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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3100
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp7
Name: matrix metallopeptidase 7
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp7decreases expressionISOMMP7 (Homo sapiens)6480464CTDLipopolysaccharides results in decreased expression of MMP7 mRNAPMID:21540303
Mmp7increases expressionISOMMP7 (Homo sapiens)6480464CTDLipopolysaccharides results in increased expression of MMP7 mRNAPMID:11739494 PMID:23724058 PMID:35953652
Mmp7multiple interactionsISOMMP7 (Homo sapiens)6480464CTDLipopolysaccharides promotes the reaction [Propofol results in increased expression of MMP7 mRNA]; phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of MMP7 mRNA]PMID:23724058 PMID:35953652
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