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GENE - TERM ANNOTATION REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: DOID:8577
Term: ulcerative colitis
Definition: A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Ulcerative_colitis "DO" "DO", https://meshb.nlm.nih.gov/record/ui?ui=D003093 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnf IEP 10450593RGDprotein:increased expression:lung 
Tnf ISOTNF (Homo sapiens)14975153RGD  
TnftreatmentISOTnf (Mus musculus)10450577RGD  
Tnf ISOTNF (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:19617644 PMID:20452301 PMID:22119283
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