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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2890
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1a
Name: interleukin 1 alpha
Acc ID: CHEBI:6918
Term: Mezerein
Definition: A diterpenoid that has formula C38H38O10.
Chemical ID: MESH:C011309
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1aincreases expressionISOIl1a (Mus musculus)6480464CTDmezerein results in increased expression of IL1A mRNA; mezerein results in increased expression of IL1A proteinPMID:7665919 PMID:8435107
Il1amultiple interactionsISOIl1a (Mus musculus)6480464CTDPlant Extracts inhibits the reaction [mezerein results in increased expression of IL1A mRNA]; Plant Extracts inhibits the reaction [mezerein results in increased expression of IL1A protein]PMID:7665919
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