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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3249
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Serpine1
Name: serpin family E member 1
Acc ID: CHEBI:46666
Term: crocidolite asbestos
Definition: null
Chemical ID: MESH:D017638
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Serpine1decreases expressionISOSerpine1 (Mus musculus)6480464CTDAsbestos, Crocidolite results in decreased expression of SERPINE1 mRNAPMID:23917077
Serpine1increases expressionISOSERPINE1 (Homo sapiens)6480464CTDAsbestos, Crocidolite results in increased expression of SERPINE1 mRNA; Asbestos, Crocidolite results in increased expression of SERPINE1 proteinPMID:17975199 PMID:18687144 PMID:29553831
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