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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2886
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il10
Name: interleukin 10
Acc ID: CHEBI:64294
Term: 7-ketocholesterol
Definition: A cholestanoid that consists of cholesterol bearing an oxo substituent at position 7.
Chemical ID: MESH:C003001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il10decreases expressionISOIL10 (Homo sapiens)6480464CTD7-ketocholesterol results in decreased expression of IL10 mRNAPMID:24727230
Il10increases expressionISOIL10 (Homo sapiens)6480464CTD7-ketocholesterol results in increased expression of IL10 proteinPMID:24895526
Il10multiple interactionsISOIL10 (Homo sapiens)6480464CTDresveratrol promotes the reaction [7-ketocholesterol results in increased expression of IL10 protein]PMID:24895526
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