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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3100
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp7
Name: matrix metallopeptidase 7
Acc ID: CHEBI:9288
Term: streptozocin
Definition: An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Chemical ID: MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp7increases expressionISOMmp7 (Mus musculus)6480464CTDStreptozocin results in increased expression of MMP7 mRNAPMID:20446767
Mmp7multiple interactionsISOMmp7 (Mus musculus)6480464CTD[Streptozocin co-treated with Dietary Fats] results in increased expression of MMP7 mRNAPMID:29127188
Mmp7multiple interactionsISOMMP7 (Homo sapiens)6480464CTDPRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP7 mRNA]PMID:20446767
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