Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3645
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccl2
Name: C-C motif chemokine ligand 2
Acc ID: CHEBI:27915
Term: melamine
Definition: A trimer of cyanamide, with a 1,3,5-triazine skeleton.
Chemical ID: MESH:C011907
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl2increases expressionISOCCL2 (Homo sapiens)6480464CTDmelamine results in increased expression of CCL2 mRNAPMID:22915474
Ccl2multiple interactionsISOCCL2 (Homo sapiens)6480464CTD1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [melamine results in increased expression of CCL2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [melamine results in increased expression of CCL2 mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [melamine results in increased expression of CCL2 mRNA]; SB 203580 inhibits the reaction [melamine results in increased expression of CCL2 mRNA]; SN50 peptide inhibits the reaction [melamine results in increased expression of CCL2 mRNA]PMID:22915474
Go Back to source page   Continue to Ontology report