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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tp53
Name: tumor protein p53
Acc ID: CHEBI:38940
Term: sunitinib
Definition: A pyrrole that has formula C22H27FN4O2.
Chemical ID: MESH:C473478
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tp53increases expression ISOTP53 (Homo sapiens)150537096RGDSunitinib increases expression of TP53 mRNA and protein in breast epithelium 
Tp53increases expressionEXP 6480464CTDSunitinib results in increased expression of TP53 proteinPMID:38101598
Tp53increases expressionISOTrp53 (Mus musculus)6480464CTDSunitinib results in increased expression of TP53 proteinPMID:38101598
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