GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il6 | multiple interactions | EXP | | 6480464 | CTD | chrysin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased expression of IL6 protein]; chrysin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; chrysin inhibits the reaction [Isoniazid results in increased expression of IL6 mRNA]; chrysin inhibits the reaction [Thioacetamide results in increased expression of IL6 protein] | PMID:23194824 PMID:30500344 PMID:33121995 PMID:37263553 | Il6 | decreases expression | ISO | IL6 (Homo sapiens) | 6480464 | CTD | chrysin results in decreased expression of IL6 mRNA | PMID:20816778 | Il6 | increases expression | ISO | IL6 (Homo sapiens) | 6480464 | CTD | chrysin results in increased expression of IL6 mRNA | PMID:18457675 | Il6 | multiple interactions | ISO | Il6 (Mus musculus) | 6480464 | CTD | chrysin inhibits the reaction [Oxidopamine results in increased expression of IL6 protein] | PMID:29054324 | Il6 | multiple interactions | ISO | IL6 (Homo sapiens) | 6480464 | CTD | chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA]; chrysin inhibits the reaction [nickel chloride results in increased expression of IL6 protein] | PMID:21515303 PMID:30016632 | |
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