GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifnb1 | multiple interactions | ISO | IFNB1 (Homo sapiens) | 6480464 | CTD | ruxolitinib inhibits the reaction [IFNB1 protein results in increased expression of CXCL10 mRNA]; ruxolitinib inhibits the reaction [IFNB1 protein results in increased expression of CXCL11 mRNA]; ruxolitinib inhibits the reaction [IFNB1 protein results in increased expression of IRF1 mRNA]; ruxolitinib inhibits the reaction [IFNB1 protein results in increased expression of IRF9 mRNA]; ruxolitinib inhibits the reaction [IFNB1 protein results in increased expression of SP100 mRNA]; ruxolitinib inhibits the reaction [IFNB1 protein results in increased expression of STAT1 mRNA]; ruxolitinib inhibits the reaction [IFNB1 protein results in increased expression of STAT2 mRNA]; ruxolitinib inhibits the reaction [IFNB1 protein results in increased expression of TLR3 mRNA] | PMID:28365849 | |
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