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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il18
Name: interleukin 18
Acc ID: CHEBI:27906
Term: ubiquinone-0
Definition: A derivative of benzoquinone carrying a 5-methyl substituent; and methoxy substituents at positions 2 and 3. The core structure of the ubiquinone group of compounds.
Chemical ID: MESH:C109863
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il18decreases expressionISOIL18 (Homo sapiens)6480464CTDubiquinone-O results in decreased expression of IL18 proteinPMID:36847822
Il18multiple interactionsISOIL18 (Homo sapiens)6480464CTDubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]PMID:36847822
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