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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3772
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Stat3
Name: signal transducer and activator of transcription 3
Acc ID: CHEBI:177802
Term: Cuprizon
Definition: null
Chemical ID: MESH:D003471
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Stat3increases expressionEXP 6480464CTDCuprizone results in increased expression of STAT3 mRNAPMID:26577399 PMID:27523638
Stat3increases expressionISOStat3 (Mus musculus)6480464CTDCuprizone results in increased expression of STAT3 protein modified formPMID:29864483
Stat3multiple interactionsISOStat3 (Mus musculus)6480464CTDLinagliptin inhibits the reaction [Cuprizone results in increased expression of STAT3 protein modified form]PMID:29864483
Stat3multiple interactionsISOSTAT3 (Homo sapiens)6480464CTD[Cuprizone co-treated with Benztropine] results in increased expression of STAT3 proteinPMID:34122009
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