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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2939
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Jak2
Name: Janus kinase 2
Acc ID: CHEBI:31746
Term: kainic acid
Definition: A pyrrolidinecarboxylic acid that has formula C10H15NO4.
Chemical ID: MESH:D007608
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Jak2decreases expressionEXP 6480464CTDKainic Acid results in decreased expression of JAK2 proteinPMID:18711747
Jak2multiple interactionsISOJAK2 (Homo sapiens)6480464CTDEPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]]PMID:18711747
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