RGD PMID:15731461 RGD:1559295 NCBI chr 1:146,713,663...146,736,339
Ensembl chr 1:146,713,676...146,736,261
JBrowse link
G Fbn1 fibrillin 1 IEP protein:increased expression:renal glomerulus (rat) RGD PMID:16380460 RGD:7365080 NCBI chr 3:117,569,708...117,766,160
Ensembl chr 3:117,569,697...117,766,120
JBrowse link
G Fbxw4 F-box and WD repeat domain containing 4 ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:30311386 NCBI chr 1:265,318,526...265,420,503
Ensembl chr 1:265,318,526...265,420,503
JBrowse link
G Fgf2 fibroblast growth factor 2 IEP associated with Aortic Coarctation RGD PMID:17562191 RGD:8655614 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 no_association ISO associated with trimethylaminuria, OMIM:602079 RGD PMID:9536088, PMID:16324215 RGD:1626461, RGD:1626466 NCBI chr13:80,837,418...80,856,214
Ensembl chr13:80,837,420...80,862,963
JBrowse link
G Fn1 fibronectin 1 ISO
IEP
IAGP
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:kidney (SHRSP/A3N rat)
CTD PMID:11682445, PMID:17324946, PMID:11907153, PMID:11682445 RGD:28912746, RGD:30296650 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:12044476, PMID:24039778, PMID:16696897 RGD:7242185 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxp3 forkhead box P3 treatment IEP RGD PMID:24420551 RGD:38549366 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 8:49,710,334...49,717,492
Ensembl chr 8:49,710,477...49,716,955
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:1562739, PMID:2263506, PMID:6714986, PMID:8447319, PMID:8537082, PMID:9299858, PMID:10643148, PMID:11499668, PMID:16143877, PMID:17726510, PMID:20203002, PMID:21446359, PMID:23365477, PMID:25541721, PMID:25775246, PMID:26060661, PMID:26823837, PMID:28492532, PMID:30311386 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 IEP mRNA:increased expression:brain RGD PMID:18338268 RGD:2315462 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Gal galanin and GMAP prepropeptide IEP
ISO
mRNA:decreased expression:paraventricular hypothalamic nucleus, solitary tract nucleus
CTD Direct Evidence: marker/mechanism
CTD PMID:10818254, PMID:15275958 RGD:1624333 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Gcg glucagon ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12855421 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Gck glucokinase susceptibility ISO RGD PMID:9324112 RGD:1581877 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Ghsr growth hormone secretagogue receptor ISO associated with Obesity RGD PMID:24760503 RGD:12910115 NCBI chr 2:113,065,953...113,071,265
Ensembl chr 2:113,066,885...113,070,261
JBrowse link
G Gja1 gap junction protein, alpha 1 treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:16448880, PMID:16448880, PMID:23719203 RGD:7207810, RGD:8662439 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gja4 gap junction protein, alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16448880 NCBI chr 5:145,374,688...145,377,221
Ensembl chr 5:145,374,690...145,377,221
JBrowse link
G Gja5 gap junction protein, alpha 5 treatment IDA
ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:decreased expression:artery endothelium
CTD PMID:19109587, PMID:19686729, PMID:11821709 RGD:7207417, RGD:7207848 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Gjc1 gap junction protein, gamma 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19109587 NCBI chr10:90,781,408...90,912,440
Ensembl chr10:90,781,402...90,912,287
JBrowse link
G Glp1r glucagon-like peptide 1 receptor IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:22228705, PMID:12093887 RGD:625448 NCBI chr20:9,586,075...9,626,228
Ensembl chr20:9,586,075...9,626,228
JBrowse link
G Gnai2 G protein subunit alpha i2 treatment IMP
IEP
RGD PMID:27912212, PMID:15106810 RGD:13507308, RGD:13508592 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Gnai3 G protein subunit alpha i3 treatment IEP RGD PMID:15106810 RGD:13508592 NCBI chr 2:210,896,779...210,934,733
Ensembl chr 2:210,896,656...210,934,749
JBrowse link
G Gnas GNAS complex locus ISO CTD Direct Evidence: marker/mechanism CTD PMID:9506701, PMID:12215464, PMID:15118671 RGD:1580404, RGD:1331525 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gnb3 G protein subunit beta 3 susceptibility
no_association
ISO DNA:SNP:cds:825C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:cds: 825C>T (human)
DNA:polymorphism: :multiple (human)
CTD PMID:15961981, PMID:16141801, PMID:10526907, PMID:11230982, PMID:16908025 RGD:1580410, RGD:1580408, RGD:2313206 NCBI chr 4:157,352,558...157,359,237
Ensembl chr 4:157,352,372...157,358,262
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:6350720 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr10:57,260,680...57,263,546
Ensembl chr10:57,260,680...57,263,546
JBrowse link
G Gpx1 glutathione peroxidase 1 treatment ISO
IDA
IEP
CTD Direct Evidence: marker/mechanism CTD PMID:21593737, PMID:17198913, PMID:21210316, PMID:23752977 RGD:1600704, RGD:11353777, RGD:11352825 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 treatment IEP
ISO
protein:increased expression:lymphocyte, vascular associated smooth muscle cell
CTD Direct Evidence: marker/mechanism
CTD PMID:11901213, PMID:10642272, PMID:23913704 RGD:1625788, RGD:13792716 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Grk3 G protein-coupled receptor kinase 3 IEP mRNA:increased expression:heart left ventricle, kidney (rat) RGD PMID:26248277 RGD:11535540 NCBI chr12:49,626,871...49,750,389
Ensembl chr12:49,626,871...49,746,272
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 IEP mRNA:increased expression:heart left ventricle, kidney (rat) RGD PMID:26248277 RGD:11535540 NCBI chr 1:282,265,371...282,467,842
Ensembl chr 1:282,265,370...282,462,605
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:22982863, PMID:22982863 RGD:10045670 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase ISO RGD PMID:17198913 RGD:1600704 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gstm1 glutathione S-transferase mu 1 IEP mRNA:decreased expression:kidney (rat) RGD PMID:15699453 RGD:7495838 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 IEP mRNA:decreased expression:kidney (rat) RGD PMID:18008142, PMID:12624007 RGD:2302178, RGD:631154 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24915237 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO associated with scleroderma, systemic;DNA:deletion: :
CTD Direct Evidence: marker/mechanism
CTD PMID:22228705, PMID:11477481 RGD:5490587 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gstt2 glutathione S-transferase, theta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr20:13,760,810...13,764,481
Ensembl chr20:13,760,810...13,764,475
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18339647 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918
JBrowse link
G H2ax H2A.X variant histone treatment IDA RGD PMID:24239235 RGD:8693672 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 IEP protein:increased expression:urine RGD PMID:23085980 RGD:7245484 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hdac6 histone deacetylase 6 IEP protein:increased expression, activity:heart: RGD PMID:23868068 RGD:9681716 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Hdac8 histone deacetylase 8 IEP protein:decreased expression:heart (mouse, rat) RGD PMID:28567090 RGD:13208602 NCBI chr  X:72,163,777...72,370,058
Ensembl chr  X:72,163,777...72,370,044
JBrowse link
G Hgf hepatocyte growth factor susceptibility ISO DNA:polymorphism:intron13:C/A RGD PMID:15127882, PMID:15127882 RGD:1642064, RGD:1642064 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO
IEP
Hypertension, Pregnancy-Induced;mRNA, protein:increased expression:placenta
CTD Direct Evidence: therapeutic
associated with Hypercholesterolemia;protein:increased expression:aorta
protein:increased expression:brain
CTD PMID:22349312, PMID:15862159, PMID:11882589, PMID:16955051 RGD:1626322, RGD:1626330, RGD:1626317 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 susceptibility
treatment
ISO
IDA
CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16959961, PMID:22349312, PMID:22352330, PMID:12872043, PMID:20836698, PMID:12215473 RGD:1598400, RGD:10755717, RGD:1580453 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin susceptibility
onset
ISO
IEP
DNA:polymorphism
CTD Direct Evidence: marker/mechanism
CTD PMID:16597321, PMID:7606649, PMID:23401751, PMID:8228210 RGD:1626351, RGD:7241867, RGD:1626352 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hrh2 histamine receptor H 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30310171 NCBI chr17:10,912,959...10,931,389
Ensembl chr17:10,921,507...10,952,441
JBrowse link
G Hrh3 histamine receptor H3 IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:9050021, PMID:9050021 RGD:1626409 NCBI chr 3:175,474,310...175,479,395
Ensembl chr 3:175,473,078...175,479,395
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9683905, PMID:15199296, PMID:21786805 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 IEP
ISO
associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:kidney
CTD Direct Evidence: marker/mechanism
apparent mineralocorticoid excess syndrome, OMIM:218030
CTD PMID:7670488, PMID:9683905, PMID:9707624, PMID:11082157, PMID:10792625, PMID:9683587 RGD:2308925, RGD:1625078 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 IEP mRNA:decreased expression:renal cortex (rat) RGD PMID:18430809 RGD:2292646 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 susceptibility IEP
ISO
mRNA:decreased expression:ovary (rat)
DNA:polymorphism:exon
RGD PMID:19228890, PMID:12054649 RGD:4761326, RGD:1626438
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 IEP mRNA:increased expression:hypothalamus (rat) RGD PMID:16116051 RGD:1599701 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO mRNA: increased expression: leukocyte RGD PMID:17341625 RGD:6480224 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEP mRNA:increased expression:brain, blood vessel RGD PMID:15729290, PMID:18948349 RGD:1624213, RGD:10402862 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 IEP mRNA:increased expression:aorta RGD PMID:8225534 RGD:1624258 NCBI chr 5:155,812,096...155,913,751 JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B IEP protein:increased expression:aorta RGD PMID:11882579 RGD:1626447 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A susceptibility
no_association
ISO DNA:polymorphism: :102T>C
DNA:polymorphism: :g.102T>C
RGD
GAD
PMID:11378836, PMID:15118671, PMID:15659047 RGD:1624375, RGD:1331525, RGD:1624371 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:8627522 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Htra1 HtrA serine peptidase 1 ISO associated with Macular Degeneration; DNA:snp:cds:g.102C>T (rs1049331) (human) RGD PMID:21682878 RGD:7394697 NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD PMID:12149661, PMID:12425201, PMID:18619052 RGD:2312765 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ier3 immediate early response 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20713914 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Igf1 insulin-like growth factor 1 severity ISO
IEP
IAGP
mRNA:increased expression:aorta (rat)
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:19502719, PMID:22228705, PMID:16431135, PMID:8418983, PMID:15996002 RGD:1598427, RGD:12904968, RGD:1580474 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP protein:increased expression:aorta: RGD PMID:21854769 RGD:10046007 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 IEP mRNA, protein:decreased expression:liver, plasma RGD PMID:9396554 RGD:1626482 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:27659729, PMID:19246475 RGD:7495780 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il10 interleukin 10 IEP RGD PMID:19398662 RGD:2311047 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta IEP
ISO
IDA
mRNA, protein:increased expression:aorta, plasma
CTD Direct Evidence: marker/mechanism
associated with Obesity;protein:increased expression:plasma
CTD PMID:27292124, PMID:27659729, PMID:27847271, PMID:15894892, PMID:21173343, PMID:15990729 RGD:1626635, RGD:7175338, RGD:1626638 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility IDA
ISO
DNA:polymorphisms RGD PMID:11585563, PMID:11840488 RGD:1626668, RGD:1626667 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il6 interleukin 6 susceptibility ISO associated with end stage renal disease; DNA:polymorphisms:promoter: -174G>C (human)
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human)
CTD PMID:27292124, PMID:27659729, PMID:27847271, PMID:12846758, PMID:19043252 RGD:1580485, RGD:2307283 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor severity ISO Hypertension, Pregnancy-Induced;protein:increased expression:serum RGD PMID:11778537 RGD:1625432 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Il6st interleukin 6 signal transducer severity ISO Hypertension, Pregnancy-Induced;protein:increased expression:serum RGD PMID:11778537 RGD:1625432 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 ISO DNA:SNPs: :rs2276047,snp8,rs9886(human)
CTD Direct Evidence: marker/mechanism
CTD PMID:15220217, PMID:15220217 RGD:1626127 NCBI chr 1:166,898,177...166,912,524
Ensembl chr 1:166,899,894...166,912,524
JBrowse link
G Ins2 insulin 2 IDA
ISO
CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:9719048, PMID:18360027, PMID:9095092 RGD:6902896 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Itga9 integrin subunit alpha 9 susceptibility ISO DNA:SNP: :rs155524(human) RGD PMID:20479155 RGD:13602005 NCBI chr 8:127,271,029...127,576,709
Ensembl chr 8:127,271,289...127,572,988
JBrowse link
G Itgav integrin subunit alpha V IEP protein:increased expression:artery RGD PMID:16380536 RGD:1627642 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411
JBrowse link
G Itm2b integral membrane protein 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr15:55,254,703...55,277,713
Ensembl chr15:55,254,706...55,277,713
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:24039778, PMID:11358932 RGD:10047414 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 IEP mRNA:increased expression:heart RGD PMID:11358947 RGD:1627659 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 IEP mRNA:increased expression:aorta, arteries (rat) RGD PMID:11358947 RGD:1627659 NCBI chr 2:155,555,798...156,011,438
Ensembl chr 2:155,718,359...156,009,526
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:8899564, PMID:9445165, PMID:10807545, PMID:12402336, PMID:14661677, PMID:14760488, PMID:15051636, PMID:15599693, PMID:16132053, PMID:16266404, PMID:16487223, PMID:16823764, PMID:16887036, PMID:16922724, PMID:17016049, PMID:17161064, PMID:17210839, PMID:18426444, PMID:19305408, PMID:19695459, PMID:20823649, PMID:21244686, PMID:21712262, PMID:22100668, PMID:22378279, PMID:22581653, PMID:23861362, PMID:24033266, PMID:24400172, PMID:24499369, PMID:25737393, PMID:25741868, PMID:26132555, PMID:26743238, PMID:28003625, PMID:28492532, PMID:29625280, PMID:30311386, PMID:30847666, PMID:30910390, PMID:31308327, PMID:31376648 NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
JBrowse link
G Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 8:33,490,280...33,519,127
Ensembl chr 8:33,514,042...33,518,165
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 IEP RGD PMID:15964031 RGD:1598644 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 IDA RGD PMID:16051697 RGD:1581698 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 IDA
ISO
IEP
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:aorta, mesenteric artery
CTD PMID:17700361, PMID:14551242, PMID:16814121, PMID:16293791 RGD:1298970, RGD:10412046, RGD:1581718 NCBI chr10:18,910,586...18,922,856
Ensembl chr10:18,906,010...18,919,639
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 IAGP DNA:deletion:exon (rat) RGD PMID:16368876 RGD:1581602 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
G Kcnq1dfk potassium voltage-gated channel subfamily Q member 1;deafness Kyoto IAGP RGD PMID:16368876 RGD:1581602
G Kdr kinase insert domain receptor treatment IEP
ISO
DNA:polymorphism:cds:p.H472Q(human) RGD PMID:15838270, PMID:20630084 RGD:5684418, RGD:8552374 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Kl Klotho treatment IDA
IEP
ISO
mRNA,protein:decreased expression:kidney: RGD PMID:10892340, PMID:21051829, PMID:23225045 RGD:1581732, RGD:10403063, RGD:10403062 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
G Klk1 kallikrein 1 no_association
susceptibility
ISO
IEP
DNA:polymorphisms
CTD Direct Evidence: therapeutic
mRNA:decreased expression:kidney
RGD
CTD
PMID:14568997, PMID:15905889, PMID:15167446, PMID:15809361 RGD:1641795, RGD:1581751, RGD:1358144 NCBI chr 1:100,131,562...100,135,556
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Klk1b3 kallikrein 1-related peptidase B3 IAGP RGD PMID:15809361 RGD:1358144 NCBI chr 1:100,199,057...100,203,260
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Klk1c12 kallikrein 1-related peptidase C12 ISO DNA:polymorphisms RGD PMID:15905889, PMID:17272402 RGD:1641795, RGD:1641794 NCBI chr 1:99,298,965...99,303,048
Ensembl chr 1:99,299,011...99,303,048
JBrowse link
G Klkb1 kallikrein B1 ISO associated with Diabetes Mellitus, Type 1; protein:increased expression:plasma: RGD PMID:12716755 RGD:7327151 NCBI chr16:50,151,127...50,175,407
Ensembl chr16:50,152,008...50,175,458
JBrowse link
G Kng2 kininogen 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7027322 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO RGD PMID:15864294 RGD:1581757 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Kynu kynureninase IAGP RGD PMID:11924719 RGD:631322 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Lep leptin ISO
IDA
DNA:SNPs: :
CTD Direct Evidence: marker/mechanism
CTD PMID:12050272, PMID:16827954, PMID:25205467, PMID:27226618, PMID:19204185, PMID:20059648 RGD:5128788, RGD:5128597 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor ISO DNA:polymorphisms:exons
CTD Direct Evidence: marker/mechanism
CTD PMID:22949526, PMID:10999797 RGD:5129161 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Leprem2Mcwi leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin disease_progression IMP RGD PMID:27465994 RGD:12911217
G Lgals3 galectin 3 treatment IEP RGD PMID:23117656 RGD:9685203 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lhb luteinizing hormone subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:6350720 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Lipe lipase E, hormone sensitive type ISO gestational hypertension;DNA:polymorphism:promoter:-60C>G RGD PMID:17318300 RGD:1625026 NCBI chr 1:82,248,031...82,266,727
Ensembl chr 1:82,248,046...82,266,727
JBrowse link
G Lipg lipase G, endothelial type IDA RGD PMID:15914124 RGD:1581875 NCBI chr18:70,903,528...70,924,434
Ensembl chr18:70,901,710...70,924,708
JBrowse link
G Lox lysyl oxidase ISO
IDA
RGD PMID:8562290, PMID:24127 RGD:1581896, RGD:1581899 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Lpl lipoprotein lipase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705, PMID:16132104 RGD:1580535 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrp2 LDL receptor related protein 2 IDA protein:altered localization:apical plasma membrane RGD PMID:10919857 RGD:1641827 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551
JBrowse link
G Lta lymphotoxin alpha no_association ISO RGD PMID:15533732 RGD:1580415 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
JBrowse link
G Ltf lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:24587916 NCBI chr 8:119,290,416...119,313,261
Ensembl chr 8:119,290,416...119,313,261
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IEP RGD PMID:23499735 RGD:11561939 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IDA RGD PMID:15302844 RGD:1582315 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor IMP associated with Sleep Apnea Syndromes RGD PMID:21040717 RGD:5129169 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216
JBrowse link
G Mc2r melanocortin 2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11082157 NCBI chr18:64,166,959...64,178,729
Ensembl chr18:64,167,191...64,177,729
JBrowse link
G Mdh1 malate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr14:106,378,349...106,393,642
Ensembl chr14:106,378,942...106,393,670
JBrowse link
G Mfn2 mitofusin 2 treatment IEP protein:decreased expression:aorta (rat) RGD PMID:27847271, PMID:25464244 RGD:12910764, RGD:13204764 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mif macrophage migration inhibitory factor IDA RGD PMID:19799867 RGD:4890974 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mme membrane metallo-endopeptidase treatment IMP RGD PMID:12011651 RGD:13801039 NCBI chr 2:153,799,203...153,880,910
Ensembl chr 2:153,803,349...153,880,738
JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO protein:decreased expression:renal glomerulus (human) RGD PMID:15363819, PMID:19506087 RGD:1582532, RGD:2312464 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP
ISO
mRNA, protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
CTD PMID:18836702, PMID:17977875, PMID:16840178 RGD:2290351, RGD:1582612 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp7 matrix metallopeptidase 7 treatment IMP
IEP
RGD PMID:19398663, PMID:19398663 RGD:9685347, RGD:9685347 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mmp9 matrix metallopeptidase 9 susceptibility ISO
IEP
protein:decreased expression:internal mammary artery
CTD Direct Evidence: marker/mechanism
associated with Aneurysm, Dissecting;DNA:polymorphism:promoter:-1562C>T
CTD PMID:21051829, PMID:15363819, PMID:16780738, PMID:16840178, PMID:17977875 RGD:1582532, RGD:1642029, RGD:1582612, RGD:2290351 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mov10 Mov10 RISC complex RNA helicase susceptibility ISO DNA:SNP: :rs2932538(human) RGD PMID:24338417 RGD:13513987 NCBI chr 2:207,277,088...207,301,245
Ensembl chr 2:207,278,161...207,300,854
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:3814904 NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972
JBrowse link
G Msx2 msh homeobox 2 IEP RGD PMID:18270471 RGD:5132616 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527
JBrowse link
G Mtor mechanistic target of rapamycin kinase IDA
ISO
protein:increased serine phosphorylation:kidney
CTD Direct Evidence: marker/mechanism
CTD PMID:19289642, PMID:23323219 RGD:10041025 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mtpn myotrophin IEP
IDA
RGD PMID:12419325, PMID:12031792 RGD:632799, RGD:1581046 NCBI chr 4:63,012,009...63,039,422
Ensembl chr 4:63,012,011...63,039,422
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase ISO RGD PMID:15148588 RGD:1581050 NCBI chr17:66,210,444...66,295,014
Ensembl chr17:66,210,461...66,295,014
JBrowse link
G Mttp microsomal triglyceride transfer protein onset ISO DNA:polymorphism:promoter:-493G>T RGD PMID:16328015 RGD:1625485 NCBI chr 2:243,366,181...243,407,608
Ensembl chr 2:243,366,181...243,407,608
JBrowse link
G Mybph myosin binding protein H IAGP DNA:missense mutations:cds:p.I?T, p.R?K (rat) RGD PMID:23460292 RGD:12802369 NCBI chr13:51,034,228...51,041,903
Ensembl chr13:51,034,256...51,041,902
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27292124 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Myh7 myosin heavy chain 7 IEP protein:decreased expression:heart left ventricle, arteriole RGD PMID:9686760 RGD:9835388 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Myo6 myosin VI IDA protein:altered localization:renal proximal tubule, microvillus RGD PMID:16107581 RGD:2314963 NCBI chr 8:87,583,649...87,731,271
Ensembl chr 8:87,630,916...87,731,269
JBrowse link
G Myod1 myogenic differentiation 1 IEP mRNA:decreased expression:gastrocnemius RGD PMID:22076133 RGD:9686076 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16331104, PMID:17324946, PMID:19018797 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 IEP protein:increased expression:heart left ventricle RGD PMID:19307699 RGD:2314430 NCBI chr13:70,226,441...70,259,019
Ensembl chr13:70,226,647...70,257,576
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18524855, PMID:23348737 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 treatment IEP RGD PMID:23775684 RGD:10412717 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IEP RGD PMID:19246475 RGD:7495780 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Ngf nerve growth factor IEP RGD PMID:10797303 RGD:5144109 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngfr nerve growth factor receptor IAGP DNA,protein:missense mutation:CDS:c.28G>A, p.A10T (rat strains: SHR/Izm, SHRSP/Izm, WKHT) RGD PMID:8762194 RGD:5508800 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nisch nischarin IMP RGD PMID:12021582 RGD:1581128 NCBI chr16:7,254,372...7,290,670
Ensembl chr16:7,254,974...7,290,561
JBrowse link
G Nos1 nitric oxide synthase 1 treatment IEP
IDA
IMP
mRNA:decreased expression:bladder, penis RGD PMID:17574276, PMID:23201071, PMID:15913838, PMID:16093913, PMID:15775788, PMID:20494920 RGD:1642127, RGD:7257668, RGD:1581142, RGD:1581141, RGD:1581143, RGD:5132600 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos2 nitric oxide synthase 2 IEP
ISO
protein:increased expression, increased activity:kidney
CTD Direct Evidence: marker/mechanism
CTD PMID:18605955, PMID:25101153, PMID:27292124, PMID:15773227, PMID:11702222 RGD:1580264, RGD:1298023 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 treatment
no_association
IEP
IDA
ISO
associated with Pregnancy Complications
CTD Direct Evidence: marker/mechanism|therapeutic
DNA:duplication, snp:intron, cds:IVS4?-?+27, p.E298D (human)
DNA:snp:cds:p.E298D (human)
protein:decreased phosphorylation:brain
CTD PMID:11457755, PMID:12947532, PMID:16331104, PMID:19008412, PMID:19407804, PMID:18047920, PMID:29285068, PMID:29084084, PMID:10981549, PMID:11882615, PMID:9674630, PMID:20813549 RGD:2292113, RGD:13504683, RGD:13446414, RGD:1580278, RGD:1580271, RGD:1580282, RGD:4891993 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Notch2 notch receptor 2 ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:30311386 NCBI chr 2:200,187,184...200,320,403
Ensembl chr 2:200,187,179...200,320,215
JBrowse link
G Nox4 NADPH oxidase 4 IEP
IMP
ISO
protein:increased expression:aorta, vascular associated smooth muscle cell
CTD Direct Evidence: marker/mechanism
CTD PMID:27659729, PMID:27847271, PMID:18418428, PMID:26644237 RGD:2324669, RGD:11085830 NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194
JBrowse link
G Nppa natriuretic peptide A IEP
ISO
protein:increased expression:plasma:
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:2526952, PMID:7839143, PMID:8188982, PMID:9869009, PMID:12940879, PMID:19219041, PMID:24039778, PMID:20139323 RGD:7248593 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nppb natriuretic peptide B treatment
susceptibility
IEP
ISO
IDA
CTD Direct Evidence: marker/mechanism|therapeutic
DNA:repeats
CTD PMID:9194512, PMID:19219041, PMID:24039778, PMID:30310171, PMID:11897768, PMID:21403100, PMID:17554401 RGD:70484, RGD:5685657, RGD:1642191 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nppc natriuretic peptide C severity ISO associated with Pregnancy Complications;protein:increased expression:plasma RGD PMID:11775888, PMID:12452325 RGD:1642292, RGD:1580150 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636
JBrowse link
G Npr1 natriuretic peptide receptor 1 IAGP
ISO
DNA:repeat:promoter: (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:20881240, PMID:12511524 RGD:628585 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090
JBrowse link
G Npr3 natriuretic peptide receptor 3 ISO DNA:snp:promoter:g.-55C>A (human) RGD PMID:12872042 RGD:1580175 NCBI chr 2:61,883,946...61,950,291
Ensembl chr 2:61,888,950...61,949,926
JBrowse link
G Nptn neuroplastin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 8:63,379,062...63,445,694
Ensembl chr 8:63,379,087...63,445,686
JBrowse link
G Npy neuropeptide Y IMP
IEP
ISO
DNA:missense mutation:cds:p.L7P (human) RGD PMID:15699473, PMID:18835922, PMID:11689216 RGD:1357410, RGD:10448968, RGD:1580177 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Npy1r neuropeptide Y receptor Y1 IMP RGD PMID:15699473 RGD:1357410 NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IDA RGD PMID:21502369 RGD:11035215 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 IMP RGD PMID:25687237 RGD:10401852 NCBI chr 1:131,447,671...131,465,749
Ensembl chr 1:131,448,447...131,460,473
JBrowse link
G Nr2f2em1Mcwi nuclear receptor subfamily 2, group F, member 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP RGD PMID:25687237 RGD:10401852
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IMP
ISO
associated with fetal nutrition disorder
CTD Direct Evidence: marker/mechanism
CTD PMID:18434569, PMID:20659135, PMID:20674672, PMID:20659135 RGD:4892208, RGD:7174714 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nudt1 nudix hydrolase 1 IEP RGD PMID:17280880 RGD:10449166 NCBI chr12:16,391,578...16,398,771
Ensembl chr12:16,391,578...16,395,029
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 IEP
ISO
mRNA:increased expression:aorta (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:22352330, PMID:9494115 RGD:633385 NCBI chr 4:163,239,853...163,261,937
Ensembl chr 4:163,239,849...163,261,958
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IEP protein:increased expression:heart left ventricle (rat) RGD PMID:24388463 RGD:7800726 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19897708 NCBI chr12:38,981,903...38,995,570
Ensembl chr12:38,981,927...38,995,570
JBrowse link
G Oxsr1 oxidative stress responsive kinase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:22949526 NCBI chr 8:127,920,349...128,009,951
Ensembl chr 8:127,920,349...128,009,951
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IMP
ISO
IEP
CTD Direct Evidence: therapeutic
mRNA:decreased expression:paraventricular hypothalamic nucleus
CTD PMID:9334988, PMID:18562099, PMID:18562099, PMID:16157794 RGD:2304105, RGD:2304174 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G Oxtr oxytocin receptor IEP mRNA:decreased expression:brainstem RGD PMID:16157794 RGD:2304174 NCBI chr 4:144,399,326...144,417,598
Ensembl chr 4:144,403,358...144,416,116
JBrowse link
G Pappa1 pappalysin 1 ISO associated with Pregnancy Complications, Cardiovascular;protein:decreased expression:serum RGD PMID:12224070 RGD:1642331 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940
JBrowse link
G Pdgfb platelet derived growth factor subunit B IEP RGD PMID:8869081 RGD:10449484 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEP RGD PMID:1657776 RGD:11080972 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEP protein:increased tyrosine phosphorylation:glomerulus RGD PMID:12047046, PMID:1657776 RGD:2292214, RGD:11080972 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pgf placental growth factor ISO associated with Pregnancy Complications, Cardiovascular;mRNA:decreased expression:placenta RGD PMID:12808329 RGD:1642387 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEP
IMP
protein:decreased expression:ventricular myocyte (rat) RGD PMID:18300869, PMID:19015400 RGD:4108492, RGD:4108483 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:21810655 RGD:8693428 NCBI chr 8:21,669,236...21,680,615
Ensembl chr 8:21,669,236...21,680,615
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting ISO ClinVar Annotator: match by term: Hypertension
ClinVar Annotator: match by term: High blood pressure
ClinVar PMID:11115377, PMID:12482949, PMID:12842373, PMID:16430766, PMID:17574468, PMID:17582161, PMID:22333914, PMID:22508176, PMID:23064367, PMID:23431072, PMID:23760289, PMID:24694054, PMID:25333066, PMID:25741868, PMID:26467025, PMID:26632257, PMID:27499327, PMID:30311386 NCBI chr10:13,914,057...13,962,008
Ensembl chr10:13,915,214...13,962,008
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:25741868, PMID:30311386 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plcd1 phospholipase C, delta 1 IEP
IDA
protein:increased expression:aorta, arteriole, glomerulus
protein:increased activity:aorta
RGD PMID:17198910, PMID:1313006 RGD:2300421, RGD:2300423 NCBI chr 8:127,753,514...127,782,070
Ensembl chr 8:127,753,539...127,782,070
JBrowse link
G Plekha7em4Mcwi pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin IMP RGD PMID:25136115 RGD:11079199
G Plg plasminogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:6383834 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase no_association ISO
IEP
DNA:snps:5' utr:g.-390G>A, g.-184G>A rs876493 (human)
protein:decreased activity:adrenal gland (rat)
DNA:snp:5' utr:g.-390G>A (human)
RGD PMID:17645789, PMID:20378607, PMID:14553966 RGD:5130172, RGD:5130152, RGD:5130164 NCBI chr10:86,340,893...86,342,501
Ensembl chr10:86,340,940...86,342,858
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:76749, PMID:187612, PMID:216942, PMID:323586, PMID:1316127, PMID:1321011, PMID:1321309, PMID:1327015, PMID:1330390, PMID:1334993, PMID:1649024, PMID:1664305, PMID:2157753, PMID:2455169, PMID:2551692, PMID:2821097, PMID:2822310, PMID:2849322, PMID:2992854, PMID:3001556, PMID:3015460, PMID:4367732, PMID:6088243, PMID:6089027, PMID:6097376, PMID:6100240, PMID:6135010, PMID:6143199, PMID:6254450, PMID:6274577, PMID:6279500, PMID:6283272, PMID:8136112, PMID:8261660, PMID:8279378, PMID:8713685, PMID:8800598, PMID:9056691, PMID:9535146, PMID:10100081, PMID:10474778, PMID:10513829, PMID:10658937, PMID:11071300, PMID:11071304, PMID:11132610, PMID:11193135, PMID:11518849, PMID:11560123, PMID:11703388, PMID:12872045, PMID:12887135, PMID:15110907, PMID:15132301, PMID:15554453, PMID:16053986, PMID:16243970, PMID:16546835, PMID:16620303, PMID:17324744, PMID:17954371, PMID:17994356, PMID:18067589, PMID:18487447, PMID:19153526, PMID:19458537, PMID:20186125, PMID:20659135 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Postn periostin IEP associated with Renal Insufficiency, Chronic; protein:increased expression:left ventricle: RGD PMID:21712488 RGD:10041050 NCBI chr 2:143,656,820...143,688,087
Ensembl chr 2:143,656,793...143,688,087
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha treatment IEP
ISO
IMP
mRNA:increased expression:skeletal muscle
CTD Direct Evidence: marker/mechanism|therapeutic
CTD PMID:16054168, PMID:19834340, PMID:19763017, PMID:15967866 RGD:2313778, RGD:1580222 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IMP
ISO
IEP
IDA
CTD Direct Evidence: marker/mechanism|therapeutic
protein:decreased expression:rostral ventrolateral medulla (rat)
human gene in a mouse model
CTD PMID:15199296, PMID:19666838, PMID:27292124, PMID:18437150, PMID:20404217, PMID:18316027, PMID:12923396, PMID:15970297 RGD:2301888, RGD:7175297, RGD:2301864, RGD:1580690, RGD:1580684 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppbp pro-platelet basic protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:6192689, PMID:15513305 NCBI chr14:18,852,433...18,853,237
Ensembl chr14:18,851,954...18,853,315
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:25741868, PMID:28492532, PMID:30311386 NCBI chr 4:6,559,153...6,799,888
Ensembl chr 4:6,559,545...6,799,632
JBrowse link
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta ISO RGD PMID:11161799 RGD:619653 NCBI chr12:17,614,536...17,713,567
Ensembl chr12:17,614,632...17,712,373
JBrowse link
G Prkca protein kinase C, alpha IAGP RGD PMID:15792354 RGD:1581271 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prkcb protein kinase C, beta IDA RGD PMID:15804434 RGD:1625513 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prkcd protein kinase C, delta IEP
ISO
IAGP
protein:increased expression:heart, fibroblast
CTD Direct Evidence: marker/mechanism
CTD PMID:23973649, PMID:10756122, PMID:15792354 RGD:1642534, RGD:1581271 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Prkce protein kinase C, epsilon IAGP RGD PMID:15792354 RGD:1581271 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IEP mRNA, protein:splice variant, alternative form:basilar artery RGD PMID:14512447 RGD:7775067 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Prlhr prolactin releasing hormone receptor ISO DNA:SNP, missense mutation:promoter, cds:-62G>A, 914C>T (p.P305L) (human) RGD PMID:14691196 RGD:1641832 NCBI chr 1:281,754,472...281,756,159
Ensembl chr 1:281,754,724...281,756,159
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa ISO CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091
JBrowse link
G Ptch1 patched 1 ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:28492532, PMID:30311386 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873
JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:15646324 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptgds prostaglandin D2 synthase ISO protein:increased expression:serum, urine RGD PMID:11882588 RGD:1642584 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Ptgis prostaglandin I2 synthase ISO RGD PMID:12372404 RGD:1298040 NCBI chr 3:163,950,746...163,986,129 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IAGP
ISO
CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:14757778, PMID:15834289, PMID:20667508, PMID:22349312, PMID:15775781, PMID:16467505 RGD:1581285, RGD:1580671 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pth parathyroid hormone ISO protein:increased expression:serum (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:1930854, PMID:23460043 RGD:7242420 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Ptk2 protein tyrosine kinase 2 IAGP
IEP
protein:increased expression:aorta RGD PMID:12732587, PMID:21068519 RGD:729831, RGD:10041072 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta susceptibility ISO
IEP
DNA:polymorphism:promoter:-22A>G
protein:increased expression:aorta
RGD PMID:18075463, PMID:21068519 RGD:2292575, RGD:10041072 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 ISO CTD Direct Evidence: therapeutic CTD PMID:28899902 NCBI chr 3:164,665,462...164,711,936
Ensembl chr 3:164,665,532...164,711,848
JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J IAGP RGD PMID:15710778 RGD:1357414 NCBI chr 3:79,233,519...79,390,956
Ensembl chr 3:79,233,525...79,390,956
JBrowse link
G Ptpru protein tyrosine phosphatase, receptor type, U susceptibility ISO RGD PMID:11086029 RGD:1642652 NCBI chr 5:149,922,374...149,996,352
Ensembl chr 5:149,922,352...149,996,334
JBrowse link
G Qdpr quinoid dihydropteridine reductase IEP protein:decreased expression:aorta smooth muscle (rat) RGD PMID:19743417 RGD:5128580 NCBI chr14:70,164,682...70,178,284
Ensembl chr14:70,164,650...70,178,284
JBrowse link
G Rad51 RAD51 recombinase IDA RGD PMID:24239235 RGD:8693672 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Rag1 recombination activating 1 IMP RGD PMID:23364523 RGD:7207429 NCBI chr 3:91,206,394...91,217,491
Ensembl chr 3:91,206,394...91,217,491
JBrowse link
G Ralbp1 ralA binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23821548 NCBI chr 9:113,579,107...113,598,477
Ensembl chr 9:113,579,107...113,598,480
JBrowse link
G Ramp2 receptor activity modifying protein 2 susceptibility ISO
IEP
DNA:SNP:intron
associated with Pregnancy Complications
mRNA, protein:increased expression:heart myocardium, aorta
RGD PMID:15797661, PMID:11600589, PMID:16450076 RGD:1642679, RGD:1642682, RGD:1625300 NCBI chr10:89,166,170...89,168,962
Ensembl chr10:89,166,890...89,168,965
JBrowse link
G Rasgrp3 RAS guanyl releasing protein 3 ISO RGD PMID:19421330 RGD:2314812 NCBI chr 6:21,072,634...21,171,619
Ensembl chr 6:21,072,634...21,135,880
JBrowse link
G Reg3g regenerating family member 3 gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:27798352 NCBI chr 4:109,529,679...109,532,234
Ensembl chr 4:109,529,679...109,532,234
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:19018797, PMID:27659729, PMID:16840655 RGD:2298761 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ren renin IDA
ISO
CTD Direct Evidence: marker/mechanism
protein:decreased activity:plasma (mouse)
CTD PMID:45830, PMID:62162, PMID:998518, PMID:1071603, PMID:1149188, PMID:6381767, PMID:7721401, PMID:11501062, PMID:12414515, PMID:12600921, PMID:17537837, PMID:18679781, PMID:18847324, PMID:19770776, PMID:20429690, PMID:20811386, PMID:21393355, PMID:16467505, PMID:22493079, PMID:22681982, PMID:16138564 RGD:1580671, RGD:6892655, RGD:6784501, RGD:1580697 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Resp18 regulated endocrine-specific protein 18 IMP RGD PMID:29570433 RGD:14348960 NCBI chr 9:82,470,794...82,477,136
Ensembl chr 9:82,470,759...82,477,181
JBrowse link
G Resp18em2Mcwi regulated endocrine-specific protein 18; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:29570433 RGD:14348960
G Retn resistin ISO DNA:SNP:3' utr:*62A>G (human) RGD PMID:12629116 RGD:1624968 NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249
JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase IEP mRNA,protein:increased expression:heart RGD PMID:21357277 RGD:13442502 NCBI chr10:70,157,621...70,220,618
Ensembl chr10:70,157,621...70,220,582
JBrowse link
G Rgs2 regulator of G-protein signaling 2 ISO
IEP
CTD Direct Evidence: therapeutic CTD PMID:1798635, PMID:14608379, PMID:17986358 RGD:13524579, RGD:2289116 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094
JBrowse link
G Rgs4 regulator of G-protein signaling 4 treatment IEP RGD PMID:21825230 RGD:7207400 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108
JBrowse link
G Rgs5 regulator of G-protein signaling 5 treatment ISO
IEP
CTD Direct Evidence: therapeutic CTD PMID:1798635, PMID:21825230 RGD:7207400 NCBI chr13:87,966,820...88,002,831
Ensembl chr13:87,966,758...88,003,035
JBrowse link
G Rhoa ras homolog family member A IEP protein:altered localization:mesenteric artery RGD PMID:17620967 RGD:1642801 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO associated with Diabetes Mellitus Type 2; DNA:SNPs: : rs2296545,rs2576178 (human)
associated with kidney Failure,Chronic;DNA:SNPs: : rs2576178, rs10887800 (human)
RGD PMID:21964580, PMID:21178975, PMID:21617193 RGD:7327172, RGD:7327174, RGD:7327173 NCBI chr 1:251,828,285...252,101,963
Ensembl chr 1:251,828,290...252,100,759
JBrowse link
G Rnpep arginyl aminopeptidase IEP
IMP
protein:increased expression:adrenal gland, neurohypophysis RGD PMID:9660082, PMID:3001599 RGD:2325942, RGD:2325950 NCBI chr13:52,092,863...52,124,006
Ensembl chr13:52,092,859...52,111,363
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19289642 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G RT1-Ba RT1 class II, locus Ba ISO DNA:polymorphisms (human) RGD PMID:11798899 RGD:5147807 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721
JBrowse link
G S100b S100 calcium binding protein B ISO protein:increased expression:serum RGD PMID:21130083 RGD:5508770 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 disease_progression IAGP associated with SHRSP;mRNA,protein:increased expression, decreased expression:kidney (rat) RGD PMID:17938382 RGD:1643008 NCBI chr 2:218,654,406...218,658,761
Ensembl chr 2:218,654,554...218,658,761
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:30311386 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:11710892, PMID:19597050, PMID:20129283, PMID:22581653, PMID:24033266, PMID:24400668, PMID:24613995, PMID:24681144, PMID:25741868, PMID:28492532, PMID:29728395, PMID:30311386 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:11752024, PMID:23348737 NCBI chr 4:157,834,339...157,860,472
Ensembl chr 4:157,836,912...157,860,049
JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:15174897, PMID:15198480, PMID:19344079 NCBI chr 1:191,829,547...191,883,991
Ensembl chr 1:191,829,555...191,884,298
JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:15198480 NCBI chr 1:191,704,397...191,738,271
Ensembl chr 1:191,704,311...191,738,268
JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:24448499, PMID:25741868, PMID:28492532, PMID:30311386 NCBI chr 1:31,545,631...31,570,601
Ensembl chr 1:31,545,631...31,570,601
JBrowse link
G Selp selectin P ISO CTD Direct Evidence: marker/mechanism CTD PMID:15513305 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpina1 serpin family A member 1 ISO protein:increased expression:urine RGD PMID:10353322 RGD:1643147 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Serpine1 serpin family E member 1 treatment ISO
IEP
IDA
protein:increased expression:plasma (human)
mRNA:increased expression:kidney (SHRSP/A3N rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:21051829, PMID:22352330, PMID:8355419, PMID:11907153, PMID:16645728 RGD:8547753, RGD:28912746, RGD:11081003 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serpine2 serpin family E member 2 IEP mRNA, protein:increased expression:blood vessel RGD PMID:12524238 RGD:729767 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Serpinf2 serpin family F member 2 ISO RGD PMID:9361364 RGD:1625531 NCBI chr10:62,264,247...62,272,353
Ensembl chr10:62,264,788...62,273,119
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 no_association
susceptibility
ISO DNA:snps:exon, intron: (human) RGD PMID:15304560, PMID:16221215 RGD:1580969, RGD:1580968 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Sh2b3 SH2B adaptor protein 3 IMP RGD PMID:25776069 RGD:13442483 NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757
JBrowse link
G Sh2b3em1Mcwi SH2B adaptor protein 3; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP RGD PMID:25776069 RGD:13442483
G Slc12a2 solute carrier family 12 member 2 IEP
ISO
IDA
mRNA:increased expression:aorta
CTD Direct Evidence: marker/mechanism
CTD PMID:17259435, PMID:15020309, PMID:21814290 RGD:1580582, RGD:9587757 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261
JBrowse link
G Slc12a3 solute carrier family 12 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18480177 NCBI chr19:11,106,033...11,144,674
Ensembl chr19:11,106,033...11,144,641
JBrowse link
G Slc26a4 solute carrier family 26 member 4 ISO RGD PMID:17120771 RGD:7411553 NCBI chr 6:50,809,103...50,848,443
Ensembl chr 6:50,808,923...50,846,965
JBrowse link
G Slc2a1 solute carrier family 2 member 1 IEP protein:increased expression:renal glomerulus RGD PMID:12771048 RGD:12879474 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a3 solute carrier family 2 member 3 IEP protein:decreased expression:hippocampus, parietal cortex; protein:increased expression:hypothalamus, thalamus RGD PMID:7598707 RGD:1642812 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Slc34a1 solute carrier family 34 member 1 ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:16638441, PMID:25741868, PMID:30311386 NCBI chr17:9,747,766...9,762,739
Ensembl chr17:9,747,752...9,762,813
JBrowse link
G Slc4a4 solute carrier family 4 member 4 IEP protein:increased expression:kidney cortex RGD PMID:15340004 RGD:1600028 NCBI chr14:20,476,258...20,817,042
Ensembl chr14:20,479,323...20,920,286
JBrowse link
G Slc5a2 solute carrier family 5 member 2 IDA RGD PMID:14506074 RGD:1599050 NCBI chr 1:199,682,688...199,688,809
Ensembl chr 1:199,682,688...199,688,809
JBrowse link
G Slc6a18 solute carrier family 6 member 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15121838 NCBI chr 1:32,221,679...32,235,599
Ensembl chr 1:32,221,636...32,236,051
JBrowse link
G Slc6a19 solute carrier family 6 member 19 IEP mRNA:increased expression RGD PMID:17264310 RGD:1600036 NCBI chr 1:32,199,869...32,218,628
Ensembl chr 1:32,199,810...32,220,045
JBrowse link
G Slc6a2 solute carrier family 6 member 2 ISO DNA:polymorphism:1287G>A
CTD Direct Evidence: marker/mechanism
CTD PMID:22533655, PMID:17124432 RGD:1624279 NCBI chr19:15,391,682...15,431,274
Ensembl chr19:15,391,581...15,431,274
JBrowse link
G Slc6a3 solute carrier family 6 member 3 IEP protein:increased expression:caudate-putamen RGD PMID:9074541 RGD:1625656 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Slc8a1 solute carrier family 8 member A1 IEP
ISO
DNA:snps:intron:g.-23200T>C, g.-23181T>C (human)
DNA:SNP: :1784C>T
RGD PMID:16343576, PMID:15785003, PMID:15824464 RGD:1598724, RGD:1580732, RGD:1580586 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Slc9a3 solute carrier family 9 member A3 IDA RGD PMID:11880335, PMID:12372791 RGD:737665, RGD:727447 NCBI chr 1:31,731,652...31,777,144
Ensembl chr 1:31,734,327...31,777,070
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 IEP RGD PMID:15311100 RGD:1580741 NCBI chr10:103,713,045...103,730,145
Ensembl chr10:103,713,045...103,730,145
JBrowse link
G Slc9a3r2 SLC9A3 regulator 2 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:22228705, PMID:15311100 RGD:1580741 NCBI chr10:14,003,330...14,015,066
Ensembl chr10:14,003,320...14,013,870
JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO
IEP
associated with Hydronephrosis
CTD Direct Evidence: marker/mechanism|therapeutic
human gene in a rat model
mRNA:decreased expression:rostral ventrolateral medulla (rat)
CTD PMID:9024144, PMID:25101153, PMID:19403858, PMID:16716903, PMID:16864745, PMID:16716903, PMID:17198913 RGD:2312366, RGD:1580833, RGD:1581232, RGD:1580833, RGD:1600704 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 IDA
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:11834524, PMID:21593737, PMID:25101153, PMID:16716903 RGD:1580833 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 IDA
ISO
CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16864745, PMID:17023265, PMID:12600899, PMID:16864745 RGD:1580845, RGD:1581232 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sqstm1 sequestosome 1 IEP protein:decreased expression:brain RGD PMID:23499735 RGD:11561939 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IDA RGD PMID:16157790 RGD:1601372 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srf serum response factor IDA RGD PMID:16822834 RGD:1580749 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225
JBrowse link
G Sst somatostatin IEP protein:altered expression:stomach RGD PMID:17928643 RGD:2303191 NCBI chr11:80,358,172...80,359,449
Ensembl chr11:80,358,211...80,359,444
JBrowse link
G Stim1 stromal interaction molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19897708 NCBI chr 1:167,373,894...167,533,412
Ensembl chr 1:167,373,678...167,533,420
JBrowse link
G Stk11 serine/threonine kinase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19289642 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
JBrowse link
G Stk39 serine threonine kinase 39 ISO CTD Direct Evidence: therapeutic CTD PMID:22949526 NCBI chr 3:54,359,449...54,625,702
Ensembl chr 3:54,359,451...54,625,414
JBrowse link
G Sts steroid sulfatase IEP protein:increased expression:multiple organs RGD PMID:8539776 RGD:1601393 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750
JBrowse link
G Tac3 tachykinin precursor 3 IEP protein:increased expression:supraoptic nucleus, medulla oblongata RGD PMID:2478257 RGD:2305983 NCBI chr 7:71,023,976...71,030,582
Ensembl chr 7:71,023,976...71,030,582
JBrowse link
G Tacr1 tachykinin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21294877 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504
JBrowse link
G Tacr3 tachykinin receptor 3 IDA RGD PMID:2471579 RGD:2305984 NCBI chr 2:240,021,152...240,118,971
Ensembl chr 2:240,021,152...240,118,971
JBrowse link
G Tbxas1 thromboxane A synthase 1 IDA associated with hyperinsulinism RGD PMID:9370383, PMID:16192456 RGD:1601472, RGD:1601439 NCBI chr 4:66,624,181...66,846,745
Ensembl chr 4:66,670,618...66,846,805
JBrowse link
G Tf transferrin ISO protein:decreased expression RGD PMID:14974364 RGD:1601524 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEP
IAGP
ISO
protein:increased expression:vascular associated smooth muscle cell
mRNA:increased expression:kidney (SHRSP/A3N rat)
protein:increased expression:renal glomerulus
CTD Direct Evidence: marker/mechanism
CTD PMID:11682445, PMID:19018797, PMID:17364610, PMID:11907153, PMID:11682445, PMID:12771048, PMID:15118671 RGD:1601552, RGD:28912746, RGD:30296650, RGD:12879474, RGD:1331525 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb3 transforming growth factor, beta 3 no_association ISO DNA:polymorphism, SNPs RGD PMID:15924806 RGD:1625704 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Tgm2 transglutaminase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17898543 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
JBrowse link
G Th tyrosine hydroxylase susceptibility IEP
ISO
mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:intron:g.1090T>C rs2070762 (human)
CTD PMID:27659729, PMID:16650497, PMID:16636198 RGD:1601630, RGD:1601631 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Thbd thrombomodulin treatment IEP
ISO
associated with Experimental Diabetes Mellitus
protein:increased expression:plasma
protein:decreased expression:plasma
RGD PMID:14737039, PMID:16095049, PMID:17401180, PMID:12611420 RGD:1601646, RGD:5685017, RGD:1601636, RGD:1601652 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 ISO
IEP
protein:decreased expression:glomerulus
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:kidney
CTD PMID:21051829, PMID:19506087, PMID:17977875 RGD:2312464, RGD:2290351 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tjp2 tight junction protein 2 IEP protein:decreased expression:brain RGD PMID:17234953 RGD:1600163 NCBI chr 1:241,945,816...242,084,044
Ensembl chr 1:241,945,841...242,083,484
JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27292124 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tmem67 transmembrane protein 67 ISO ClinVar Annotator: match by term: High blood pressure ClinVar PMID:10508989, PMID:19466712, PMID:19508969, PMID:19540516, PMID:19574260, PMID:19778711, PMID:20232449, PMID:20607301, PMID:21068128, PMID:21866095, PMID:23559409, PMID:25729630, PMID:25741868, PMID:25920555, PMID:26035863, PMID:26092869, PMID:27491411, PMID:28492532, PMID:30311386 NCBI chr 5:25,666,138...25,721,056
Ensembl chr 5:25,666,137...25,721,072
JBrowse link
G Tnf tumor necrosis factor treatment IAGP
ISO
IMP
CTD Direct Evidence: marker/mechanism CTD PMID:18605955, PMID:27292124, PMID:27659729, PMID:27847271, PMID:9590569, PMID:16415373 RGD:1357163, RGD:1580207 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B severity ISO protein:increased expression:serum RGD PMID:22050177 RGD:7205512 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpm1 tropomyosin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
JBrowse link
G Trh thyrotropin releasing hormone IDA
ISO
protein:decreased expression:diencephalon
CTD Direct Evidence: marker/mechanism
CTD PMID:6350720, PMID:17227965 RGD:1600406 NCBI chr 4:124,110,716...124,113,242
Ensembl chr 4:124,110,716...124,113,242
JBrowse link
G Trhr thyrotropin releasing hormone receptor IDA RGD PMID:7554113 RGD:1580745 NCBI chr 7:83,113,641...83,153,520
Ensembl chr 7:83,113,672...83,153,519
JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17351372 NCBI chr 2:123,329,954...123,467,574
Ensembl chr 2:123,329,875...123,407,496
JBrowse link
G Trpc5 transient receptor potential cation channel, subfamily C, member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17351372 NCBI chr  X:115,624,670...115,908,248
Ensembl chr  X:115,627,653...115,908,693
JBrowse link
G Ucn urocortin ISO associated with Pregnancy Complications;protein:increased expression:plasma
CTD Direct Evidence: therapeutic
CTD PMID:20237592, PMID:16915033 RGD:1642775 NCBI chr 6:26,602,144...26,602,974
Ensembl chr 6:26,602,144...26,602,974
JBrowse link
G Ucn2 urocortin 2 ISO human protein in rat model RGD PMID:19204182 RGD:5508437 NCBI chr 8:117,727,216...117,728,765
Ensembl chr 8:117,727,877...117,728,764
JBrowse link
G Ucp1 uncoupling protein 1 ISO DNA:polymorphism: :-3826A>G (human) RGD PMID:17635070 RGD:2313626 NCBI chr19:24,456,976...24,464,808
Ensembl chr19:24,456,976...24,464,807
JBrowse link
G Ucp2 uncoupling protein 2 treatment ISO
IDA
CTD Direct Evidence: marker/mechanism CTD PMID:16685210, PMID:15106800, PMID:20404217 RGD:1580794, RGD:7175297 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Ucp3 uncoupling protein 3 IEP RGD PMID:10994754 RGD:1580795 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206
JBrowse link
G Umod uromodulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 1:189,186,027...189,199,939
Ensembl chr 1:189,186,026...189,199,376
JBrowse link
G Uts2 urotensin 2 ISO
IDA
protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
CTD PMID:16160878, PMID:15201550, PMID:14621188 RGD:1580808, RGD:1580812 NCBI chr 5:168,078,748...168,084,133
Ensembl chr 5:168,078,748...168,084,145
JBrowse link
G Uts2r urotensin 2 receptor IDA RGD PMID:14621188 RGD:1580812 NCBI chr10:110,364,291...110,365,451
Ensembl chr10:110,364,291...110,365,451
JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21115475 NCBI chr 2:212,247,061...212,585,818
Ensembl chr 2:212,247,451...212,585,818
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 disease_progression IEP
IAGP
ISO
mRNA:increased expression:multiple organs
associated with SHRSP;mRNA,protein:increased expression:kidney, membrane fraction (rat)
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type1; protein:increased expression:serum:
CTD PMID:11834524, PMID:19018797, PMID:19080338, PMID:17938382, PMID:20569722 RGD:2313107, RGD:1643008, RGD:7241235 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vdr vitamin D receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11335187 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vegfa vascular endothelial growth factor A treatment ISO associated with Prostatic Neoplasms RGD PMID:16164572, PMID:20630084 RGD:1580573, RGD:8552374 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO RGD PMID:12500216 RGD:1580371 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link
G Vwf von Willebrand factor treatment ISO
IEP
CTD Direct Evidence: marker/mechanism
associated with Experimental Diabetes Mellitus
CTD PMID:12149661, PMID:12425201, PMID:22352330, PMID:14737039 RGD:1601646 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22949526, PMID:16301342 RGD:1580829 NCBI chr 4:152,452,211...152,578,469
Ensembl chr 4:152,452,848...152,578,446
JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 no_association IAGP
ISO
CTD Direct Evidence: marker/mechanism CTD PMID:22949526, PMID:12642508, PMID:15110905 RGD:629611, RGD:1580830 NCBI chr10:89,181,139...89,198,213
Ensembl chr10:89,181,165...89,198,213
JBrowse link
G Xdh xanthine dehydrogenase treatment IDA
IEP
ISO
DNA:SNPs:exon, intron:47686C>T, 69901A>C, 67873A>C (p.N1109T) (human) RGD PMID:23746952, PMID:12826072, PMID:18712049, PMID:18728266 RGD:7247630, RGD:13210518, RGD:7247654, RGD:7247653 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta treatment IEP RGD PMID:22984478 RGD:9587480 NCBI chr 7:75,573,553...75,598,295
Ensembl chr 7:75,574,967...75,597,276
JBrowse link
angle-closure glaucoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E susceptibility ISO DNA:polymorphism:exon: RGD PMID:17706090 RGD:7771556 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Cat catalase severity ISO DNA:SNP:promoter:g.4760C>T(rs1001179)(human) RGD PMID:23961996 RGD:9068947 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Chat choline O-acetyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27064256 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Col11a1 collagen type XI alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:22922875, PMID:27064256 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain ISO ClinVar Annotator: match by term: GLAUCOMA, PRIMARY CLOSED-ANGLE ClinVar PMID:30007336 NCBI chr20:12,225,202...12,332,858
Ensembl chr20:12,225,202...12,332,858
JBrowse link
G Edn1 endothelin 1 ISO protein:increased expression:plasma (human) RGD PMID:21946544 RGD:8661736 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Epdr1 ependymin related 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27064256 NCBI chr17:47,397,558...47,422,183
Ensembl chr17:47,397,558...47,422,182
JBrowse link
G Fermt2 fermitin family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27064256 NCBI chr15:19,807,806...19,876,557
Ensembl chr15:19,807,808...19,876,408
JBrowse link
G Glis3 GLIS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27064256 NCBI chr 1:246,380,816...246,564,385
Ensembl chr 1:246,380,889...246,785,360
JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion, haplotype:cds (human) RGD PMID:18334963 RGD:7488955 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Hgf hepatocyte growth factor susceptibility ISO DNA:SNPs,haplotype::rs5745718,rs1742817(human) RGD PMID:23585864 RGD:8548548 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Loxl1 lysyl oxidase-like 1 no_association ISO DNA:SNPs: :rs1048661, rs2165241, rs3825942 (human) RGD PMID:18223248 RGD:7394723 NCBI chr 8:63,067,757...63,092,124
Ensembl chr 8:63,067,300...63,092,009
JBrowse link
G Mmp9 matrix metallopeptidase 9 no_association ISO DNA:SNP: :rs2664538 (human)
DNA:SNP:promoter:-1562C>T (human)
DNA:SNP: :c.836A>G (rs17576) (human)
DNA:SNPs: :rs17576, rs3918249 (human)
RGD PMID:17110919, PMID:23441116, PMID:23441116, PMID:21655354 RGD:8547816, RGD:8549724, RGD:8549724, RGD:8547830 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO DNA:SNPs: :677C>T,1298A>C(human) RGD PMID:19936026 RGD:7387250 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming ISO associated with Cataract;protein:decreased expression:tear RGD PMID:21139981 RGD:7364742 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:duplication:intron:IVS4?-?+27 (human)
DNA:snps:introns:g.IVS5+1182G>A, g.IVS25+11C>A (rs3793342, rs7830) (human)
RGD PMID:20069064, PMID:23422825 RGD:7771573, RGD:7775046 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Plekha7 pleckstrin homology domain containing A7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22922875, PMID:27064256 NCBI chr 1:185,427,600...185,493,985
Ensembl chr 1:185,356,975...185,538,694
JBrowse link
G Prss56 serine protease 56 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21532570 NCBI chr 9:94,278,981...94,284,111
Ensembl chr 9:94,279,155...94,283,919
JBrowse link
G Tfap2b transcription factor AP-2 beta ISS MouseDO NCBI chr 9:25,410,669...25,440,568
Ensembl chr 9:25,410,669...25,440,411
JBrowse link
anterior segment dysgenesis 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxc1 forkhead box C1 ISO ClinVar Annotator: match by term: Anterior segment dysgenesis 3
ClinVar Annotator: match by term: Iridogoniodysgenesis type1
ClinVar Annotator: match by OMIM:601631
OMIM
ClinVar
PMID:9620769, PMID:9792859, PMID:11007653, PMID:11170889, PMID:12036988, PMID:19668217, PMID:19793056, PMID:25741868, PMID:28492532 NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484
JBrowse link
anterior segment dysgenesis 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pitx2 paired-like homeodomain 2 ISO ClinVar Annotator: match by term: Anterior segment dysgenesis 4
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: ANTERIOR SEGMENT DYSGENESIS 4
ClinVar Annotator: match by term: Iridogoniodysgenesis, dominant type
ClinVar Annotator: match by OMIM:137600
OMIM
ClinVar
CTD
PMID:7581385, PMID:8942889, PMID:9437321, PMID:9618168, PMID:10502778, PMID:25741868, PMID:28492532, PMID:32499604 NCBI chr 2:233,602,732...233,621,059
Ensembl chr 2:233,602,732...233,621,129
JBrowse link
buphthalmos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 susceptibility ISO ClinVar Annotator: match by term: Glaucoma 3, primary congenital, A
ClinVar Annotator: match by term: Glaucoma, congenital
ClinVar Annotator: match by term: Glaucoma, primary open angle, juvenile-onset
ClinVar Annotator: match by term: Congenital glaucoma
ClinVar Annotator: match by OMIM:231300
DNA:missense mutation:cds:p.A388T (human)
DNA:missense mutation, deletion:exon:p.R390H, g.4633delC (human)
DNA:duplication:exon:g.1546-1555dupTCATGCCACC (human)
DNA:missense mutations:exons:p.G61E, p.R368H, p.D374N (human)
DNA:missense mutations:exons:p.G61E, p.R469W, p.R523K (human)
DNA:deletion, snp:exons:g.4339delG, p.G61E (human)
DNA:snp:cds:p.E387K (human)
DNA:polymorphisms:multiple (human)
OMIM
ClinVar
PMID:9097971, PMID:9463332, PMID:9497261, PMID:10227395, PMID:10426814, PMID:10655546, PMID:10739169, PMID:10910054, PMID:11403040, PMID:11527932, PMID:11558822, PMID:11774072, PMID:11854439, PMID:11980847, PMID:12036985, PMID:12372064, PMID:14507861, PMID:15037581, PMID:15255109, PMID:15342693, PMID:16384942, PMID:16688110, PMID:16735991, PMID:16735994, PMID:16862072, PMID:17164573, PMID:17363580, PMID:17563717, PMID:17591938, PMID:17718864, PMID:17893647, PMID:18227148, PMID:18414103, PMID:18470941, PMID:18537981, PMID:18622259, PMID:18852424, PMID:19234632, PMID:19247456, PMID:19536304, PMID:19597567, PMID:19643970, PMID:19744731, PMID:19793111, PMID:19807744, PMID:20151268, PMID:20198978, PMID:20664688, PMID:21081970, PMID:21168818, PMID:21600657, PMID:21815720, PMID:21850185, PMID:21854771, PMID:22004014, PMID:22128238, PMID:22942166, PMID:23028769, PMID:23218183, PMID:23218701, PMID:23922489, PMID:24033266, PMID:24281366, PMID:24940937, PMID:25091052, PMID:25109919, PMID:25527694, PMID:25646030, PMID:25741868, PMID:25950505, PMID:25978063, PMID:26550974, PMID:27060699, PMID:27243976, PMID:27272408, PMID:27408750, PMID:27508083, PMID:27535533, PMID:27777502, PMID:27820421, PMID:28192799, PMID:28384041, PMID:28448622, PMID:28492532, PMID:28620713, PMID:29556725, PMID:30311386, PMID:32499604, PMID:94927261, PMID:16490498, PMID:19247456, PMID:12567107, PMID:19597567, PMID:19593207, PMID:20664688, PMID:10227395, PMID:23922489, PMID:12624268 RGD:7800719, RGD:7800711, RGD:7800707, RGD:7800689, RGD:7800688, RGD:7800680, RGD:7800670, RGD:7800657, RGD:734869 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Foxc1 forkhead box C1 ISS
ISO
OMIM:231300
ClinVar Annotator: match by term: Congenital glaucoma
MouseDO
ClinVar
NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484
JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 ISO ClinVar Annotator: match by term: Glaucoma, congenital
ClinVar Annotator: match by term: Congenital glaucoma
ClinVar PMID:19656777, PMID:24033266 NCBI chr 6:108,500,114...108,596,653
Ensembl chr 6:108,500,112...108,596,569
JBrowse link
G Myoc myocilin ISO ClinVar Annotator: match by term: Glaucoma 3, primary congenital, a, digenic ClinVar PMID:12447164, PMID:15025728, PMID:15723004, PMID:15733270, PMID:16288197, PMID:17563717, PMID:22194650, PMID:22736945 NCBI chr13:80,517,531...80,527,928
Ensembl chr13:80,517,536...80,527,928
JBrowse link
G Rmdn2 regulator of microtubule dynamics 2 ISO ClinVar Annotator: match by term: Glaucoma 3, primary congenital, A ClinVar NCBI chr 6:2,215,062...2,292,288
Ensembl chr 6:2,216,623...2,280,777
JBrowse link
G Tyr tyrosinase ISS OMIM:231300 MouseDO NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
Charcot-Marie-Tooth disease type 4B2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sbf2 SET binding factor 2 ISO ClinVar Annotator: match by term: Charcot-Marie-Tooth disease, type 4B2
ClinVar Annotator: match by term: Charcot-Marie-Tooth disease type 4B2 with early-onset glaucoma
ClinVar Annotator: match by OMIM:604563
ClinVar Annotator: match by null
OMIM
ClinVar
PMID:9521281, PMID:10932274, PMID:12554688, PMID:12687498, PMID:15304601, PMID:15477569, PMID:25025039, PMID:25741868, PMID:26392352, PMID:26467025, PMID:27582484, PMID:28492532 NCBI chr 1:174,948,361...175,420,161
Ensembl chr 1:174,948,913...175,420,160
JBrowse link
Diastolic Hypertension, Resistance to term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnip1 potassium voltage-gated channel interacting protein 1 ISO ClinVar Annotator: match by null ClinVar PMID:15057310, PMID:16155733 NCBI chr10:18,558,128...18,942,677
Ensembl chr10:18,558,128...18,942,540
JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 ISO ClinVar Annotator: match by OMIM:608622 OMIM
ClinVar
PMID:15057310, PMID:16155733 NCBI chr10:18,910,586...18,922,856
Ensembl chr10:18,906,010...18,919,639
JBrowse link
Dursun Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pc3 glucose 6 phosphatase catalytic subunit 3 ISO ClinVar Annotator: match by term: Dursun syndrome ClinVar PMID:19011569, PMID:20799326, PMID:25741868 NCBI chr10:90,134,193...90,138,425
Ensembl chr10:90,134,193...90,138,425
JBrowse link
eclampsia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 treatment IDA RGD PMID:27106269 RGD:11062145 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
essential hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsm3 acyl-CoA synthetase medium-chain family member 3 no_association ISO RGD PMID:11592044 RGD:1579978 NCBI chr 1:189,514,504...189,541,233
Ensembl chr 1:189,514,553...189,541,224
JBrowse link
G Add1 adducin 1 ISO ClinVar Annotator: match by term: Hypertension, salt-sensitive essential, susceptibility to OMIM
ClinVar
PMID:9149697, PMID:9607177, PMID:10024330, PMID:21692745, PMID:22992668 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496
JBrowse link
G Agt angiotensinogen ISO ClinVar Annotator: match by term: Hypertension, essential, susceptibility to OMIM
ClinVar
PMID:7649545, PMID:7883995, PMID:8348146, PMID:8513325, PMID:8518804, PMID:9120024, PMID:9259580, PMID:9421481, PMID:9831339, PMID:9894356, PMID:13937884, PMID:15077204, PMID:16059745, PMID:17047091, PMID:20978123, PMID:25741868 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a treatment ISO ClinVar Annotator: match by term: Hypertension, essential, susceptibility to OMIM
ClinVar
PMID:8021009, PMID:9084931, PMID:15042429, PMID:17668390, PMID:18604484 RGD:10047396 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 ISO OMIM NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 susceptibility ISO DNA:polymorphism:exon:p.A724A (c.2171G>A)(human) RGD PMID:20687374 RGD:13507310 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 ISO protein:increased expression:plasma (human) RGD PMID:14654753 RGD:13800915 NCBI chr11:24,286,806...24,294,419
Ensembl chr11:24,286,787...24,294,179
JBrowse link
G Cat catalase ISO RGD PMID:15735318 RGD:1581147 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 ISO ClinVar Annotator: match by term: Hypertension, salt-sensitive essential, susceptibility to OMIM
ClinVar
PMID:11279519, PMID:11740341, PMID:12065767, PMID:12754175, PMID:15492926 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Ece1 endothelin converting enzyme 1 ISO OMIM NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G Eln elastin ISS OMIM:145500 | OMIM:603918 | OMIM:604329 | OMIM:607329 | OMIM:608742 | OMIM:610261 | OMIM:610262 | OMIM:610948 | OMIM:611014 MouseDO NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Gata5 GATA binding protein 5 ISS OMIM:145500 | OMIM:603918 | OMIM:604329 | OMIM:607329 | OMIM:608742 | OMIM:610261 | OMIM:610262 | OMIM:610948 | OMIM:611014 MouseDO NCBI chr 3:175,701,278...175,709,465
Ensembl chr 3:175,701,280...175,709,465
JBrowse link
G Gnb3 G protein subunit beta 3 ISO OMIM NCBI chr 4:157,352,558...157,359,237
Ensembl chr 4:157,352,372...157,358,262
JBrowse link
G Grk4 G protein-coupled receptor kinase 4 susceptibility ISO DNA:SNP,haplotypes:cds: RGD PMID:15097232, PMID:15097232 RGD:1598505, RGD:1598505 NCBI chr14:81,261,708...81,339,516
Ensembl chr14:81,265,672...81,339,526
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO protein:increased expression:urine: RGD PMID:22923545 RGD:7245500 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Lcn2 lipocalin 2 ISO protein:increased expression:urine: RGD PMID:22923545 RGD:7245500 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Nos3 nitric oxide synthase 3 ISO DNA:repeats:intron:IVS13+?-?dupCA (human)
DNA:snp:cds:p.E298D (human)
OMIM PMID:9084930, PMID:11394896 RGD:1580277, RGD:1580280 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nppb natriuretic peptide B ISO protein:increased expression:plasma: RGD PMID:9350073 RGD:7246914 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Npr2 natriuretic peptide receptor 2 ISO DNA:repeat:intron:IVS2+150(GT)10-11 (human) RGD PMID:10082481 RGD:1580772 NCBI chr 5:59,128,186...59,147,321
Ensembl chr 5:59,128,315...59,147,255
JBrowse link
G Ptgis prostaglandin I2 synthase ISO ClinVar Annotator: match by OMIM:145500 OMIM
ClinVar
PMID:12372404 NCBI chr 3:163,950,746...163,986,129 JBrowse link
G Rarres2 retinoic acid receptor responder 2 ISO protein:increased expression:serum: RGD PMID:24047472 RGD:15036820 NCBI chr 4:78,205,809...78,208,956
Ensembl chr 4:78,205,812...78,208,767
JBrowse link
G Rgs5 regulator of G-protein signaling 5 ISO OMIM NCBI chr13:87,966,820...88,002,831
Ensembl chr13:87,966,758...88,003,035
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO DNA:SNPs: :rs2576178, rs2296545,rs2114406 (human) RGD PMID:17216203 RGD:7327177 NCBI chr 1:251,828,285...252,101,963
Ensembl chr 1:251,828,290...252,100,759
JBrowse link
G Slc12a3 solute carrier family 12 member 3 severity ISO DNA:missense mutation:cds:p.R904Q (human)
DNA:snp:intron:g.1784C>T (human)
RGD PMID:15480096, PMID:15824464 RGD:1580589, RGD:1580586 NCBI chr19:11,106,033...11,144,674
Ensembl chr19:11,106,033...11,144,641
JBrowse link
G Umod uromodulin ISO ClinVar Annotator: match by term: Essential hypertension ClinVar NCBI chr 1:189,186,027...189,199,939
Ensembl chr 1:189,186,026...189,199,376
JBrowse link
exfoliation syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28553957 NCBI chr20:4,369,399...4,378,272
Ensembl chr20:4,369,178...4,378,269
JBrowse link
G Apoe apolipoprotein E susceptibility ISO DNA:polymorphism:exon: RGD PMID:15939044 RGD:7771555 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25706626 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cav1 caveolin 1 no_association ISO DNA:SNP:promoter:rs4236601 (human) RGD PMID:20835238 RGD:8661783 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Clu clusterin no_association ISO DNA:SNPs, haplotype: :multiple
DNA:SNP:intron:rs2279590 (human)
RGD PMID:18806885, PMID:25057782, PMID:19182256, PMID:19182256, PMID:16639006 RGD:8699505, RGD:9068391, RGD:8887372, RGD:8887372, RGD:8699516 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Edn1 endothelin 1 ISO associated with Cataract;protein:increased expression:aqueous humor (human) RGD PMID:15031170 RGD:8661674 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Eln elastin ISO RGD PMID:7777294 RGD:9585736 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility
no_association
ISO DNA:deletion, haplotype:cds (human)
DNA:deletion:cds (human)
RGD PMID:18334963, PMID:16020292 RGD:7488955, RGD:7495792 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility
no_association
ISO DNA:deletion:cds (human)
mRNA:decreased expression:ciliary processes, iris (human)
RGD PMID:21151336, PMID:18055805, PMID:16020292 RGD:7794822, RGD:7794853, RGD:7495792 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Loxl1 lysyl oxidase-like 1 susceptibility
no_association
ISO DNA:SNP: :p.R141L (rs1048661) (human)
ClinVar Annotator: match by term: Exfoliation syndrome, susceptibility to
CTD Direct Evidence: marker/mechanism
DNA:CNVs
DNA:SNPs:exon:p.R141L, p.G153D (human)
DNA:SNP, haplotypes:promoter:multiple
DNA:SNP:exon:rs1048661, rs3825942 (human)
DNA:SNP, haplotypes: :rs1048661, rs3825942 (human)
DNA:SNP: :multiple
ClinVar
OMIM
CTD
PMID:17690259, PMID:18037624, PMID:19343041, PMID:25706626, PMID:28553957, PMID:23378724, PMID:19029039, PMID:23288989, PMID:21320968, PMID:21212179, PMID:21740868, PMID:22605916, PMID:19503743, PMID:19373106 RGD:7387325, RGD:7394726, RGD:7387333, RGD:7387332, RGD:7387331, RGD:7387329, RGD:7387328, RGD:7387327, RGD:7387326 NCBI chr 8:63,067,757...63,092,124
Ensembl chr 8:63,067,300...63,092,009
JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 ISO ClinVar Annotator: match by term: Exfoliation Syndrome
ClinVar Annotator: match by term: Pseudoexfoliation glaucoma
ClinVar PMID:23401661, PMID:28492532 NCBI chr 6:108,500,114...108,596,653
Ensembl chr 6:108,500,112...108,596,569
JBrowse link
G Lyst lysosomal trafficking regulator ISS OMIM:177650 MouseDO NCBI chr17:90,323,055...90,522,091 JBrowse link
G Mmp1 matrix metallopeptidase 1 no_association ISO DNA:insertion:promoter:g.-1607insG rs1799750 (human) RGD PMID:20808730 RGD:8549725 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp9 matrix metallopeptidase 9 no_association ISO DNA:insertion: :p.Q279R (rs17576) (human) RGD PMID:20808730 RGD:8549725 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Optn optineurin no_association ISO DNA:polymorphism: :p.M98K (human) RGD PMID:16020311 RGD:6480509 NCBI chr17:77,167,700...77,218,374
Ensembl chr17:77,167,740...77,218,389
JBrowse link
G Pomp proteasome maturation protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28553957 NCBI chr12:8,746,948...8,759,433
Ensembl chr12:8,746,855...8,759,599
JBrowse link
G Pon1 paraoxonase 1 ISO protein:decreased expression:serum (human) RGD PMID:19628957 RGD:8547685 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Rbms3 RNA binding motif, single stranded interacting protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28553957 NCBI chr 8:124,833,804...125,645,895
Ensembl chr 8:124,661,839...125,645,898
JBrowse link
G Sod2 superoxide dismutase 2 ISO associated with cataract;mRNA:increased expression:lens epithelium:
associated with glaucoma,primary open angle; mRNA:increased expression: ciliary body, iris:
RGD PMID:23805041, PMID:18055805 RGD:8158048, RGD:7794853 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tlcd5 TLC domain containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28553957 NCBI chr 8:47,399,122...47,404,018
Ensembl chr 8:47,396,741...47,404,010
JBrowse link
G Tlr4 toll-like receptor 4 susceptibility ISO DNA:haplotype:: RGD PMID:22831837 RGD:7794768 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
glaucoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin I converting enzyme 2 treatment IDA RGD PMID:23702784 RGD:9685447 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Anxa3 annexin A3 IEP mRNA:increased expression:retina RGD PMID:18055803 RGD:2289160 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Apoa4 apolipoprotein A4 ISO Primary Congenital Glaucoma; protein:increased expression:aqueous humor (human) RGD PMID:21078314 RGD:5685641 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apoe apolipoprotein E ISO GAD PMID:15118671 RGD:1331525 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Atf2 activating transcription factor 2 IEP RGD PMID:17586494 RGD:10047416 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Bad BCL2-associated agonist of cell death IEP protein:decreased serine phosphorylation:retina RGD PMID:16103353 RGD:2292690 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator IEP mRNA:increased expression:optic nerve, retina RGD PMID:24357921 RGD:10054098 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator IEP mRNA:decreased expression:optic nerve, retina RGD PMID:24357921 RGD:10054098 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor treatment ISO
IDA
IEP
protein:decreased expression:eye: RGD PMID:19422885, PMID:21498611, PMID:10711692 RGD:8655601, RGD:8655886, RGD:8655608 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 IEP protein:increased expression:eye RGD PMID:22476098 RGD:6483048 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bex3 brain expressed X-linked 3 IEP mRNA:decreased expression:retina RGD PMID:19682984 RGD:9743977 NCBI chr  X:106,823,442...106,825,016
Ensembl chr  X:106,823,491...106,825,014
JBrowse link
G Ccnd2 cyclin D2 IEP mRNA:increased expression:retina RGD PMID:18055803 RGD:2289160 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 ISO RGD PMID:16159632 RGD:8549757 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B IEP mRNA, protein:decreased expression:retina, Muller cell RGD PMID:16707124 RGD:2293623 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21532571 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21532571 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cfh complement factor H ISO protein:decreased expression:retina: RGD PMID:20484586 RGD:7364950 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
JBrowse link
G Cntf ciliary neurotrophic factor IDA
ISO
RGD PMID:14725620, PMID:19060281 RGD:1626115, RGD:8655853 NCBI chr 1:229,599,009...229,601,032
Ensembl chr 1:229,599,009...229,601,032
JBrowse link
G Col2a1 collagen type II alpha 1 chain ISO ClinVar Annotator: match by term: Glaucoma ClinVar PMID:11007540, PMID:20179744, PMID:22496037, PMID:22522174, PMID:26747767, PMID:27390512, PMID:28492532, PMID:29453956, PMID:30181686, PMID:30311386 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Crb1 crumbs cell polarity complex component 1 ISO ClinVar Annotator: match by term: Glaucoma ClinVar PMID:30311386 NCBI chr13:56,270,519...56,462,893
Ensembl chr13:56,270,781...56,462,834
JBrowse link
G Crebbp CREB binding protein ISO ClinVar Annotator: match by term: Glaucoma ClinVar PMID:25741868, PMID:30311386 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:24989686 RGD:9384823 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cyp4v3 cytochrome P450, family 4, subfamily v, polypeptide 3 ISO ClinVar Annotator: match by term: Glaucoma ClinVar PMID:15042513, PMID:28492532, PMID:30311386 NCBI chr16:50,111,803...50,136,741
Ensembl chr16:50,111,306...50,136,727
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 ISO associated with Exfoliation Syndrome; RGD PMID:20107165 RGD:10401222 NCBI chr 7:11,401,501...11,406,771
Ensembl chr 7:11,401,501...11,406,771
JBrowse link
G Epo erythropoietin ISO
IEP
protein:increased expression:retina: RGD PMID:19741249, PMID:17554621, PMID:17554621 RGD:10401071, RGD:11041649, RGD:11041649 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Epor erythropoietin receptor IEP protein:increased expression:retina: RGD PMID:17554621 RGD:11041649 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G Fas Fas cell surface death receptor ISO protein:increased expression:optic nerve head, axon (human) RGD PMID:19043361 RGD:8662440 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Foxc1 forkhead box C1 ISO associated with Axenfeld-Rieger Syndrome;DNA:mutation:cds:p.Q120X(human) RGD PMID:18498376 RGD:12904045 NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484
JBrowse link
G Ivd isovaleryl-CoA dehydrogenase ISO ClinVar Annotator: match by term: Glaucoma ClinVar PMID:28492532, PMID:30311386 NCBI chr 3:110,669,355...110,689,789
Ensembl chr 3:110,669,312...110,690,173
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 ISS MouseDO NCBI chr 3:101,051,960...101,152,119
Ensembl chr 3:101,051,955...101,152,119
JBrowse link
G Lingo1 leucine rich repeat and Ig domain containing 1 treatment ISO RGD PMID:19422885 RGD:8655601 NCBI chr 8:61,272,125...61,455,480
Ensembl chr 8:61,274,017...61,290,240
JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19361779, PMID:27149523 NCBI chr 6:108,500,114...108,596,653
Ensembl chr 6:108,500,112...108,596,569
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IEP protein:increased expression:optic nerve RGD PMID:24136224 RGD:13782046 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor treatment IMP RGD PMID:23702784 RGD:9685447 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:16185954 RGD:8547817 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming ISO protein:increased expression:conjunctival epithelial cell RGD PMID:16809382 RGD:7364743 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Mylk myosin light chain kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20375339 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158
JBrowse link
G Myoc myocilin TAS
ISO
ClinVar Annotator: match by term: Glaucoma
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:9535666, PMID:9772276, PMID:9804137, PMID:10196380, PMID:10330365, PMID:10545602, PMID:10798654, PMID:10980537, PMID:11004290, PMID:11133859, PMID:11152659, PMID:11281418, PMID:11298682, PMID:11803488, PMID:12189160, PMID:12356829, PMID:12442283, PMID:12872267, PMID:14688426, PMID:14764620, PMID:14767915, PMID:15790895, PMID:16148883, PMID:16466712, PMID:16636654, PMID:17438518, PMID:17893664, PMID:18776955, PMID:19145250, PMID:21552496, PMID:21850185, PMID:22736945, PMID:22933836, PMID:23029558, PMID:23922489, PMID:24033266, PMID:25741868, PMID:27485216, PMID:28492532, PMID:30389787, PMID:31959993, PMID:10833334 RGD:633384 NCBI chr13:80,517,531...80,527,928
Ensembl chr13:80,517,536...80,527,928
JBrowse link
G Nefh neurofilament heavy IEP protein:decreased expression:optic nerve: RGD PMID:28498493 RGD:27226819 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Ngf nerve growth factor IEP protein:decreased expression:cerebrospinal fluid RGD PMID:18938194 RGD:2303806 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngfr nerve growth factor receptor IDA RGD PMID:20943663 RGD:5508695 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 treatment IDA RGD PMID:24136224 RGD:13782046 NCBI chr 8:106,317,038...106,429,535
Ensembl chr 8:106,317,124...106,429,522
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 IEP
IDA
mRNA,protein:decreased expression:eye RGD PMID:18817846, PMID:20943663 RGD:5684379, RGD:5508695 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IDA
IEP
protein:increased expression:eye: RGD PMID:20357199, PMID:10711692 RGD:5684908, RGD:8655608 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase treatment ISO RGD PMID:18936150, PMID:20664796 RGD:7800698, RGD:7800720 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Optn optineurin susceptibility ISO DNA:SNP:intron: RGD PMID:16148883 RGD:7771548 NCBI chr17:77,167,700...77,218,374
Ensembl chr17:77,167,740...77,218,389
JBrowse link
G Pccb propionyl-CoA carboxylase subunit beta ISO ClinVar Annotator: match by term: Glaucoma ClinVar PMID:28492532, PMID:30311386 NCBI chr 8:109,368,887...109,418,871
Ensembl chr 8:109,368,624...109,418,872
JBrowse link
G Pitx2 paired-like homeodomain 2 ISS MouseDO NCBI chr 2:233,602,732...233,621,059
Ensembl chr 2:233,602,732...233,621,129
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO protein:increased expression:microglia RGD PMID:11391707 RGD:5688244 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO DNA:polymorphisms, haplotype:cds:HLA-DQB1*0302 (human) RGD PMID:10511023 RGD:7365116 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO DNA:Haplotype: :HLA-DRB1*0407(human) RGD PMID:10511023 RGD:7365116 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G Serpine1 serpin family E member 1 ISO protein:increased expression:aqueous humor (human) RGD PMID:15710819 RGD:8547695 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link