GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk3 | increases phosphorylation | EXP | | 6480464 | CTD | 4-hydroxy-2-nonenal results in increased phosphorylation of MAPK3 protein | PMID:24291486 | Mapk3 | decreases activity | ISO | Mapk3 (Mus musculus) | 6480464 | CTD | 4-hydroxy-2-nonenal results in decreased activity of MAPK3 protein | PMID:17263905 | Mapk3 | multiple interactions | ISO | MAPK3 (Homo sapiens) | 6480464 | CTD | 4-hydroxy-2-nonenal results in increased activity of and results in increased phosphorylation of MAPK3 protein | PMID:23845594 | Mapk3 | multiple interactions | ISO | Mapk3 (Mus musculus) | 6480464 | CTD | 4-hydroxy-2-nonenal results in decreased phosphorylation of and results in decreased activity of MAPK3 protein; 4-hydroxy-2-nonenal results in increased activity of [MAPK1 protein co-treated with MAPK3 protein]; 4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK3 protein; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in decreased phosphorylation of and results in decreased activity of MAPK3 protein] | PMID:16322078 PMID:24423726 | | ||||||||||||||||||||||
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