GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | decreases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Eugenol results in decreased expression of IL1B mRNA | PMID:21939359 | Il1b | increases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Eugenol results in increased expression of IL1B mRNA | PMID:20713136 | Il1b | multiple interactions | ISO | Il1b (Mus musculus) | 6480464 | CTD | Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] | PMID:12963494 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | [Eugenol results in increased activity of sulforaphane] which results in decreased expression of IL1B; [sulforaphane results in increased activity of Eugenol] which results in decreased expression of IL1B; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]; Eugenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] | PMID:17509409 PMID:21382956 PMID:21807015 | | ||||||||||||||||||||||
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