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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3935
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ugt1a1
Name: UDP glucuronosyltransferase family 1 member A1
Acc ID: CHEBI:82285
Term: ortho-Aminoazotoluene
Definition: An azobenzene that has formula C14H15N3.
Chemical ID: MESH:D009762
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ugt1a1increases expressionISOUgt1a1 (Mus musculus)6480464CTDo-Aminoazotoluene results in increased expression of UGT1A1 mRNAPMID:21672546
Ugt1a1multiple interactionsISOUgt1a1 (Mus musculus)6480464CTDNR1I3 gene mutant form inhibits the reaction [o-Aminoazotoluene results in increased expression of UGT1A1 mRNA]PMID:21672546
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