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GENE - TERM ANNOTATION REPORT

RGD ID: 2903
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il6st
Name: interleukin 6 cytokine family signal transducer
Acc ID: GO:0070102
Term: interleukin-6-mediated signaling pathway
Definition: The series of molecular signals initiated by interleukin-6 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:add, GOC:BHF, GOC:mah, GOC:signaling
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il6st IMP 5686900RGD  
Il6stinvolved_inISOIL6ST (Homo sapiens)1624291RGD PMID:11884403 PMID:12643274 PMID:12829785 PMID:2261637 PMID:25731159

PMID:11884403 PMID:12643274 PMID:12829785 PMID:2261637 PMID:25731159
Il6stinvolved_inISOIl6st (Mus musculus)1624291RGD PMID:25731159

PMID:25731159
Il6stinvolved_inIEAUniProtKB:P40189 or ensembl:ENSP000003706981600115EnsemblGO_REF:0000107

GO_REF:0000107
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