GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | decreases expression | EXP | | 6480464 | CTD | Streptozocin results in decreased expression of IL1B protein | PMID:25541178 | Il1b | increases expression | EXP | | 6480464 | CTD | Streptozocin results in increased expression of IL1B mRNA; Streptozocin results in increased expression of IL1B protein | PMID:16129698 PMID:17167242 PMID:17589825 PMID:20643114 PMID:23647015 PMID:25635252 PMID:30817903 PMID:32202043 PMID:33639173 PMID:34477272 PMID:35305976 PMID:35442559 PMID:36504472 PMID:37224990 | Il1b | multiple interactions | EXP | | 6480464 | CTD | 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein]; [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of IL1B protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein; [Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of IL1B protein]; [Resveratrol co-treated with Streptozocin] results in increased expression of IL1B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein; [Streptozocin co-treated with Niacinamide co-treated with ENV-2 compound] results in decreased expression of IL1B mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of IL1B protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of IL1B protein]]; myrtenol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; palbinone inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; pinitol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL1B mRNA]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL1B protein]; Streptozocin results in increased expression of and results in increased secretion of IL1B protein; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of IL1B protein]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of IL1B protein] | PMID:12123627 PMID:16129698 PMID:17167242 PMID:17589825 PMID:20307516 PMID:20643114 PMID:21439372 PMID:23647015 PMID:24877639 PMID:25541178 PMID:25635252 PMID:25905778 PMID:26341651 PMID:28322830 PMID:30611788 PMID:30817903 PMID:31726037 PMID:32202043 PMID:33639173 PMID:34477272 PMID:35085591 PMID:35305976 PMID:35442559 PMID:36462176 PMID:36504472 PMID:36547818 PMID:37224990 | Il1b | increases expression | ISO | Il1b (Mus musculus) | 6480464 | CTD | Streptozocin results in increased expression of IL1B mRNA; Streptozocin results in increased expression of IL1B protein | PMID:18789669 PMID:20446767 PMID:27702591 PMID:28259689 PMID:30481507 PMID:30642005 PMID:30802477 PMID:34212273 PMID:34896238 PMID:34964214 | Il1b | multiple interactions | ISO | Il1b (Mus musculus) | 6480464 | CTD | [Chlorpyrifos co-treated with Streptozocin] results in increased expression of IL1B mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL1B protein; [Streptozocin co-treated with Dextran Sulfate] results in increased expression of IL1B protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of IL1B protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Alendronate inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B mRNA]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of IL1B protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Genistein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL1B protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] | PMID:18789669 PMID:27702591 PMID:28259689 PMID:30481507 PMID:30642005 PMID:30802477 PMID:33524429 PMID:34212273 PMID:34896238 PMID:34964214 PMID:35961541 PMID:37473909 PMID:37482253 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] | PMID:20446767 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |