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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3369
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ppara
Name: peroxisome proliferator activated receptor alpha
Acc ID: CHEBI:34709
Term: Diisodecyl phthalate
Definition: A phthalate ester that has formula C28H46O4.
Chemical ID: MESH:C042080
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pparaaffects bindingISOPPARA (Homo sapiens)6480464CTDdiisodecyl phthalate binds to PPARA proteinPMID:23843199
Pparaincreases activityISOPpara (Mus musculus)6480464CTDdiisodecyl phthalate results in increased activity of PPARA proteinPMID:30203046
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