GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Raf1 | affects localization | ISO | Raf1 (Mus musculus) | 6480464 | CTD | Nicotine affects the localization of RAF1 protein | PMID:15574422 | Raf1 | increases activity | ISO | RAF1 (Homo sapiens) | 6480464 | CTD | Nicotine results in increased activity of RAF1 protein | PMID:17459420 | Raf1 | multiple interactions | ISO | RAF1 (Homo sapiens) | 6480464 | CTD | Aconitine analog inhibits the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]]; ARRB1 protein affects the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]]; Bungarotoxins inhibits the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]]; CHRNA7 protein affects the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]]; Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]; SRC protein affects the reaction [Nicotine promotes the reaction [RB1 protein binds to RAF1 protein]] | PMID:16862215 | |
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