GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | decreases expression | EXP | | 6480464 | CTD | Gentamicins results in decreased expression of TNF protein | PMID:25051504 | Tnf | increases expression | EXP | | 6480464 | CTD | Gentamicins results in increased expression of TNF mRNA; Gentamicins results in increased expression of TNF protein | PMID:17132701 PMID:20623750 PMID:30368989 PMID:31628940 PMID:33387578 | Tnf | multiple interactions | EXP | | 6480464 | CTD | [candesartan co-treated with epigallocatechin gallate] inhibits the reaction [Gentamicins results in increased expression of TNF protein]; candesartan inhibits the reaction [Gentamicins results in increased expression of TNF protein]; Celecoxib inhibits the reaction [Gentamicins results in increased expression of TNF protein]; epigallocatechin gallate inhibits the reaction [Gentamicins results in increased expression of TNF protein]; Gentamicins inhibits the reaction [lipoxin A4 results in increased expression of TNF protein]; tetramethylpyrazine inhibits the reaction [TNF protein promotes the reaction [Gentamicins results in increased expression of CASP8 protein]]; TNF protein promotes the reaction [Gentamicins results in increased expression of CASP8 protein] | PMID:17132701 PMID:30368989 PMID:31628940 PMID:36057361 | Tnf | decreases expression | ISO | TNF (Homo sapiens) | 6480464 | CTD | Gentamicins results in decreased expression of TNF protein | PMID:17699551 | Tnf | increases expression | ISO | Tnf (Mus musculus) | 6480464 | CTD | Gentamicins results in increased expression of TNF mRNA | PMID:17442725 | Tnf | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of TNF mRNA]; Gentamicins inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Gentamicins promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Gentamicins promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein] | PMID:17442725 PMID:17699551 PMID:37269894 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | Gentamicins inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Gentamicins promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] | PMID:17699551 | | ||||||||||||||||||||||
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