GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | increases expression | EXP | | 14995431 | RGD | Lindane increases expression of Tnf protein in serum | | Tnf | increases expression | EXP | | 6480464 | CTD | Hexachlorocyclohexane results in increased expression of TNF mRNA; Hexachlorocyclohexane results in increased expression of TNF protein | PMID:15025948 PMID:15135310 | Tnf | multiple interactions | EXP | | 6480464 | CTD | [Triiodothyronine co-treated with Hexachlorocyclohexane] results in increased expression of TNF mRNA; [Triiodothyronine co-treated with Hexachlorocyclohexane] results in increased expression of TNF protein; alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF mRNA]; alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF protein]; gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF mRNA]; gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF protein]; Hexachlorocyclohexane inhibits the reaction [Triiodothyronine results in increased expression of TNF protein] | PMID:15019085 PMID:15025948 | Tnf | decreases expression | ISO | TNF (Homo sapiens) | 6480464 | CTD | Hexachlorocyclohexane results in decreased expression of TNF protein | PMID:15319175 | Tnf | increases expression | ISO | Tnf (Mus musculus) | 6480464 | CTD | Hexachlorocyclohexane results in increased expression of TNF protein | PMID:28177269 | Tnf | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | [Lipopolysaccharides co-treated with Hexachlorocyclohexane] results in increased expression of TNF protein | PMID:28177269 | |
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