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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2934
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Itpr3
Name: inositol 1,4,5-trisphosphate receptor, type 3
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itpr3affects response to substanceISOItpr3 (Mus musculus)6480464CTDITPR3 protein affects the susceptibility to methylmercuric chloridePMID:33166615
Itpr3multiple interactionsISOItpr3 (Mus musculus)6480464CTDmethylmercuric chloride affects the reaction [ITPR3 protein affects the expression of CSF2 mRNA]; methylmercuric chloride affects the reaction [ITPR3 protein affects the expression of CSF2 protein]; methylmercuric chloride affects the reaction [ITPR3 protein affects the expression of IL27 mRNA]; methylmercuric chloride affects the reaction [ITPR3 protein affects the expression of IL6 mRNA]; methylmercuric chloride affects the reaction [ITPR3 protein affects the expression of IL6 protein]; methylmercuric chloride affects the reaction [ITPR3 protein affects the expression of NOTCH1 mRNA]; methylmercuric chloride affects the reaction [ITPR3 protein affects the expression of RELA mRNA]; methylmercuric chloride affects the reaction [ITPR3 protein affects the expression of RELA protein]PMID:33166615
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