An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Chemical ID:
MESH:D010269
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Paraquat results in increased secretion of TNF protein]; [Mifepristone co-treated with Paraquat] results in increased expression of TNF protein; [Paraquat co-treated with Maneb] results in increased expression of TNF mRNA; [pirfenidone co-treated with Prednisolone] inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; allyl sulfide inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Ambroxol affects the reaction [Paraquat results in increased expression of TNF mRNA]; baicalin inhibits the reaction [Paraquat results in increased expression of TNF protein]; Dexamethasone inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Edaravone inhibits the reaction [Paraquat results in increased expression of TNF protein]; embelin inhibits the reaction [Paraquat results in increased expression of TNF protein]; fasudil inhibits the reaction [Paraquat results in increased expression of TNF protein]; ginkgolide C inhibits the reaction [Paraquat results in increased expression of TNF protein]; HDAC6 protein inhibits the reaction [Thalidomide inhibits the reaction [Paraquat results in increased expression of TNF protein]]; MIR141 promotes the reaction [Thalidomide inhibits the reaction [Paraquat results in increased expression of TNF protein]]; NFE2L2 protein inhibits the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of TNF protein]; Oxygen inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Paraquat promotes the reaction [Zinc results in increased expression of TNF protein]; Paraquat results in increased expression of and results in increased secretion of TNF protein; pirfenidone inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Prednisolone inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; pyrazolanthrone inhibits the reaction [Paraquat results in increased expression of and results in increased secretion of TNF protein]; pyrazolanthrone inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; Silymarin inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Thalidomide inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Thalidomide inhibits the reaction [Paraquat results in increased expression of TNF protein]; Thioctic Acid affects the reaction [Paraquat affects the expression of TNF protein]; Xuebijing inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Zinc promotes the reaction [Paraquat results in increased expression of TNF protein]
Paraquat results in increased expression of TNF; Paraquat results in increased expression of TNF mRNA; Paraquat results in increased expression of TNF protein
[BNIP3 protein co-treated with PINK1 protein] affects the reaction [Melatonin inhibits the reaction [Paraquat results in increased secretion of TNF protein]]; [Cyclophosphamide co-treated with Methylprednisolone] inhibits the reaction [Paraquat results in increased expression of TNF protein]; [Maneb co-treated with Paraquat] results in increased expression of TNF mRNA; [Paraquat co-treated with Maneb] results in increased expression of TNF mRNA; [Resveratrol co-treated with Tetracyclines] inhibits the reaction [Paraquat results in increased expression of TNF protein]; acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TNF mRNA]; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Paraquat results in increased expression of TNF protein]; Cyclophosphamide inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Dexamethasone inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; enterotoxin C, staphylococcal analog inhibits the reaction [Paraquat results in increased expression of TNF protein]; epigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; epigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of TNF protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Fingolimod Hydrochloride inhibits the reaction [Paraquat results in increased expression of TNF protein]; Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TNF mRNA]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; HSPD1 protein promotes the reaction [Paraquat results in increased expression of TNF mRNA]; IL17A protein promotes the reaction [Paraquat results in increased expression of TNF protein]; ITGAM protein affects the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TNF mRNA]; Melatonin inhibits the reaction [Paraquat results in increased secretion of TNF protein]; Minocycline inhibits the reaction [Paraquat results in increased expression of TNF protein]; MYD88 protein affects the reaction [Paraquat results in increased expression of TNF mRNA]; MYD88 protein affects the reaction [Paraquat results in increased expression of TNF protein]; naringin inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Oleanolic Acid inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Paraquat promotes the reaction [endotoxin, Escherichia coli results in increased expression of TNF protein]; Paraquat results in increased expression of and results in increased secretion of TNF protein; Phosphorothioate Oligonucleotides inhibits the reaction [Paraquat results in increased expression of and results in increased secretion of TNF protein]; Phosphorothioate Oligonucleotides inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; resolvin D1 analog inhibits the reaction [Paraquat results in increased expression of TNF protein]; SB 203580 inhibits the reaction [Paraquat promotes the reaction [endotoxin, Escherichia coli results in increased expression of TNF protein]]; SB 203580 inhibits the reaction [Paraquat results in increased expression of TNF protein]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TNF mRNA]; sodium boranocarbonate inhibits the reaction [Paraquat results in increased expression of TNF protein]; ST2825 inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; ST2825 inhibits the reaction [Paraquat results in increased expression of TNF protein]; T0901317 inhibits the reaction [Paraquat results in increased expression of TNF protein]; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; Thalidomide inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; TLR4 gene mutant form inhibits the reaction [Paraquat results in increased expression of TNF protein]; tricarbonylchloro(glycinato)ruthenium(II) inhibits the reaction [Paraquat results in increased expression of TNF protein]
[Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of TNF protein]; betadex analog promotes the reaction [ferulic acid inhibits the reaction [Paraquat results in increased expression of TNF protein]]; epigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of and results in increased secretion of TNF protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Paraquat results in increased expression of TNF protein]; fasudil inhibits the reaction [Paraquat results in increased secretion of TNF protein]; ferulic acid inhibits the reaction [Paraquat results in increased expression of TNF protein]; NFE2L2 protein inhibits the reaction [Paraquat results in increased expression of TNF protein]; Paraquat results in increased expression of and results in increased secretion of TNF protein; pyrazolanthrone inhibits the reaction [Paraquat results in increased expression of and results in increased secretion of TNF protein]; Resveratrol inhibits the reaction [Paraquat results in increased expression of TNF protein]; TLR9 protein promotes the reaction [Paraquat results in increased expression of and results in increased secretion of TNF protein]; TLR9 protein promotes the reaction [Paraquat results in increased expression of TNF mRNA]; TNF protein promotes the reaction [Paraquat results in increased expression of CAT protein]; TNF protein promotes the reaction [Paraquat results in increased expression of MT1A protein]; TNF protein promotes the reaction [Paraquat results in increased expression of SOD1 protein]; TNF protein promotes the reaction [Paraquat results in increased expression of SOD2 protein]; TNFAIP6 protein inhibits the reaction [Paraquat results in increased expression of TNF mRNA]