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GENE - TERM ANNOTATION REPORT

RGD ID: 3729
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Snca
Name: synuclein alpha
Acc ID: GO:0007268
Term: chemical synaptic transmission
Definition: The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
Definition Source(s): GOC:jl, MeSH:D009435
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sncaacts_upstream_of_or_withinISOSnca (Mus musculus)1624291RGDMGI:1298397 MGI:1889011 PMID:20974939

PMID:20974939
Sncainvolved_inIBAMGI:1277151 or MGI:1298397 or MGI:1889011 or PANTHER:PTN000352385 or UniProtKB:P378401600115GO_CentralGO_REF:0000033

GO_REF:0000033
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